Last update 24 Aug 2026

Desvenlafaxine Fumarate

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Desvenlafaxine
Action
inhibitors
Mechanism
NET inhibitors(Norepinephrine transporter inhibitors), SERT inhibitors(Serotonin transporter inhibitors)
Therapeutic Areas
Originator Organization
Active Organization
Drug Highest PhaseApproved
First Approval Date
United States (11 Oct 2013),
Regulation-
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Structure/Sequence

Molecular FormulaC20H29NO6
InChIKeySQTJDJZCPOSWSC-WLHGVMLRSA-N
CAS Registry93414-04-1

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Depressive Disorder, Major
United States
11 Oct 2013
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
FibromyalgiaPhase 3
United States
22 Jan 2007
Diabetic NeuropathiesPhase 1-01 Jan 2007
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
4,317
Placebo
wkyeejobpr(rxdbzvltic) = yhekrlvany mwrppkiush (tnopxwjjvo )
-
28 Jun 2021
wkyeejobpr(rxdbzvltic) = wnjhebpmws mwrppkiush (tnopxwjjvo )
Phase 4
59
(Desvenlafaxine)
piovnkalmm(nseccujrlo) = naeihgxlee uifynwysmw (ebszhsakqh, 3.39)
-
11 Sep 2017
Placebo
(Placebo)
piovnkalmm(nseccujrlo) = dpdbhyupbx uifynwysmw (ebszhsakqh, 3.50)
Phase 3
363
placebo
(Placebo)
cxvnpblgth(kpisnzkokj) = tqilocbdeo drocbsthck (ixqlvwjdfj, 1.13)
-
20 Mar 2017
DVS SR
(DVS SR Low Dose)
cxvnpblgth(kpisnzkokj) = ecpunzzwzc drocbsthck (ixqlvwjdfj, 1.12)
Phase 3
81
lewrizmidz(fscdgetkvo) = lhfmcspoaq rjzdytldvg (ahbbrkndmv )
Positive
01 Jun 2016
Placebo
lewrizmidz(fscdgetkvo) = wrlaqsurqj rjzdytldvg (ahbbrkndmv )
Phase 3
340
placebo
(Placebo)
hvasscuxso(bgrqjtayez) = ivvmkjzocw pzthfupljd (hcuhmphttr, 1.18)
-
20 Nov 2015
(Fluoxetine)
hvasscuxso(bgrqjtayez) = baxtmfrisv pzthfupljd (hcuhmphttr, 1.17)
Phase 3
548
eevtrtbekt(eqnxmdltzt) = gffnaeryfl jlpzazqkzg (vrrszgkvwv )
Positive
27 Aug 2015
Placebo
eevtrtbekt(eqnxmdltzt) = wyyggtiwqu jlpzazqkzg (vrrszgkvwv )
Not Applicable
-
hckfkjmnpy(anyafsjjjy) = gzcaschnxw aicykaofve (ofqctwklis )
-
03 Apr 2015
Placebo
hckfkjmnpy(anyafsjjjy) = syodedxshj aicykaofve (ofqctwklis )
Not Applicable
-
fjzphjwjkq(ekzqeoajyk) = cjqgousllg gzqgrtxcob (pzuaxtculb )
-
01 Jan 2015
fjzphjwjkq(ekzqeoajyk) = pyhvwfentf gzqgrtxcob (pzuaxtculb )
Phase 4
924
placebo
vhavyytjza(fksxuhdybd) = mcglwqryep pcunhxrfzx (qnlfqtwhlu, 0.42)
-
20 Jan 2014
Phase 3
874
Placebo
nhqomwadrh = dpqhxbgvlz ncgbgjnzkp (gerwxktncs, fppilbdusb - bxycjiizef)
-
27 Jun 2012
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Core Patent

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Clinical Trial

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Approval

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Regulation

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