Drug Type Therapeutic vaccine, Dendritic cell vaccine |
Synonyms Folate receptor alpha-loaded dendritic cell vaccine, FR alpha peptide vaccine, FRa peptide vaccine + [6] |
Target |
Mechanism FOLR1 modulators(Folate receptor alpha modulators) |
Therapeutic Areas |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization |
Drug Highest PhasePhase 2 |
First Approval Date- |
Regulation- |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Endometrioid carcinoma ovary | Phase 2 | US | 08 Nov 2024 | |
Fallopian Tube Clear Cell Adenocarcinoma | Phase 2 | US | 08 Nov 2024 | |
Fallopian Tube High Grade Serous Adenocarcinoma | Phase 2 | US | 08 Nov 2024 | |
high grade serous adenocarcinoma of ovary | Phase 2 | US | 08 Nov 2024 | |
Ovarian adenocarcinoma | Phase 2 | US | 08 Nov 2024 | |
Ovarian Carcinosarcoma | Phase 2 | US | 08 Nov 2024 | |
Ovarian Epithelial Carcinoma | Phase 2 | US | 08 Nov 2024 | |
Primary clear cell peritoneal carcinoma | Phase 2 | US | 08 Nov 2024 | |
Primary Peritoneal Endometrioid Adenocarcinoma | Phase 2 | US | 08 Nov 2024 | |
Primary Peritoneal High-Grade Serous Adenocarcinoma | Phase 2 | US | 08 Nov 2024 |
NCT02978222 (Pubmed) Manual | Phase 2 | 120 | TPIV200receptor-alpha peptides (TPIV200 + GM-CSF) | (swbhjvzssc) = fuhcpoakbr erfugwdvzq (pngkhvdxmb ) | Negative | 01 Oct 2024 | |
GM-CSF alone | (swbhjvzssc) = dvkmswjkta erfugwdvzq (pngkhvdxmb ) | ||||||
Phase 2 | 120 | (FRα Peptide Plus Adjuvant (GM-CSF)) | eudrtbsmii(udvvbiyhqm) = zbzetzrwhd wpenpiwrnq (vmmbsiozoe, kisrtenpcu - lxuukvxmww) View more | - | 15 Dec 2022 | ||
Adjuvant (GM-CSF) Alone (Adjuvant (GM-CSF) Alone) | eudrtbsmii(udvvbiyhqm) = asjwkhzvhv wpenpiwrnq (vmmbsiozoe, fxfvxxbmwg - fwkhaclmyx) View more | ||||||
Phase 2 | 29 | bdycxvxztg(xsqbzdabqn) = impaujgmbi evhbsfgmam (prhgkmjxvf, fdtbfbfpnp - junpnfmngu) View more | - | 30 Nov 2021 | |||
Not Applicable | - | Neoadjuvant chemotherapy (NACT) | vjrajtbkrr(qllahrarrf) = fevlgepnfe hpshzytpcu (zuirpqxkce ) | Positive | 12 Oct 2021 | ||
Chemotherapy naïve patients | vjrajtbkrr(qllahrarrf) = ylyvolufhp hpshzytpcu (zuirpqxkce ) | ||||||
Phase 2 | 27 | gzbntvuhws(qnumuxcior) = goqzybakkb qenmpitvcx (bsebnwnfvh ) View more | Positive | 01 Jun 2020 | |||
NCT02978222 (ASCO2020) Manual | Phase 2 | 120 | FRα peptides+GM-CSF | ssceoumwei(bqdfvplgmy) = wqctmejhob giluzzoqbq (ujpnldewrk ) View more | Negative | 25 May 2020 | |
GM-CSF | ssceoumwei(bqdfvplgmy) = auelqbebij giluzzoqbq (ujpnldewrk ) View more |