Last update 02 Nov 2024

Halofuginone Hydrobromide

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
(+/-)-trans-7-bromo-6-chloro-3-(3-(3-hydroxy-2-piperidyl)-acetonyl)-4(3H)-quinazolinone, Halofuginone, Halofuginone hydrobromide (USAN)
+ [6]
Target
Mechanism
Collagen inhibitors, Angiogenesis inhibitors
Active Indication-
Originator Organization
Active Organization-
Drug Highest PhaseDiscontinuedPhase 2
First Approval Date-
RegulationOrphan Drug (US)
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Structure

Molecular FormulaC16H18Br2ClN3O3
InChIKeySJUWEPZBTXEUMU-AJYMSAGVSA-N
CAS Registry64924-67-0

External Link

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Muscular Dystrophy, DuchennePhase 2
US
01 Oct 2013
Bladder CancerPhase 2
IL
-
Bladder CancerPhase 2
GB
-
NeoplasmsPhase 2
BE
--
NeoplasmsPhase 2--
NeoplasmsPhase 2
NL
--
Scleroderma, SystemicPhase 2
GB
-
Coronary RestenosisPreclinical
US
--
Liver CirrhosisPreclinical
IL
-
Renal fibrosisPreclinical
IL
-
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
-
-
kuiwzcrghe(wjaxprwfhf) = bhhyyhejka lnuxisrylr (zroyqahidv )
-
01 May 2022
PBS
kuiwzcrghe(wjaxprwfhf) = vwxhavydkv lnuxisrylr (zroyqahidv )
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Clinical Trial

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Approval

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Regulation

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