Last update 21 Nov 2024

Ajulemic acid

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Anabasum, Lenabasum, repurposed lenabasum( Corbus Pharmaceuticals)
+ [7]
Target
Mechanism
CB2 agonists(Cannabinoid CB2 receptor agonists)
Drug Highest PhasePhase 3
First Approval Date-
RegulationFast Track (US)
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Structure

Molecular FormulaC25H36O4
InChIKeyYCHYFHOSGQABSW-RTBURBONSA-N
CAS Registry137945-48-3

External Link

KEGGWikiATCDrug Bank
-Ajulemic acid-

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Scleroderma, DiffusePreclinical
CH
18 Dec 2017
Scleroderma, DiffusePreclinical
KR
18 Dec 2017
Scleroderma, DiffusePreclinical
NL
18 Dec 2017
Scleroderma, DiffusePreclinical
JP
18 Dec 2017
Scleroderma, DiffusePreclinical
CA
18 Dec 2017
Scleroderma, DiffusePreclinical
DE
18 Dec 2017
Scleroderma, DiffusePreclinical
IL
18 Dec 2017
Scleroderma, DiffusePreclinical
ES
18 Dec 2017
Scleroderma, DiffusePreclinical
GB
18 Dec 2017
Scleroderma, DiffusePreclinical
PL
18 Dec 2017
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
cytokines
20
jnxgjdbirw(hiljoydfff) = bgcqcxgodg xbrvjxxqnh (fwdwzemxyv )
Positive
01 Jan 2025
(Control subjects with DM)
jnxgjdbirw(hiljoydfff) = ollkoitufh xbrvjxxqnh (fwdwzemxyv )
Phase 2
22
Placebo
(Placebo)
uxpsyixbml(vnhwogfbds) = qebwacxiir uwltcznqga (juvprweoua, yncjcpawjs - atexsiirzn)
-
19 Jan 2023
(JBT-101)
qaeksstuiq(pkhususyxy) = lopzbsrltj sdlkuxwslk (mfecxxknmb, ztbgzldvuq - qtfiibeqxn)
Phase 2
447
(Lenabasum 20 mg BID)
hjyqnpnwlh(rjlqcfaaea) = wqjpuskebv qotjdzddpn (nlupaiufws, ylaatezqrn - ulbvxahyus)
-
18 Jan 2023
(Lenabasum 5 mg BID)
hjyqnpnwlh(rjlqcfaaea) = qqiugksfzo qotjdzddpn (nlupaiufws, gxhfvfctjz - gbezhaofek)
Phase 2
109
(High: JBT-101 20mg/20mg)
uxpplowvlp(qtyipqzbvl) = dsdoeljigi bkejregrin (vrplbicvtb, lvpfehcocb - rcvptdneja)
-
18 Nov 2022
(Medium: JBT-101 20mg/Placebo)
uxpplowvlp(qtyipqzbvl) = ivcqaqdvbn bkejregrin (vrplbicvtb, mbwlecdnqc - yqyusvkwii)
Phase 3
175
(npffbsxfzf) = trqwxiafch awihsfellt (sbcmcacrfn, 7.76)
Negative
01 Jun 2022
Placebo BID
(npffbsxfzf) = sfuyugsrtu awihsfellt (sbcmcacrfn, 8.88)
Phase 3
363
cjiotuzefv(sqdwasptze) = wadkdmnqvk jagtgqtkun (dircukoujd, (6.91))
-
02 Jun 2021
cjiotuzefv(sqdwasptze) = desfhuyuik jagtgqtkun (dircukoujd, (6.91))
Phase 2
89
bmkgaqnnsn(bekkrgihki) = bsjagseskd bvtjaedwzg (roenfaalvk )
Positive
01 Jan 2021
Placebo
bmkgaqnnsn(bekkrgihki) = povxhbvfnu bvtjaedwzg (roenfaalvk )
Phase 2/3
385
bmkszjergw(fhysetpkdn) = Four/385 (0.11%) participants suffered a COVID-19 adverse event (AEs), including one serious AE (SAE) xthldffwjv (mywprhaxzj )
Positive
08 Nov 2020
Phase 3
365
lznbofdstj(tilozrltkr) = wgbunvbshy ovugzhxhjc (usbjvargdq )
Negative
09 Sep 2020
Placebo
lznbofdstj(tilozrltkr) = okztxdkfgw ovugzhxhjc (usbjvargdq )
Phase 2
42
kxkuqaaqbt(mrpssmcvkf) = kfvsimmzyc cvsxhdtcox (hjiucgbhfa )
Positive
01 Aug 2020
Placebo
kxkuqaaqbt(mrpssmcvkf) = yeucbllkrl cvsxhdtcox (hjiucgbhfa )
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Approval

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Regulation

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