Last update 15 Feb 2025

MK-6913

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
MK 6913
Target
ERβ
Mechanism
ERβ agonists(Estrogen receptor beta agonists)
Therapeutic Areas
Cardiovascular DiseasesOther Diseases
Active Indication-
Inactive Indication
Hot FlashesVascular DiseasesVasomotor symptom
Originator Organization
Karo Bio USA, Inc.Karo Bio USA, Inc.
Active Organization-
Inactive Organization
Karo Bio USA, Inc.Karo Bio USA, Inc.Merck Sharp & Dohme LLCMerck GmbH
Drug Highest PhaseDiscontinuedPhase 2
First Approval Date-
Regulation-
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Related

1
Clinical Trials associated with MK-6913
NCT01015677
/ TerminatedPhase 2
A Phase IIa, Randomized, Double-Blind, Placebo- and Active-Controlled Study to Examine MK-6913 for the Treatment of Vasomotor Symptoms in Postmenopausal Women
100 Clinical Results associated with MK-6913
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100 Translational Medicine associated with MK-6913
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100 Patents (Medical) associated with MK-6913
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100 Deals associated with MK-6913
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Hot FlashesPhase 2-
Merck Sharp & Dohme LLC
17 Dec 2009
Vasomotor symptomPhase 2-
Merck Sharp & Dohme LLC
17 Dec 2009
Vascular DiseasesPhase 2-
Karo Bio USA, Inc.Karo Bio USA, Inc.
-
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
NCT01015677 (6913-004, CTgov)
Phase 2
Vasomotor symptom | Hot Flashes
99
Placebo to 17-β estradiol+MK-6913
(MK-6913 75 mg)
axryndzluu(vytizludca) = zfjnhrosmf xcqszipndy (chtyernbdv, xvlqeexhhv - dyudvgytvb)
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-
04 May 2016
Placebo to MK-6913+17-β estradiol
(17-β Estradiol 1 mg)
axryndzluu(vytizludca) = nlhpjdscnz xcqszipndy (chtyernbdv, piwbimhitn - wmqwbxpiuh)
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Approval

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Regulation

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