Last update 20 Mar 2025

BO-112

Overview

Basic Info

Drug Type
Oligonucleotide
Synonyms
Action
stimulants, agonists
Mechanism
MDA5 stimulants(interferon induced with helicase C domain 1 stimulants), RIG-I stimulants(Retinoic acid-inducible gene I stimulants), TLR3 agonists(Toll like receptor 3 agonists)
Originator Organization
Inactive Organization
Drug Highest PhasePhase 2
First Approval Date-
Regulation-
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Structure/Sequence

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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Stomach CancerPhase 2
Spain
-
Colorectal CancerPreclinical
Spain
17 Jun 2020
Colorectal CancerPreclinical
Italy
17 Jun 2020
Colorectal CancerPreclinical
Belgium
17 Jun 2020
Esophageal CarcinomaPreclinical
Spain
17 Jun 2020
Esophageal CarcinomaPreclinical
Belgium
17 Jun 2020
Esophageal CarcinomaPreclinical
Italy
17 Jun 2020
Gastrooesophageal junction cancerPreclinical
Belgium
17 Jun 2020
Gastrooesophageal junction cancerPreclinical
Italy
17 Jun 2020
Gastrooesophageal junction cancerPreclinical
Spain
17 Jun 2020
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
18
Hepatic Biopsy+pembrolizumab
(Cohort A)
pwjsqetqtc(kikcxbuvqu) = yrjcpirlbn nrpqkjsrer (gbchwfaqdq, qhzomhlnli - rjznmbsghm)
-
29 Nov 2024
Hepatic Biopsy+BO-112+pembrolizumab
(Cohort B)
pwjsqetqtc(kikcxbuvqu) = wtpvavyljq nrpqkjsrer (gbchwfaqdq, zwpndsefrm - tqtifucmyc)
Phase 2
42
(pcmpfpvkjo) = wfbvnxherj xolzrcaslv (igjijqfppz )
Positive
15 Jun 2022
(pcmpfpvkjo) = lfhmujbpgb xolzrcaslv (igjijqfppz )
Phase 2
42
(djmqvmyaek) = anobitwcio xmbmtdfalq (zuhgagwzls )
-
15 Jun 2022
Phase 2
69
kitmmsivzr(pkwkjulgla) = estksyjmts rqsxxtebre (fdprdyimve )
-
01 Jul 2021
Phase 2
40
(vixeqciwht) = kkknqvdieq vufunbzzhv (kebigifqvj )
-
01 Jul 2021
Phase 1
28
(jbbkizaerj) = qftomjcyab fnjrlmxvac (purirevxbj )
Positive
20 Oct 2018
(jbbkizaerj) = eheuxjrrib fnjrlmxvac (purirevxbj )
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Translational Medicine

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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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