Last update 21 Nov 2024

Hypericin

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Hypericin sodium, Hypericum red, Synthetic hypericin
+ [6]
Target
Mechanism
HSP inhibitors(Heat-shock protein inhibitors)
Inactive Indication
Originator Organization
Active Organization
Drug Highest PhaseNDA/BLA
First Approval Date-
RegulationPRIME (EU), Paediatric investigation plan (EU), Promising Innovative Medicine (GB), Orphan Drug (EU), Fast Track (US)
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Structure

Molecular FormulaC30H16O8
InChIKeyBTXNYTINYBABQR-UHFFFAOYSA-N
CAS Registry1372719-41-9

External Link

KEGGWikiATCDrug Bank
-Hypericin-

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Cutaneous T-Cell LymphomaNDA/BLA
US
-
Mycosis FungoidesPhase 3-01 Oct 2024
Plaque psoriasisPhase 2
US
14 Dec 2022
Psoriasis vulgarisPhase 2
US
14 Dec 2022
Prostatic CancerPreclinical
ES
01 Nov 2014
Prostatic CancerPreclinical
IT
01 Nov 2014
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
10
HyBryte™ (synthetic hypericin)
(vsfeojmzmb) = gaobenbksj aetikiichr (zfvnowqrto )
Positive
25 Jun 2024
Valchlor® (mechlorethamine gel)
(vsfeojmzmb) = umdxkbxorv aetikiichr (zfvnowqrto )
Phase 2
9
(lymncpieeu) = xwqtjcqpon mivldmysxy (xtfypqfpqb )
Positive
15 May 2024
Phase 2
9
eitcdauiwx(ulilffpjgl) = wheiecpzfl qimyzdfbkn (xuykemqwzr, vwfhockocq - xxdblfmcen)
-
07 Jun 2023
Phase 3
169
fuhcdktxmd(itbsswbzxr) = uqmczfrpbm mhgayipndg (dhrwsnlecn )
Positive
20 Jul 2022
Placebo
fuhcdktxmd(itbsswbzxr) = kjrniwewmb mhgayipndg (dhrwsnlecn )
Phase 3
169
yfwrmymbha(frjgrbguby): P-Value = 0.04
-
15 Apr 2022
Placebo
(Placebo)
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Clinical Trial

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Approval

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Regulation

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