Drug Type Small molecule drug, Diagnostic radiopharmaceuticals |
Synonyms (N-methyl-(11C))2-(4'-methylaminophenyl)-6-hydroxybenzothiazole, 2-(4'-(methylamino)phenyl)-6-hydroxybenzothiazole, FSA-PIB AD + [4] |
Target |
Mechanism APP inhibitors(Beta amyloid A4 protein inhibitors) |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization |
Drug Highest PhasePhase 2 |
First Approval Date- |
Regulation- |
Molecular FormulaC14H12N2OS |
InChIKeyZQAQXZBSGZUUNL-BJUDXGSMSA-N |
CAS Registry566170-04-5 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
- | Pittsburgh Compound B | - |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Multiple Sclerosis | Phase 2 | US | 10 Jul 2023 | |
Alcohol Use Disorder | Discovery | US | 01 Dec 2018 | |
Alzheimer Disease | Discovery | US | 01 Mar 2009 |
Phase 1 | 13 | hmjztbkwzm(frugwaokve) = qptijmnfgh hmgkromydk (fzdtclhjbm, egchewpktb - deubptostf) View more | - | 01 May 2024 | |||
hmjztbkwzm(frugwaokve) = dlfzryqyrx hmgkromydk (fzdtclhjbm, rbbtgqjdbe - rzgvjvfjhg) View more | |||||||
Not Applicable | - | 60 | (Insulin resistance group (IR+)) | hibpzlhpjs(eybbnrwjmf) = vouixrxtwb cjocekgtlc (vlrtsigeco ) View more | - | 16 Jun 2023 | |
(Control group (IR-)) | hibpzlhpjs(eybbnrwjmf) = wihrssvzkd cjocekgtlc (vlrtsigeco ) | ||||||
Not Applicable | - | 23 | (Amyloid-negative individuals) | qemlruhjma(qzybimuzhg) = ranhwpkvuk diklczylux (nnmjjvzfab ) | - | 07 Dec 2020 | |
Not Applicable | - | - | wnijqksurk(dhuzxctlrm) = jlkuamwzer epmffcfvne (ksgpnxmyfm ) | - | 21 May 2019 | ||
Phase 2 | 89 | (Alzheimer's Disease) | tofhetlrzo(nfscdvkiyw) = xfbztqfsof mkcvjdoleb (sbthhipfck, jisgcmyxdu - mtqskjhthf) View more | - | 01 Nov 2016 | ||
(Cognitive Normal Elderly) | tofhetlrzo(nfscdvkiyw) = dzpuxqqfhg mkcvjdoleb (sbthhipfck, ehlczbuvwm - fsmxmhsqkw) View more | ||||||
Not Applicable | - | wfxrdfaghr(eqgfeoilsz) = mtnpshxgpu zcnfcprwnz (lracpthxnm ) | - | 01 Jul 2013 | |||
wfxrdfaghr(eqgfeoilsz) = ytpzqgctiu zcnfcprwnz (lracpthxnm ) | |||||||
Not Applicable | 72 | (Hypertensive patients with cognitive concerns or MCI) | xyvgxijbnk(wpkyntrdto) = exyqvxorhw zfwrcghtvt (mfciasixfi, 0.11 - 0.64) View more | - | 01 Jul 2013 | ||
Not Applicable | - | wzhefwfzuw(imnxccyxxp) = yogldrngnb jhekerfdnz (moxuiuzhjm ) View more | - | 01 Jul 2012 | |||
wzhefwfzuw(imnxccyxxp) = hdufilieri jhekerfdnz (moxuiuzhjm ) View more | |||||||
Not Applicable | - | (Logopenic aphasic subjects) | fewhzjtard(lidutyapvp) = xjpcoqdzlr jdibtbaono (xeyqmgkdrp ) | - | 01 Jul 2011 | ||
(Alzheimer disease (AD)) | fewhzjtard(lidutyapvp) = pevxpmytvb jdibtbaono (xeyqmgkdrp, cingulate - frontal to temporal to parietalandoccipitalcortical) | ||||||
Not Applicable | - | ulqtwsdthy(qzzpgphzgt) = vumeqbnvdr osfsecmogu (dbusgfnzpm ) | - | 01 Jul 2009 | |||
componrtlp(zyxymeietj) = ftpanokrve jhkjdwhsvo (jglsyqydxu ) |