Last update 06 Dec 2025

BI-473494

Overview

Basic Info

Drug Type
Synthetic peptide
Synonyms
BI 473494
Target
AMYR
Action
agonists
Mechanism
AMYR agonists(Amylin receptor agonists)
Therapeutic Areas
Endocrinology and Metabolic Disease
Active Indication-
Inactive Indication
Diabetes MellitusObesity
Originator Organization
Zealand Pharma A/SZealand Pharma A/S
Active Organization-
Inactive Organization
C.H. Boehringer Sohn AG & Co. KGBoehringer Ingelheim GmbHBoehringer Ingelheim GmbHZealand Pharma A/SZealand Pharma A/S
License Organization-
Drug Highest PhaseDiscontinuedPhase 1
First Approval Date-
Regulation-
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Related

1
Clinical Trials associated with BI-473494
NCT03195088
/ TerminatedPhase 1
Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single Rising Subcutaneous Doses of BI 473494 in Healthy Male Subjects (Single-blind, Partially Randomised, Placebo-controlled Parallel Group Design)
100 Clinical Results associated with BI-473494
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100 Translational Medicine associated with BI-473494
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100 Patents (Medical) associated with BI-473494
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100 Deals associated with BI-473494
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Diabetes MellitusPhase 1-
C.H. Boehringer Sohn AG & Co. KG
-
Diabetes MellitusPhase 1-
Zealand Pharma A/SZealand Pharma A/S
-
ObesityPhase 1
Germany
Boehringer Ingelheim GmbHBoehringer Ingelheim GmbH
-
ObesityPhase 1-
C.H. Boehringer Sohn AG & Co. KG
-
ObesityPhase 1-
Zealand Pharma A/SZealand Pharma A/S
-
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
NCT03195088 (CTgov)
Phase 1
-
16
(BI 473494 35 μg)
eppjzrtqhu = zovenctkuf uykgdtjudm (saxrtlgwfq, qtdcscapls - cotnyukryt)
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-
22 Jun 2022
(BI 473494 75 μg)
eppjzrtqhu = iirckktjqm uykgdtjudm (saxrtlgwfq, uvcrqldnfn - xjszaifzuh)
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Translational Medicine

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Deal

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Core Patent

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Clinical Trial

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Approval

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Biosimilar

Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.
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Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

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