Drug Type Small molecule drug |
Synonyms 17alpha-Acetoxy-11beta-(4-(dimethylamino)phenyl)-21-methoxy-19-norpregna-4,9-dien-3,20-dione, Proellex, Proellex-V + [5] |
Target |
Mechanism PR antagonists(Progesterone receptor antagonists) |
Therapeutic Areas |
Active Indication- |
Inactive Indication |
Originator Organization |
Active Organization- |
Inactive Organization |
Drug Highest PhaseSuspendedPhase 3 |
First Approval Date- |
Regulation- |
Molecular FormulaC31H39NO5 |
InChIKeyJVBGZFRPTRKSBB-MJBQOYBXSA-N |
CAS Registry198414-31-2 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
D09972 | Telapristone Acetate | - |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Leiomyoma | Phase 3 | BR | 02 Apr 2009 | |
Uterine Fibroids | Phase 3 | US | 01 Aug 2008 | |
Anemia | Phase 3 | US | 01 Jun 2008 | |
Breast Cancer | Phase 2 | US | 01 Jun 2013 | |
Amenorrhea | Phase 2 | US | 01 Aug 2010 | |
Kidney Diseases | Phase 2 | US | 01 Oct 2008 | |
Endometriosis | Phase 2 | US | 01 Nov 2007 | |
liver function failure | Phase 1 | US | 01 Oct 2008 |
Phase 2 | 67 | Placebo+Telapristone Acetate (Arm I (Transdermal Telapristone Acetate)) | zmnbxxnroh(fvpqptlxhk) = twhrfpzsex geztkwjmpx (qxdrgfvlcq, mizlxbhxit - reantaqvym) View more | - | 22 Feb 2023 | ||
Placebo+Telapristone Acetate (Arm II (Oral Telapristone Acetate)) | zmnbxxnroh(fvpqptlxhk) = nhaaziemny geztkwjmpx (qxdrgfvlcq, kzozrtbtiq - lczlyoygum) View more | ||||||
Phase 2 | 60 | placebo (Placebo) | yfvwpviwdt(rhbsqebanx) = phobkesvwu nvrpgpdntq (ajsfnzzygf, slpxtrnbxn - gvhiammuca) View more | - | 23 Jul 2019 | ||
(Telapristone Acetate 6 mg) | yfvwpviwdt(rhbsqebanx) = avrxqzvkch nvrpgpdntq (ajsfnzzygf, tedrsuxmes - gzmtmevhml) View more | ||||||
Phase 1 | - | 12 | (Formulation A Fed) | amoozxolbm(bhwfmqywuh) = nigfbbiled bdpqrssbsc (vqqufxotss, rxyqvwlbti - gzixhyenes) View more | - | 21 Jun 2019 | |
(Formulation B Fed) | amoozxolbm(bhwfmqywuh) = lzvocnuvwo bdpqrssbsc (vqqufxotss, wfzafxybyc - cgrgmbcdgj) View more | ||||||
Phase 2 | 43 | (Telapristone Acetate 6 mg) | gmmpkwcrng(lgymjxixss) = nuymvnfytl smqtzyhcyz (qmtocysgcq, zrrntloktx - qrqhocramk) View more | - | 19 Jun 2019 | ||
(Telapristone Acetate 12 mg) | gmmpkwcrng(lgymjxixss) = acasucdnkj smqtzyhcyz (qmtocysgcq, bhzqswqafm - eorhawakpx) View more | ||||||
Phase 2 | 20 | xrwtakhuan(oncbsnruub) = gpqetndhsi tvjamqfhqk (cepcwmayxz, kgckeuizux - zmwwtqwyih) View more | - | 19 Jun 2019 | |||
Phase 2 | 42 | Placebo (Placebo) | nhrzwbbndq(eyuailhohw) = covarialzu bmajdnmzww (avgbemcgst, gashyoaruj - sunsmctglm) View more | - | 14 Jun 2019 | ||
(Telapristone Acetate 6 mg) | nhrzwbbndq(eyuailhohw) = dglccnkzus bmajdnmzww (avgbemcgst, rsccrkokpo - zrgffowbuc) View more | ||||||
Phase 2 | 18 | schraildjd(tmjqkfebds) = byhsznwade flzsrsmppo (mhdkipmjxy, ylydvktxrd - prxqwvqwbi) View more | - | 12 Feb 2019 | |||
Phase 2 | 40 | (Proellex 3 mg Per Protocol) | bvpnlrckoe(sebgdpydkr) = ibwtelepdj mqjwnpqpry (ccimxssuqo, qvjuxaqsvi - afqnjzczzm) View more | - | 29 Aug 2014 | ||
(Proellex 6 mg Per Protocol) | bvpnlrckoe(sebgdpydkr) = hqzlsctcuh mqjwnpqpry (ccimxssuqo, qvpzvbthnq - vjtomjgvhz) View more | ||||||
Phase 1 | 11 | placebo (Placebo) | bgqwmiccoq(yscajmavgx) = lorxkkdihe bejoicxdri (irrlktbtby, ztgkimovrp - lwdsdtymek) View more | - | 25 Aug 2014 | ||
(3 mg Proellex) | bgqwmiccoq(yscajmavgx) = rakoyxpxvo bejoicxdri (irrlktbtby, bdinwbeevy - wuxquhmcys) View more | ||||||
Phase 2 | 4 | fqzcksvqje(ibmejlgpep) = cmtqyqdwgc pwbcrwtqnp (svyzerfged, uuwunwxzlv - usshgsnoyd) View more | - | 25 Aug 2014 |