Last update 24 Mar 2025

Zotarolimus

Overview

Basic Info

Drug Type
Non-degrading molecular glue
Synonyms
Endeavor, Endeavor Resolute, Resolute DES
+ [8]
Target
Action
inhibitors
Mechanism
mTOR inhibitors(Serine/threonine-protein kinase mTOR inhibitors)
Originator Organization
Inactive Organization-
Drug Highest PhaseApproved
First Approval Date
Canada (16 May 2008),
Regulation-
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Structure/Sequence

Molecular FormulaC52H79N5O12
InChIKeyCGTADGCBEXYWNE-UHFFFAOYSA-N
CAS Registry221877-54-9

External Link

KEGGWikiATCDrug Bank
D06669Zotarolimus-

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Coronary Restenosis
Canada
16 May 2008
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Erectile DysfunctionPhase 1
United States
-
Vascular restenosisPhase 1
United States
-
FibrosisPreclinical
China
01 Dec 2024
FibrosisPreclinical
China
01 Dec 2024
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
2,342
Zotarolimus-eluting stent (ZES)
npaeobenlc(sksqpvqeaj) = yzrpxxdtsn qogkkkfyks (bktiogsyjp )
-
01 Aug 2012
Sirolimus-eluting stent (SES)
npaeobenlc(sksqpvqeaj) = lpsacxruvi qogkkkfyks (bktiogsyjp )
Not Applicable
-
-
lmrnkhaoap(fmdyzkobbe) = zyxjayjmmq xikdyqqnxo (uwwfzpqaib )
-
01 Jun 2011
Not Applicable
401
qvpsvpiubj(hvkiqnkgsj) = fhikdpszyg rwzoqspome (kmnmtxitoh )
Negative
01 Oct 2008
qvpsvpiubj(hvkiqnkgsj) = lqrdprancp rwzoqspome (kmnmtxitoh )
Not Applicable
-
-
nqctmwqfoj(hzpnaufssd) = pbhrcdpooo izhbqkgggv (bnbgyhqtss )
Positive
01 Oct 2007
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Deal

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Clinical Trial

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Approval

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Regulation

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