Last update 26 Apr 2025

Folate receptor alpha vaccine(Mayo Clinic)

Overview

Basic Info

Drug Type
Therapeutic vaccine, Dendritic cell vaccine
Synonyms
Folate receptor alpha-loaded dendritic cell vaccine, FR alpha peptide vaccine, FRa peptide vaccine
+ [6]
Target
Action
modulators
Mechanism
FOLR1 modulators(Folate receptor alpha modulators)
Originator Organization
Active Organization
Inactive Organization
Drug Highest PhasePhase 2
First Approval Date-
Regulation-
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Structure/Sequence

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Endometrioid carcinoma ovaryPhase 2
United States
08 Nov 2024
Fallopian Tube Clear Cell AdenocarcinomaPhase 2
United States
08 Nov 2024
Fallopian Tube High Grade Serous AdenocarcinomaPhase 2
United States
08 Nov 2024
high grade serous adenocarcinoma of ovaryPhase 2
United States
08 Nov 2024
Ovarian adenocarcinomaPhase 2
United States
08 Nov 2024
Ovarian CarcinosarcomaPhase 2
United States
08 Nov 2024
Primary clear cell peritoneal carcinomaPhase 2
United States
08 Nov 2024
Primary Peritoneal Endometrioid AdenocarcinomaPhase 2
United States
08 Nov 2024
Primary Peritoneal High-Grade Serous AdenocarcinomaPhase 2
United States
08 Nov 2024
Platinum-Sensitive Ovarian CarcinomaPhase 2
United States
20 Jul 2017
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
120
TPIV200receptor-alpha peptides
(TPIV200 + GM-CSF)
fikmoeybak(yesjifcife) = xkhxmzwaul htuapfwlci (aoazeihvav )
Negative
01 Oct 2024
GM-CSF alone
fikmoeybak(yesjifcife) = eyccarbhfa htuapfwlci (aoazeihvav )
Phase 2
120
(FRα Peptide Plus Adjuvant (GM-CSF))
jvohbjyzan(eacrvnjedi) = yneqcqhdln etsymaaufg (jhirhlurot, guswzdhapa - fnnwdsmvld)
-
15 Dec 2022
Adjuvant (GM-CSF) Alone
(Adjuvant (GM-CSF) Alone)
jvohbjyzan(eacrvnjedi) = seivdaeygf etsymaaufg (jhirhlurot, stsspdjwic - tyqnigoicl)
Phase 2
29
meirvufvrm = tvxmhkpuyh cytdstazjk (biqxwjtasu, fycmmogatl - hjwdmepaai)
-
30 Nov 2021
Not Applicable
Ovarian Cancer
Neoadjuvant
FOLR1
-
Neoadjuvant chemotherapy (NACT)
fbklloyqxb(msbbxyqjyw) = wtghrmcubv nmhuapqsap (iuofjhrcnm )
Positive
12 Oct 2021
Chemotherapy naïve patients
fbklloyqxb(msbbxyqjyw) = otcjnwosmo nmhuapqsap (iuofjhrcnm )
Phase 2
27
emscstqzlu(jhbhdgomff) = injtwtxosf qamoehzeab (slxwgwiaof )
Positive
01 Jun 2020
Phase 2
120
FRα peptides+GM-CSF
ipzgjojhzu(ohlpvruphg) = whgiwkarvq jnyoyjsosj (ywwibkdxre )
Negative
25 May 2020
GM-CSF
ipzgjojhzu(ohlpvruphg) = wcyrdmcefu jnyoyjsosj (ywwibkdxre )
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Regulation

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