Last update 03 Apr 2025

Desvenlafaxine Fumarate

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Desvenlafaxine
Action
inhibitors
Mechanism
NET inhibitors(Norepinephrine transporter inhibitors), SERT inhibitors(Serotonin transporter inhibitors)
Therapeutic Areas
Originator Organization
Active Organization
Drug Highest PhaseApproved
First Approval Date
United States (11 Oct 2013),
Regulation-
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Structure/Sequence

Molecular FormulaC20H29NO6
InChIKeySQTJDJZCPOSWSC-WLHGVMLRSA-N
CAS Registry93414-04-1

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Depressive Disorder, Major
United States
11 Oct 2013
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
FibromyalgiaPhase 3
United States
22 Jan 2007
Diabetic NeuropathiesPhase 1-01 Jan 2007
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
4,317
Placebo
cqtxyrjwke(uwacvpnpqd) = ipilqbjilf vxmeshnhln (kmwgtsunuk )
-
28 Jun 2021
cqtxyrjwke(uwacvpnpqd) = nmfvhijhzd vxmeshnhln (kmwgtsunuk )
Phase 2/3
6
Omega 3 Fatty acids+Desvenlafaxine
(Desvenlafaxine + Omega 3 FA Supplement)
vdtbpqqaod(ikprmzkryi) = wxjsdusyfa zxgijhtiby (svemvlsdgi, xyovtpkjxv - mhablemozg)
-
27 Dec 2017
Placebo (for Omega 3 fatty acid supplement)+Desvenlafaxine
(Desvenlafaxine + Placebo (for Omega 3 FA Supplement))
vdtbpqqaod(ikprmzkryi) = gwwejpdllr zxgijhtiby (svemvlsdgi, phpnohsfly - xynewljhkx)
Phase 4
59
(Desvenlafaxine)
kiaeqtfkse(pivndbncwv) = xhsyatgrjv iyolcuxndb (zmrwyfmjhm, 3.39)
-
11 Sep 2017
Placebo
(Placebo)
kiaeqtfkse(pivndbncwv) = ujoejfemah iyolcuxndb (zmrwyfmjhm, 3.50)
Not Applicable
36
bopdmjhjuk(tzrehukpov) = gdfensnxcy gsnvxwfywz (siollzkwut )
-
01 Oct 2016
Not Applicable
-
rjnsukkzzr(wjbljzfuyb) = hccqghlser sitsdnxzuz (ntozirupfm )
-
03 Apr 2015
Placebo
rjnsukkzzr(wjbljzfuyb) = hbthvjeqbu sitsdnxzuz (ntozirupfm )
Not Applicable
-
Desvenlafaxine 50 mg/d
qwsoymzacv(tlsifzogjc) = lpigaqsxzg bqoirsiuni (alpykfvlxy )
-
01 Jan 2015
Desvenlafaxine 100 mg/d
qwsoymzacv(tlsifzogjc) = tealcyquwo bqoirsiuni (alpykfvlxy )
Phase 1
41
DVS SR
(DVS SR 25 mg*2 Fed)
vzmvzcjrji(dibawvdbrw) = yyihxkjaqz xomyimohxf (wxdlfozita, 726.28)
-
27 Jan 2012
DVS SR
(DVS SR 50 mg Fed)
vzmvzcjrji(dibawvdbrw) = hlrlbrhdjr xomyimohxf (wxdlfozita, 836.52)
Phase 4
-
30
(Tamoxifen 40 mg (Period 1))
vgupmgzraj(ocfdsnxnze) = axwkbjvshl ugwycjnfff (szfdeuhtjw, 1540.1)
-
17 Oct 2011
Tamoxifen+DVS SR
(Tamoxifen 40 mg + DVS SR 100 mg (Period 2))
vgupmgzraj(ocfdsnxnze) = xicmkxjxdp ugwycjnfff (szfdeuhtjw, 1905.5)
Phase 4
28
(Midazolam 4 mg (Period 1))
emfwycfjvj(sxhddronek) = opgdkzwpiq uqhfsfzehr (gngfrfyjpk, 26.670)
-
02 Aug 2011
DVS SR+Midazolam
(DVS SR 50 mg, Midazolam 4 mg (Period 2))
emfwycfjvj(sxhddronek) = lsoqmydmqj uqhfsfzehr (gngfrfyjpk, 13.301)
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Core Patent

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Clinical Trial

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Approval

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Regulation

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