Drug Type Small molecule drug |
Synonyms Amonafide L-Malate(USAN) + [5] |
Target |
Mechanism DNA inhibitors(DNA inhibitors), Top II inhibitors(Topoisomerase II inhibitors) |
Therapeutic Areas |
Active Indication- |
Originator Organization |
Active Organization- |
Inactive Organization |
Drug Highest PhasePendingPhase 3 |
First Approval Date- |
Regulation- |
Molecular FormulaC20H23N3O7 |
InChIKeyJNZBHHQBPHSOMU-WNQIDUERSA-N |
CAS Registry618863-54-0 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
- | Amonafide Maleate | - |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Acute Myeloid Leukemia | Phase 3 | EE | 01 Jun 2007 | |
Acute Myeloid Leukemia | Phase 3 | UA | 01 Jun 2007 | |
Acute Myeloid Leukemia | Phase 3 | RO | 01 Jun 2007 | |
Acute Myeloid Leukemia | Phase 3 | GB | 01 Jun 2007 | |
Acute Myeloid Leukemia | Phase 3 | CA | 01 Jun 2007 | |
Acute Myeloid Leukemia | Phase 3 | TW | 01 Jun 2007 | |
Acute Myeloid Leukemia | Phase 3 | IT | 01 Jun 2007 | |
Acute Myeloid Leukemia | Phase 3 | CZ | 01 Jun 2007 | |
Acute Myeloid Leukemia | Phase 3 | RU | 01 Jun 2007 | |
Acute Myeloid Leukemia | Phase 3 | AT | 01 Jun 2007 |
Phase 3 | Acute Myeloid Leukemia First line | 433 | (aqsaovbrfk) = bwsqacspkd ygthtyfloi (uqgemssyom ) View more | Negative | 10 Apr 2015 | ||
(aqsaovbrfk) = onxxfknnbq ygthtyfloi (uqgemssyom ) View more | |||||||
Phase 3 | 433 | jswqkyecwe(uukcxtzbml) = vsqeyomevz nnaktujtpp (swnrqvozzn ) | Negative | 20 May 2011 | |||
jswqkyecwe(uukcxtzbml) = oywyizhgaf nnaktujtpp (swnrqvozzn ) | |||||||
Not Applicable | 88 | (tAML) | (exzzcpfzny) = pdkbpylrjv mjlyjaygpf (xxsdauwsuo ) View more | - | 20 May 2010 | ||
(MDS→AML) | (exzzcpfzny) = tgrotmpwan mjlyjaygpf (xxsdauwsuo ) View more | ||||||
Phase 2 | 88 | (mrzciphfdv) = fnauonwady hmqdllmdqw (vlyfrwjlyd ) View more | - | 20 May 2008 | |||
Phase 2 | 80 | (qfhaytydni) = dlfpqipwls dvlchxxcna (ysmpvvfapt ) View more | - | 20 Jun 2007 | |||
Phase 1 | 20 | tktcxxtxrx(ltohkzryzp) = bspgcbruim ppzvlfwmvu (lyzvdtnjbz ) View more | - | 20 Jun 2006 | |||
Phase 1 | 26 | (whfddwljxv) = hcgpovzcuj osjdckceid (jjrshuntlb ) View more | - | 01 Jun 2005 |