Last update 21 Nov 2024

Amitriptyline/Ketamine

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
AmiKet
Mechanism
Monoamine reuptake inhibitor, NMDA receptor agonists(Glutamate [NMDA] receptor agonists)
Therapeutic Areas
Originator Organization
Inactive Organization
Drug Highest PhasePhase 3
First Approval Date-
RegulationOrphan Drug (US)
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Structure

Molecular FormulaC13H16ClNO
InChIKeyYQEZLKZALYSWHR-UHFFFAOYSA-N
CAS Registry6740-88-1
View All Structures (2)

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Neurotoxicity SyndromesPhase 3--
Neurotoxicity SyndromesPhase 3--
PainPhase 3--
PainPhase 3--
Peripheral Nervous System DiseasesPhase 3--
Peripheral Nervous System DiseasesPhase 3--
Neuralgia, PostherpeticPhase 2
IN
01 Jul 2007
Behavioural disordersDiscovery
IN
01 Jul 2007
Diabetic peripheral neuropathyDiscovery
IN
01 Jul 2007
NeuropathyDiscovery
IN
01 Jul 2007
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
360
(Amitriptyline 4% Ketamine 2% Cream, Placebo Capsules)
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-
06 Jul 2011
(Gabapentin Capsules, Placebo Cream)
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Phase 2
226
placebo cream
(Placebo Cream)
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-
17 May 2011
okhbicfaju(khnhvdxbom) = bdgclgfxhn nikqsglnsa (nxssivhmvq, kzunrwobrf - lfqhpvmrde)
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Approval

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Regulation

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