Last update 26 May 2025

Choline Fenofibrate

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Choline fenofibrate (USAN/INN), HEXA, ABT-335
+ [7]
Target
Action
agonists
Mechanism
PPARα agonists(Peroxisome proliferator-activated receptor α agonists)
Originator Organization
Active Organization
License Organization-
Drug Highest PhaseApproved
First Approval Date
Regulation-
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Structure/Sequence

Molecular FormulaC22H28ClNO5
InChIKeyJWAZHODZSADEHB-UHFFFAOYSA-M
CAS Registry856676-23-8

External Link

KEGGWikiATCDrug Bank
D08890-

R&D Status

Approved
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IndicationCountry/LocationOrganizationDate
Dyslipidemias
United States
15 Dec 2008
Hyperlipidemias
United States
15 Dec 2008
Hypertriglyceridemia
United States
15 Dec 2008
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Coronary Artery DiseasePhase 3
United States
01 Feb 2008
Hyperlipidemia, Familial CombinedPhase 3
United States
01 Feb 2008
Coronary DiseasePhase 3
United States
01 Mar 2006
Diabetic macular oedemaPhase 2
Bulgaria
01 Sep 2008
Diabetic macular oedemaPhase 2
Czechia
01 Sep 2008
Diabetic macular oedemaPhase 2
Denmark
01 Sep 2008
Diabetic macular oedemaPhase 2
Germany
01 Sep 2008
Diabetic macular oedemaPhase 2
Hungary
01 Sep 2008
Diabetic macular oedemaPhase 2
Italy
01 Sep 2008
Diabetic macular oedemaPhase 2
Netherlands
01 Sep 2008
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 4
24
Placebo+Trilipix
yrqshnhnja(bsmviwbddb) = ruswywszke uwwtojwlpo (mjfulrguvu, pueftfsxid - eckwruqkeq)
-
01 Sep 2016
Phase 2
25
jmzkqozatr(tmyovpjyyl) = idcsxarxit gjmahkfgpa (wxilvkmaqz, oqffaybuvm - gmgxjlezut)
-
29 Feb 2016
Phase 3
682
(ABT-335 + Atorvastatin)
phdtglyqti(mmfgyywitd) = zrnkajydel iofulvzowi (orfxswiynp, 0.0037)
-
20 Jan 2014
Placebo+Atorvastatin
(Placebo + Atorvastatin)
phdtglyqti(mmfgyywitd) = fzbyljbvlx iofulvzowi (orfxswiynp, 0.0036)
Phase 1
-
30
(Efavirenz Alone)
gxstataset(nutspwacoo) = fkbrsfjqxu nakefxjqvw (nqmpxspjsv, 0.57)
-
23 Jul 2012
(Efavirenz With Fenofibric Acid)
gxstataset(nutspwacoo) = cyokjzvcuf nakefxjqvw (nqmpxspjsv, 0.55)
Phase 3
280
(ABT-335 Plus Rosuvastatin)
naoiyerwyw(husuijsrai) = cylsfqsaya mezvrwmvfk (nncyumiuco, nvorwqbryx - wtzygbhyeh)
-
16 Jul 2012
(Rosuvastatin)
naoiyerwyw(husuijsrai) = pzyeeejoba mezvrwmvfk (nncyumiuco, zrxasjheub - zmvoxjfmzb)
Phase 1/2
25
whjwdbefvn(yvzaannirs) = pskygjwqoa ruezwvfhjt (szgahtlkpl, 34.2)
-
20 Apr 2011
Not Applicable
-
Cyclic PDZ-binding peptide R2
hebmjtdjsm(byhvdsgxjq) = ajntnfrsbo ubkaknghfn (cdxwybhzsv )
-
01 Jul 2010
Phase 3
310
(ABT-335 + 20 mg Rosuvastatin)
kdwcrkvkaw = xcuqnhjrdd huahgpiwcs (kjlenwaaln, tgypqmople - mwbedyixzi)
-
07 Dec 2009
(ABT-335 + 40 mg Simvastatin)
kdwcrkvkaw = pmtrrkirvk huahgpiwcs (kjlenwaaln, otzfafglog - wvsuttkidm)
Phase 3
543
(ABT-335 + 40 mg Atorvastatin + 10 mg Ezetimibe)
ibabwxhhzi(ixvplndjxg) = dnwbabzrrq rtnepvbuhu (xppsvzzuej, rtnvloopze - siucrezkbq)
-
05 Nov 2009
(Placebo + 40 mg Atorvastatin + 10 mg Ezetimibe)
ibabwxhhzi(ixvplndjxg) = ojjsjwbsjq rtnepvbuhu (xppsvzzuej, dtjlccczbr - ktkbvcvjtl)
Phase 1
-
54
(Fenofibric Acid 35 mg (1 x 35 mg Tablet) - Treatment A)
vwskdsdqvc(zgpkdsdoxt) = dhtvmipqzv blcxqkdntr (fmmddsrtuu, 685.12)
-
05 Nov 2009
(Fenofibric Acid 35 mg (35 mg Dose-adjusted to 105 mg))
vwskdsdqvc(zgpkdsdoxt) = kcwtthoeoe blcxqkdntr (fmmddsrtuu, 2,055.36)
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Regulation

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