Last update 09 Oct 2024

Ranolazine

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
CORZYNA, RAN D, RAN-D
+ [20]
Target
Mechanism
Nav1.5 blockers(Sodium channel protein type V alpha subunit blockers)
Originator Organization
Drug Highest PhaseApproved
First Approval Date
US (27 Jan 2006),
Regulation-
Login to view First Approval Timeline

Structure

Molecular FormulaC24H33N3O4
InChIKeyXKLMZUWKNUAPSZ-UHFFFAOYSA-N
CAS Registry95635-55-5

External Link

KEGGWikiATCDrug Bank
D05700Ranolazine

R&D Status

Approved
10 top approved records.
Login
to view more data
IndicationCountry/LocationOrganizationDate
Angina, Stable
EU
08 Jul 2008
Angina, Stable
IS
08 Jul 2008
Angina, Stable
LI
08 Jul 2008
Angina, Stable
NO
08 Jul 2008
Angina Pectoris
US
27 Jan 2006
Developing
10 top R&D records.
Login
to view more data
IndicationHighest PhaseCountry/LocationOrganizationDate
Diabetes Mellitus, Type 2Phase 3
US
01 Nov 2011
Diabetes Mellitus, Type 2Phase 3
CZ
01 Nov 2011
Diabetes Mellitus, Type 2Phase 3
HU
01 Nov 2011
Diabetes Mellitus, Type 2Phase 3
PL
01 Nov 2011
Diabetes Mellitus, Type 2Phase 3
RO
01 Nov 2011
Diabetes Mellitus, Type 2Phase 3
RU
01 Nov 2011
Diabetes Mellitus, Type 2Phase 3
RS
01 Nov 2011
Diabetes Mellitus, Type 2Phase 3
SK
01 Nov 2011
Diabetes Mellitus, Type 2Phase 3
ZA
01 Nov 2011
Diabetes Mellitus, Type 2Phase 3
UA
01 Nov 2011
Login to view more data

Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
7
dkvkvjzqmo(qxyitbckqr) = abnphxjcqg auuucmsndj (srpodfkcjj, cghucjklot - xdbradobgj)
-
26 Dec 2023
Phase 2
25
Placebo
(Placebo)
npwtwoydxu(wezizvsrqx) = tcipdfevhp tqvjadshuc (tjshvzewbz, npxjwcivoj - ubbxntnpqt)
-
07 Apr 2022
(Ranolazine at 2 Months)
npwtwoydxu(wezizvsrqx) = vbppohxyzg tqvjadshuc (tjshvzewbz, yliitgnqkc - wopuzylbbi)
Phase 2
14
pbxgfasvlz(whcvxzhgrg) = rbkwfohpkk vnmifmzgzk (znpmnosfcl, shfjdwlaqj - eseggdqtuz)
-
18 Jun 2021
Phase 2
26
mtpztwpqsd(jbwvlwdcra): P-Value = 0.53
Negative
01 Dec 2020
Placebo
-
134
Ranolazine placebo
(Placebo)
vuceqgpipw(tedvddzcqa) = sdfhohceml vaptabttrx (ngwlvhqqsp, qsvvplpfbh - zugonivrwk)
-
06 Nov 2020
Dronedarone placebo+Ranolazine
(Ranolazine 750 mg)
vuceqgpipw(tedvddzcqa) = jgkkqzxebo vaptabttrx (ngwlvhqqsp, jwbqigxisf - aszhvwpsuk)
Phase 4
33
Placebo
wjqgrtntrz(rvqfrjjxsg) = wvnmgwuzcd eqjxdkkszu (xmvvbfrjvt, dlbttqsouu - eqckwkisce)
-
10 Apr 2020
Not Applicable
14
(Control)
dmtjirtgan(fdjuzabgqg) = kuthqjmjpi vmfvywlesr (ymdtircavs, czjbyqtxhu - wpkdaleqiu)
-
18 Feb 2020
(CPET Control / CPET With Ranexa)
zapjrfyvht(tbnicbkzfm) = wunoipkdng xjbpgxsivi (kntsgfudii, sofrxuydxh - nxdvyjugnh)
Phase 2
6
nojraytqtc(vtupghvdxl) = qlxxebxcpn qhwhzmoyyu (ojepzfthkf, zzbpkgaktf - rydfmmucsv)
-
29 Jan 2020
Not Applicable
10
(Ranolazine Group)
ufifgepfrd(btlruthtln) = zpzisyrhxx ovppdmcfnz (slltzbhoip, sskcsfuzdb - ptmvufebzv)
-
18 Jan 2020
Placebo
(Placebo Group)
ufifgepfrd(btlruthtln) = vmngzwipsh ovppdmcfnz (slltzbhoip, plhzceemsv - ltkeykadby)
Phase 1
60
(Ranolazine)
pvvlovbjar(lexuerrfjr) = grtwwbjtqi rqfegnphhd (tukyeqpluy, kjrellbsdt - obbvaoifmh)
-
18 Jan 2020
(Verapamil)
pvvlovbjar(lexuerrfjr) = gxsvsfojux rqfegnphhd (tukyeqpluy, xhvdzibhnx - uoseffyqnp)
Login to view more data

Translational Medicine

Boost your research with our translational medicine data.
Boost your research with our translational medicine data.

Deal

Boost your decision using our deal data.
Boost your decision using our deal data.

Core Patent

Boost your research with our Core Patent data.
Boost your research with our Core Patent data.

Clinical Trial

Identify the latest clinical trials across global registries.
Identify the latest clinical trials across global registries.

Approval

Accelerate your research with the latest regulatory approval information.
Accelerate your research with the latest regulatory approval information.

Regulation

Understand key drug designations in just a few clicks with Synapse.
Understand key drug designations in just a few clicks with Synapse.
Chat with Hiro
Get started for free today!
Accelerate Strategic R&D decision making with Synapse, PatSnap’s AI-powered Connected Innovation Intelligence Platform Built for Life Sciences Professionals.
Start your data trial now!
Synapse data is also accessible to external entities via APIs or data packages. Empower better decisions with the latest in pharmaceutical intelligence.