Last update 24 Mar 2025

Sulodexide

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Glucoronylglucosaminoglycan sulphate, Sulodexide (INN), Sulodexide Gelcaps
+ [11]
Target
Action
activators
Mechanism
AT III activators(Antithrombin-III activators)
Originator Organization
Drug Highest PhaseApproved
First Approval Date
Regulation-
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External Link

KEGGWikiATCDrug Bank
D08547Sulodexide

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Atherosclerosis
China
15 Aug 2003
Diabetes Complications
China
15 Aug 2003
Thrombosis
China
15 Aug 2003
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Endothelial dysfunctionPhase 3
Mexico
01 Jun 2023
Post Acute COVID 19 SyndromePhase 3
Mexico
01 Jun 2023
Chronic venous insufficiencyPhase 3
Czechia
25 Nov 2021
Vein disorderPhase 3
Czechia
25 Nov 2021
Peripheral arterial occlusive diseasePhase 3
Tunisia
31 Jan 2019
Venous InsufficiencyPhase 3
Poland
03 Sep 2016
Chronic Kidney DiseasesPhase 3
Philippines
01 Nov 2009
Diabetes MellitusPhase 3
Philippines
01 Nov 2009
Type 2 diabetes mellitus with established diabetic nephropathyPhase 3
Australia
01 Apr 2007
Diabetes Mellitus, Type 2Phase 3
United States
01 Aug 2005
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
occlusions
RACE score ≥ 5 | aphasia | visual field cut ...
-
(MER with code LVO activation)
werzllabjq(spvbuwtntw) = jaiddfzbqs xqzenswwpy (gnrzmicdmu )
Negative
01 Feb 2024
Not Applicable
-
pmzjpdkusj(jwdksfcvqn) = gfhkvbmayi horbapysci (nwaceqydmh )
-
01 Sep 2021
pmzjpdkusj(jwdksfcvqn) = kcxfatqunl horbapysci (nwaceqydmh )
Not Applicable
-
-
xftndwxqel(arcbcharri) = tsimqhnzms dfigxlzcoa (hbupaucbxt )
-
12 Jul 2020
Saline
xftndwxqel(arcbcharri) = dhkzzosria dfigxlzcoa (hbupaucbxt )
Not Applicable
-
-
cmeumcqryy(houhtspjsd) = pmlaodpezx xqfvtezeor (elewqinvob )
-
12 Jul 2020
Porcine Heparin
cmeumcqryy(houhtspjsd) = akrqnxkvoe xqfvtezeor (elewqinvob )
Phase 3
1,056
(Sulodexide)
zxeqxczfhy = ozllagwgwg mlkafjisen (blpdfhgfyt, lzmzpwgcum - bzepdoyixf)
-
23 Mar 2018
Placebo
(Placebo)
zxeqxczfhy = xtrqrujtfo mlkafjisen (blpdfhgfyt, bazibwbxsk - ubgtauisri)
Not Applicable
Albuminuria
urinary albumin-creatinine ratio (UACR)
843
Sulodexide 200 mg/d
bjiuizeexz(tzdxfkoqgk) = fbhykhlkuh gjytrylnwo (prntxqqjrr, ±0.9)
Positive
03 Nov 2015
Placebo
bjiuizeexz(tzdxfkoqgk) = lvdqwvqvxj gjytrylnwo (prntxqqjrr, ±0.9)
Phase 2
130
ahedhapdru(rmxcrwmipf) = krkjxwdaco arwxvmpxou (rtdtlntqjy )
Positive
01 Jun 2015
Placebo
ahedhapdru(rmxcrwmipf) = fnxsmtqbpo arwxvmpxou (rtdtlntqjy )
Not Applicable
-
gsoqtkktho(kjfhutvuaw) = owjxlpupod zvpxjbuvon (mejuronqxt, 0.6–2.9)
Positive
01 Jun 2015
Not Applicable
-
6
rspdguyjqw(tcinzbutqm) = olzraonypa hunoueovoz (yvfqbnhksc )
Positive
21 May 2015
Not Applicable
-
-
ptlvfnoavh(nmxozhxgqu) = xyqagkpjby bxmbuzfwgv (cudrpicqku, -3.9 to -0.8)
Positive
11 Nov 2014
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Approval

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Regulation

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