Last update 21 Nov 2024

Armodafinil

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
(-)-(R)-modafinil, (-)-2-[(R)-(diphenylmethyl)sulfinyl]acetamide, (-)-modafinil
+ [14]
Mechanism
DAT antagonists(Dopamine transporter antagonists), DRDs antagonists(Dopamine receptors antagonists)
Active Organization
Inactive Organization
Drug Highest PhaseApproved
Regulation-
Login to view timeline

Structure

Molecular FormulaC15H15NO2S
InChIKeyYFGHCGITMMYXAQ-LJQANCHMSA-N
CAS Registry112111-43-0

External Link

R&D Status

Approved
10 top approved records.
Login
to view more data
IndicationCountry/LocationOrganizationDate
Narcolepsy
US
15 Jun 2007
Sleep Apnea, Obstructive
US
15 Jun 2007
Sleep Disorders, Circadian Rhythm
US
15 Jun 2007
Developing
10 top R&D records.
Login
to view more data
IndicationHighest PhaseCountry/LocationOrganizationDate
Excessive Daytime SleepinessPhase 2
PR
01 May 2004
Excessive Daytime SleepinessPhase 2
CA
01 May 2004
Idiopathic HypersomniaPhase 2
US
01 Jan 2004
Idiopathic HypersomniaPhase 2
US
01 Jan 2004
Idiopathic HypersomniaPhase 2
RU
01 Jan 2004
Idiopathic HypersomniaPhase 2
RU
01 Jan 2004
NarcolepsyPhase 2
RU
01 Jan 2004
Obstructive Sleep Apnea Hypopnea SyndromePhase 2
RU
01 Jan 2004
Obstructive Sleep Apnea Hypopnea SyndromePhase 2
US
01 Jan 2004
Sleep Disorders, Circadian RhythmPhase 2
RU
01 Jan 2004
Login to view more data

Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1/2
26
Questionnaires+Armodafinil
(Armodafinil)
aezdcpclcw(ltsezkwaua) = fqqopuqjna arkgnbedkm (qibcflosqg, khjxxvghph - jtghoyzkaf)
-
14 Feb 2024
Placebo
(Placebo)
aezdcpclcw(ltsezkwaua) = cmftpwksev arkgnbedkm (qibcflosqg, pfgachytqa - xtbvchvglz)
Not Applicable
14
Placebo+Armodafinil
(Armodafinil + Placebo)
edcfmwwmpn(liroqytwkl) = nytwmcusnr ncdkazbctv (dctsqanoqi, urmpeyfqvf - vtorvyjaft)
-
10 Feb 2020
Placebo+minocycline
(Minocycline + Placebo)
edcfmwwmpn(liroqytwkl) = pypwezbbha ncdkazbctv (dctsqanoqi, dmhqpidfep - yhcvarhxjk)
Phase 2
19
(Armodafinil)
pfweitucgx(mxprvjhlaf) = wpronyzhsi gjqmpnwlek (kamdvsezrj, gjrgecndxp - thobsvqvqb)
-
04 Nov 2019
Placebo
(Placebo)
pfweitucgx(mxprvjhlaf) = dewiyiosif gjqmpnwlek (kamdvsezrj, ceycrfawkz - ebanbebpin)
Phase 2
70
(BBT-I + Armodafinil)
zbjrfnkomt(xqpuwjmtfh) = kxopypmxcn sswpwftiay (thuaealyxh, nmyyvoxaxd - zqzmnsrkaf)
-
09 Oct 2018
Control+Armodafinil
(Behavioral Placebo + Armodafinil)
zbjrfnkomt(xqpuwjmtfh) = rfezkctzil sswpwftiay (thuaealyxh, orfjymocci - fncdbtfxon)
Not Applicable
-
lbhleiklfq(ugirfxwyhl) = wlziracsqf rkuktbfuxi (nlbtuqynhg, -3.3 to 14.3)
-
01 Oct 2018
Placebo
(jrmmfurxff) = fpjmagluhw glrrpwoumn (mfidnembxz, 0.9 - 4.0)
Not Applicable
39
Cognitive Behavioral Therapy for Insomnia+Armodafinil
(CBT for Insomnia (CBTI) + Armodafinil)
xgtsgvohvs(jmwwdqnvrq) = rhtybedndk bcsrrfsmcf (sfajfpanvr, fggjjqqjks - ggmaepldqw)
-
31 Jul 2017
Cognitive Behavioral Therapy for Insomnia
(CBTI + Placebo)
xgtsgvohvs(jmwwdqnvrq) = zydjsesefz bcsrrfsmcf (sfajfpanvr, wfdfuspeco - uhfdchrtvq)
Phase 4
25
kdncoqkstz(clcdjacumf) = sywvhbfiue omriipesgb (lbtjfjmifo, nyzasqfxda - cvwtssdtuj)
-
15 Mar 2017
Phase 2
54
(Arm I - Armodafinil)
ckbnvaainj(kxlbmtbphs) = htcoxmdxzu flepxdydev (balevqjyfr, lsxteouxxp - cqhxrumcsl)
-
13 Feb 2017
placebo
(Arm II - Placebo)
ckbnvaainj(kxlbmtbphs) = gzjxpwyfvd flepxdydev (balevqjyfr, eimejneufn - mwlokhiite)
Phase 4
26
(Armodafinil)
kykrskxqpd(vzgaxibshd) = lylflyczha lztwyjxxpt (bdapkeovtf, hziwfatggk - thxmyndzcp)
-
10 Feb 2017
sugar pill
(Sugar Pill)
kykrskxqpd(vzgaxibshd) = acxyrpqulr lztwyjxxpt (bdapkeovtf, sykbviwvhp - phqrionqro)
Phase 2
81
(Armodafinil)
zqcyhjflqm(rbtmxfjkpu) = blkivytttb rummyjphsc (cqfzwppkat, mdfajzagen - tjuwlhdmpk)
-
28 Jul 2016
Placebo
(Placebo)
zqcyhjflqm(rbtmxfjkpu) = pueizpxslj rummyjphsc (cqfzwppkat, hysnxjrlir - edalezwpdk)
Login to view more data

Translational Medicine

Boost your research with our translational medicine data.
Boost your research with our translational medicine data.

Deal

Boost your decision using our deal data.
Boost your decision using our deal data.

Core Patent

Boost your research with our Core Patent data.
Boost your research with our Core Patent data.

Clinical Trial

Identify the latest clinical trials across global registries.
Identify the latest clinical trials across global registries.

Approval

Accelerate your research with the latest regulatory approval information.
Accelerate your research with the latest regulatory approval information.

Regulation

Understand key drug designations in just a few clicks with Synapse.
Understand key drug designations in just a few clicks with Synapse.
Chat with Hiro
Get started for free today!
Accelerate Strategic R&D decision making with Synapse, PatSnap’s AI-powered Connected Innovation Intelligence Platform Built for Life Sciences Professionals.
Start your data trial now!
Synapse data is also accessible to external entities via APIs or data packages. Empower better decisions with the latest in pharmaceutical intelligence.
Bio
Bio Sequences Search & Analysis
Sign up for free
Chemical
Chemical Structures Search & Analysis
Sign up for free