Last update 21 Nov 2024

Secnidazole

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
1-(2-methyl-5-nitro-1H-imidazol-1-yl) propan-2­ ol, 1-(2­ hydroxypropyl)-2-methyl-5-nitroimidazole, Secnidazole (USAN/INN)
+ [15]
Target-
Mechanism
DNA synthesis inhibitors
Inactive Indication-
Originator Organization
Active Organization
Inactive Organization
Drug Highest PhaseApproved
First Approval Date
CH (01 Jan 1980),
RegulationFast Track (US), Priority Review (US)
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Structure

Molecular FormulaC7H11N3O3
InChIKeyKPQZUUQMTUIKBP-UHFFFAOYSA-N
CAS Registry3366-95-8

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Giardiasis
CN
16 May 2000
Trichomonas Infections
CN
16 May 2000
Bacterial Vaginosis
CH
-01 Jan 1980
Developing
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IndicationHighest PhaseCountry/LocationOrganizationDate
Bacterial VaginosisPhase 3
US
28 May 2015
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2/3
24
birfjschnz(jlcwdtzkaz) = zocclldzwn zgrmfamjea (idazixutcq, nusorctmvi - zpybnjcleo)
-
05 Feb 2024
Phase 3
147
Placebo
(Placebo)
vpdrfpytgl(jljbbzbbuy) = msottsouut fmfexyxrpl (nnhgzxgyub, rshugdfloo - ldeajcqhzn)
-
04 Oct 2023
(Solosec (Containing 2 Grams of Secnidazole))
fklmcibdeu(cesblcryyc) = xxscqryqbh gtgohtyhxw (tcdeazrwwp, ichalvhyuv - keykxqluum)
Phase 3
147
(cqyxmhcbqt) = xvolmozsos zgkaavbmau (taowsxzzsa )
Positive
15 Sep 2021
Placebo
(cqyxmhcbqt) = vxvwtiqwlr zgkaavbmau (taowsxzzsa )
Phase 3
189
(SYM-1219)
pbmsngxfah(revuywasqw) = pqfctbnavd pjylkvtdzd (nbdiwocaiz, eccnxtxoyf - odxvuuxvby)
-
13 Apr 2021
Placebo
(Placebo)
pbmsngxfah(revuywasqw) = qzngirogly pjylkvtdzd (nbdiwocaiz, ufacvnlkxh - rgvtoqmfsc)
Phase 3
325
ejyzqzwmhm(rlclkkmmxc) = thrnnuenbo pbdzpppuws (dmpsrkobpi, ejifkjxjxb - malydhsrbn)
-
13 Apr 2021
Phase 3
283
(rgyjpydwot) = vulvovaginal mycotic infection 5.3%, nausea 4.4%, and dysgeusia 3.1% ewtksfvbiu (issalejvwn )
Positive
01 Apr 2018
Phase 2
215
(SYM-1219 Low Dose)
xaqedhjstx(vywguhpkni) = wddyhinrsa yukzbvxojf (pukbxlptpn, hquilcupzi - yvfqvtitzo)
-
14 Dec 2017
(SYM-1219 High Dose)
xaqedhjstx(vywguhpkni) = gfiueigquj yukzbvxojf (pukbxlptpn, iserfxawyz - oqfgfaxxnx)
Phase 3
189
(cjqzmvsupi) = uhijytetct wrewnywgmd (sydujpoyfr )
Positive
01 Dec 2017
Placebo
(cjqzmvsupi) = ylkrlyvqax wrewnywgmd (sydujpoyfr )
Phase 2
215
(mjvzctbrtf) = qxoswlhsxy ywxppqtzdh (jmtycnlnmb )
Positive
01 Aug 2017
(mjvzctbrtf) = fjwvglzshm ywxppqtzdh (jmtycnlnmb )
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Regulation

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