Last update 01 Nov 2024

Folate receptor alpha vaccine(Mayo Clinic)

Overview

Basic Info

Drug Type
Therapeutic vaccine, Dendritic cell vaccine
Synonyms
Folate receptor alpha-loaded dendritic cell vaccine, FR alpha peptide vaccine, FRa peptide vaccine
+ [6]
Target
Mechanism
FOLR1 modulators(Folate receptor alpha modulators)
Originator Organization
Active Organization
Inactive Organization
Drug Highest PhasePhase 2
First Approval Date-
Regulation-
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Endometrioid carcinoma ovaryPhase 2
US
12 Nov 2024
Fallopian Tube Clear Cell AdenocarcinomaPhase 2
US
12 Nov 2024
Fallopian Tube High Grade Serous AdenocarcinomaPhase 2
US
12 Nov 2024
high grade serous adenocarcinoma of ovaryPhase 2
US
12 Nov 2024
Ovarian adenocarcinomaPhase 2
US
12 Nov 2024
Ovarian CarcinosarcomaPhase 2
US
12 Nov 2024
Ovarian Epithelial CarcinomaPhase 2
US
12 Nov 2024
Primary clear cell peritoneal carcinomaPhase 2
US
12 Nov 2024
Primary Peritoneal Endometrioid AdenocarcinomaPhase 2
US
12 Nov 2024
Primary Peritoneal High-Grade Serous AdenocarcinomaPhase 2
US
12 Nov 2024
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Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
120
TPIV200
gnotowdwzk(pnfuvcxbqv) = pjlxdjkyrk dtlxglninl (xoethmrrky )
Negative
01 Oct 2024
GM-CSF alone
gnotowdwzk(pnfuvcxbqv) = mxotlzvogt dtlxglninl (xoethmrrky )
Phase 2
120
(FRα Peptide Plus Adjuvant (GM-CSF))
qnriwkzztf(lkxezfwmcs) = tsvtzcvfxo wzyshtmbnl (sbfrmakuev, ypzfklnpnh - fxrxixsjrl)
-
15 Dec 2022
Adjuvant (GM-CSF) Alone
(Adjuvant (GM-CSF) Alone)
qnriwkzztf(lkxezfwmcs) = uzxsrlqicu wzyshtmbnl (sbfrmakuev, dyytwzuujv - wwrqbdmvow)
Phase 2
29
fjwyntuyhl(czxbreqhaw) = rdyfmwmzej dbftvrmbri (uwjkyfjzqh, xqmtulufov - fbmeeqcpak)
-
30 Nov 2021
Not Applicable
Ovarian Cancer
Neoadjuvant
FOLR1
-
Neoadjuvant chemotherapy (NACT)
nhoylbrgrz(giwvesjyvv) = xsgnawrhnr wcrdvzflae (chkreceuuw )
Positive
12 Oct 2021
Chemotherapy naïve patients
nhoylbrgrz(giwvesjyvv) = ftedwcpltf wcrdvzflae (chkreceuuw )
Phase 2
27
yqtfenctdb(kjxlcrwueg) = xqhwdbzsru uouafvnaza (zytpujikbl )
Positive
01 Jun 2020
Phase 2
120
FRα peptides+GM-CSF
emddetcbzw(etyggcgdch) = liatrglxjo bwaamuglzn (gijwodyteq )
Negative
25 May 2020
GM-CSF
emddetcbzw(etyggcgdch) = mjdnyrdtjb bwaamuglzn (gijwodyteq )
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Regulation

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