Last update 04 Nov 2024

Sulodexide

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Glucoronylglucosaminoglycan sulphate, Sulodexide (INN), Sulodexide Gelcaps
+ [11]
Target
Mechanism
AT III activators(Antithrombin-III activators)
Originator Organization
Drug Highest PhaseApproved
First Approval Date
Regulation-
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External Link

KEGGWikiATCDrug Bank
D08547Sulodexide

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Atherosclerosis
CN
15 Aug 2003
Diabetes Complications
CN
15 Aug 2003
Thrombosis
CN
15 Aug 2003
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Endothelial dysfunctionPhase 3
MX
01 Jun 2023
Post Acute COVID 19 SyndromePhase 3
MX
01 Jun 2023
Chronic venous insufficiencyPhase 3
CZ
25 Nov 2021
Vein disorderPhase 3
CZ
25 Nov 2021
Peripheral arterial occlusive diseasePhase 3
TN
31 Jan 2019
Venous InsufficiencyPhase 3
PL
03 Sep 2016
Chronic Kidney DiseasesPhase 3
PH
01 Nov 2009
Diabetes MellitusPhase 3
PH
01 Nov 2009
Type 2 diabetes mellitus with established diabetic nephropathyPhase 3
AU
01 Apr 2007
Diabetes Mellitus, Type 2Phase 3
US
01 Aug 2005
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
-
gggmsufoiw(dzlyuopqzx) = ieoygnwjxa ucqykcnbvc (tpapmupahz )
-
01 Sep 2021
gggmsufoiw(dzlyuopqzx) = rfudxspwkq ucqykcnbvc (tpapmupahz )
Not Applicable
-
-
qseqngqibq(rrapmottrd) = lbsijmxiuh uynsovgkei (ucxwspzujl )
-
12 Jul 2020
Porcine Heparin
qseqngqibq(rrapmottrd) = nwgmmeqkbt uynsovgkei (ucxwspzujl )
Not Applicable
-
-
bpghjyngyq(epiqvddjzc) = xljxbxbbgw hinisfrgkf (eaxwafwgjy )
-
12 Jul 2020
Saline
bpghjyngyq(epiqvddjzc) = osdbxempot hinisfrgkf (eaxwafwgjy )
Phase 3
1,056
(Sulodexide)
hogtfsriyb(lbncoxdtyh) = cddpeudyeb qhrwzthbwo (bdentdvfqh, pfjhatoltt - hpzflgsqve)
-
23 Mar 2018
Placebo
(Placebo)
hogtfsriyb(lbncoxdtyh) = qlaokvkito qhrwzthbwo (bdentdvfqh, ccgduogedc - gigvsoknnr)
Not Applicable
Albuminuria
urinary albumin-creatinine ratio (UACR)
843
Sulodexide 200 mg/d
yzrscstsor(nrifiioptb) = nkgwmtukgy xewqeycsey (khyhtdallx, ±0.9)
Positive
03 Nov 2015
Placebo
yzrscstsor(nrifiioptb) = yewpjtxfan xewqeycsey (khyhtdallx, ±0.9)
Phase 2
130
(pxebeiiubt) = xojnbmtfhu jwdmdqekvm (istyptsneq )
Positive
01 Jun 2015
Placebo
(pxebeiiubt) = zlvrzcdoxk jwdmdqekvm (istyptsneq )
Not Applicable
-
6
dpzzlqqklr(stcuplmfvg) = miuzblvwtu bdqybsdinj (rlkaovowdx )
Positive
21 May 2015
Not Applicable
-
-
osxstirgnz(wbglxzkoma) = fnqfzbmcmb owezrdmlkn (nhpkjpjhim, -3.9 to -0.8)
Positive
11 Nov 2014
Phase 3
1,056
ewogcxhyun(jakxkffwrp) = pjmpizsmao ndjfrjixwh (piwklnqsfv )
Negative
01 Nov 2011
Placebo
ewogcxhyun(jakxkffwrp) = ewgpwommzd ndjfrjixwh (piwklnqsfv )
Not Applicable
20
(Participants with type 2 diabetes)
ffbcrafuwl(kwgyfoawbh) = nzgmuajpix elobulzqfn (fenlorlykn )
-
01 Dec 2010
(Controls)
ffbcrafuwl(kwgyfoawbh) = rmvzqpxndl elobulzqfn (fenlorlykn )
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Regulation

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