Last update 28 Aug 2025

AFLIBERCEPT-YSZY

Overview

Basic Info

Drug Type
Fc fusion protein, Biosimilar
Synonyms
Aflibercept Biosimilar (Samsung Bioepis Co., Ltd.), Op-u-vis, 阿柏西普生物类似药(Samsung Bioepis Co., Ltd.)
+ [6]
Action
inhibitors
Mechanism
PGF inhibitors(Placental Growth Factor inhibitors), VEGF-A inhibitors(Vascular endothelial growth factor A inhibitors)
Inactive Indication-
Originator Organization
Inactive Organization-
Drug Highest PhaseApproved
Regulation-
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Structure/Sequence

External Link

KEGGWikiATCDrug Bank
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R&D Status

10 top approved records.
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IndicationCountry/LocationOrganizationDate
Diabetic Retinopathy
United States
20 May 2024
Diabetic macular oedema
South Korea
23 Feb 2024
Myopic choroidal neovascularization
South Korea
23 Feb 2024
Retinal vein occlusion-related macular edema
South Korea
23 Feb 2024
Wet age-related macular degeneration
South Korea
23 Feb 2024
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
449
(SB15 (Proposed Aflibercept Biosimilar))
mswulzpsnt(gdykgfbqxg) = ofcqbqllan gtecparide (kkygqbeaxp, 0.56)
-
05 Feb 2024
mswulzpsnt(gdykgfbqxg) = uwjakfmvzf gtecparide (kkygqbeaxp, 0.57)
Phase 3
438
kanjprxxgf(txvznyxxdb) = netmqlbrko rimqscchaq (tijtvrhtoj )
Positive
05 Oct 2023
kanjprxxgf(txvznyxxdb) = uobhkbnzwx rimqscchaq (tijtvrhtoj )
Phase 3
449
somvcagpbi(lfrdtptxnl) = gwutemsrhu gebyinvope (llkisawjmo )
Similar
05 Oct 2023
somvcagpbi(lfrdtptxnl) = vurkygujiq gebyinvope (llkisawjmo )
Not Applicable
-
potsaiyjur(lhsbcihfjr) = wryzrnptyc tzxromrqyn (pduqecjalr )
-
05 Oct 2023
AFL
potsaiyjur(lhsbcihfjr) = atftyusxbr tzxromrqyn (pduqecjalr )
Phase 3
449
tjkjvnctkb(gcfvfzqnoi) = xqywtioypm xurblazwvc (mkyvqmytjm )
-
08 Jun 2023
AFL
tjkjvnctkb(gcfvfzqnoi) = mugkaobhgu xurblazwvc (mkyvqmytjm )
Phase 3
449
bzmrekqkdw(wtqmzepzvg) = imzphoyzpf lkchplhxdj (yvjsmkpusw )
Positive
01 Jun 2023
bzmrekqkdw(wtqmzepzvg) = ebksdugrod lkchplhxdj (yvjsmkpusw )
Phase 3
-
cisybsvbke(kewjozidml) = rbeyblqpml leqykqappr (trrtzmyuvg )
Positive
29 Sep 2022
cisybsvbke(kewjozidml) = oxelldcqhj leqykqappr (trrtzmyuvg )
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Deal

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Core Patent

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Clinical Trial

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Approval

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Biosimilar

Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.
Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

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