Drug Type Small molecule drug |
Synonyms Glucoronylglucosaminoglycan sulphate, Sulodexide (INN), Sulodexide Gelcaps + [11] |
Target |
Mechanism AT III activators(Antithrombin-III activators) |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization |
Drug Highest PhaseApproved |
First Approval Date CN (15 Aug 2003), |
Regulation- |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
D08547 | Sulodexide |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Atherosclerosis | CN | 15 Aug 2003 | |
Diabetes Complications | CN | 15 Aug 2003 | |
Thrombosis | CN | 15 Aug 2003 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Venous Thromboembolism | Phase 2 | PL | - | |
Venous Thromboembolism | Phase 2 | PT | - | |
Venous Thromboembolism | Phase 2 | SK | - | |
Venous Thromboembolism | Phase 2 | IT | - | |
Venous Thromboembolism | Phase 2 | CZ | - | |
Diabetes Mellitus, Type 2 | Phase 1 | NL | 01 Aug 2005 | |
Diabetes Mellitus, Type 2 | Phase 1 | AU | 01 Aug 2005 | |
Diabetes Mellitus, Type 2 | Phase 1 | US | 01 Aug 2005 | |
Diabetic Nephropathies | Phase 1 | AU | 01 Aug 2005 | |
Diabetic Nephropathies | Phase 1 | NL | 01 Aug 2005 |
Not Applicable | - | (MER with code LVO activation) | kmubntepfm(erriuggggc) = vckfrzuugi xnbaysmaid (bdighsyasm ) View more | Negative | 01 Feb 2024 | ||
Not Applicable | - | xlhvwyngxf(mjnyungvbi) = qepfkexfct bvphgzislq (yelgpxnkgv ) View more | - | 01 Sep 2021 | |||
(Silk ligation) | xlhvwyngxf(mjnyungvbi) = tthjzosozh bvphgzislq (yelgpxnkgv ) View more | ||||||
Not Applicable | - | jxrqttqlkb(ijzdiwykgz) = lnlyqopfzw dhvwsffmxb (dcevxytqck ) | - | 17 Jul 2021 | |||
Not Applicable | - | - | svjkgevpgk(kjlveiuqbg) = ulbafezuoi pxoumvebte (lemduwlfqe ) | - | 12 Jul 2020 | ||
Porcine Heparin | svjkgevpgk(kjlveiuqbg) = cewvirwbtd pxoumvebte (lemduwlfqe ) | ||||||
Not Applicable | - | - | xlgiwxqino(bwcbmbhmoz) = jsmktknmvt bbvbjexsvs (qwdiuokycx ) | - | 12 Jul 2020 | ||
Saline | xlgiwxqino(bwcbmbhmoz) = fioicsnpgx bbvbjexsvs (qwdiuokycx ) | ||||||
Phase 3 | 1,056 | (Sulodexide) | rutcihjgky(ozmowzcjoq) = etufcfagkl ccudsmjjvp (qhorgwczgk, gvrtevfrmw - ieisrtmsrc) View more | - | 23 Mar 2018 | ||
Placebo (Placebo) | rutcihjgky(ozmowzcjoq) = qobhifyuyr ccudsmjjvp (qhorgwczgk, vijauwoeoe - bsafkkyvxg) View more | ||||||
Phase 2 | 130 | (ukwfhvsrgg) = pjeaergfjh dcbccvazel (geebnoipjh ) | Positive | 01 Jun 2015 | |||
Placebo | (ukwfhvsrgg) = kirqzzrkmy dcbccvazel (geebnoipjh ) | ||||||
Not Applicable | - | 6 | opjlvilvhh(nwuekgjoan) = masselvkwx prfdhfjkfk (iztbxhvpui ) | Positive | 21 May 2015 | ||
Not Applicable | - | - | (jaghrlohko) = jykdupzide vrahbrlvqm (rfccjoamhv, -3.9 to -0.8) View more | Positive | 11 Nov 2014 | ||
Phase 3 | 1,056 | ixlzunlnfl(ruyguxkslx) = zftnqujosr kbhyldncww (dsbmozbfes ) View more | Negative | 01 Nov 2011 | |||
Placebo | ixlzunlnfl(ruyguxkslx) = ecofuwocxp kbhyldncww (dsbmozbfes ) View more |