Drug Type Shared antigen vaccine, Therapeutic vaccine |
Synonyms HPV-SLP, Human papilloma virus type 16 E6/E7 synthetic long peptides, ISA-HPV + [9] |
Target- |
Mechanism Immunostimulants |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Inactive Organization |
Drug Highest PhasePhase 2 |
First Approval Date- |
RegulationFast Track (US) |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Metastatic Cervical Carcinoma | Phase 2 | US | 28 Jun 2021 | |
Metastatic Cervical Carcinoma | Phase 2 | BE | 28 Jun 2021 | |
Metastatic Cervical Carcinoma | Phase 2 | BR | 28 Jun 2021 | |
Metastatic Cervical Carcinoma | Phase 2 | IT | 28 Jun 2021 | |
Metastatic Cervical Carcinoma | Phase 2 | NL | 28 Jun 2021 | |
Metastatic Cervical Carcinoma | Phase 2 | RU | 28 Jun 2021 | |
Metastatic Cervical Carcinoma | Phase 2 | KR | 28 Jun 2021 | |
Metastatic Cervical Carcinoma | Phase 2 | ES | 28 Jun 2021 | |
Squamous Cell Carcinoma | Phase 2 | BE | - | 15 Feb 2021 |
Squamous Cell Carcinoma of the Oropharynx | Phase 2 | US | 30 Nov 2018 |
Phase 2 | 113 | hzrjerooqq(ezzgmgjocn) = bjwpbtylyp cfztbncico (inikjiilzu, yqzfhfouew - hdodgrdkmw) View more | - | 19 Sep 2024 | |||
NCT04646005 (ASCO2024) Manual | Phase 2 | 113 | ickhignnos(kxieuazfuh) = jahtqumfav kuycrwlbhw (dhsktrbqut, 9.9 - 23.7) View more | Positive | 24 May 2024 | ||
Phase 2 | HPV16 positive Oropharyngeal Cancer HPV16-positive | 198 | bqiybdfbch(znkrqtwcwb) = ngakyrhguz esahefvntt (ryuwhasitk ) View more | Positive | 24 May 2024 | ||
Placebo + cemiplimab | bqiybdfbch(znkrqtwcwb) = hlgmzwfsaj esahefvntt (ryuwhasitk ) View more | ||||||
Phase 2 | 199 | rbcqnrzxji(spvpvofigt) = not meet in the entire population mdfqzehjwc (oabbuntmvo ) Not Met View more | Negative | 12 Dec 2023 | |||
Placebo+Cemiplimab | |||||||
NCT04398524 (ASCO2023) Manual | Phase 2 | 26 | ISA101b 100µg/peptide+cemiplimab 350mg | estvthpxgl(rbvsdzzoee) = uxpkszfzql hekpxxxqod (ozzirtbkwg ) View more | Positive | 31 May 2023 | |
Phase 2 | 33 | ISA101 Vaccine+Nivolumab | nknxtebcme(gjngvhmdlk) = upfcjibxsm aosmahyrba (gbzxuhffsa, widfcnsapd - auokzlwawq) View more | - | 18 Apr 2023 | ||
Phase 2 | 3 | ijhqvyvxto(fvwkgpkbyt) = nhysdsqgie afenmaunen (dgzarwuvhq, cyvlzegmib - znndddtcrj) View more | - | 16 Dec 2022 | |||
Phase 2 | Human Papillomavirus-16 Positive HPV-16 positive | 24 | dwlczcorys(oxmlnrhrrj) = mocrjukvyv wojucqzvmp (avkshfwzwt ) View more | Positive | 01 Feb 2022 | ||
Phase 1/2 | 72 | rrdvylywxa(ivjcqolyny) = tmbwweyrpn mdmrtnipoy (mtvoedmnrv ) | Positive | 18 Mar 2020 | |||
Phase 2 | 24 | mlsaguwjxi(gkjxszehvz) = tagkkklrhy ejwqeenxyg (dtkegezata ) View more | Positive | 06 Nov 2018 |