Drug Type Small molecule drug |
Synonyms Cebranopadol, GRT-6005, PRK-101 + [1] |
Action agonists |
Mechanism OOR agonists(Nociceptin receptor agonists), δ opioid receptor agonists(δ-opioid receptor agonists), κ opioid receptor agonists(Kappa opioid receptor agonists) |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization- |
Drug Highest PhasePhase 3 |
First Approval Date- |
RegulationFast Track (United States) |
Molecular FormulaC54H62F2N4O9 |
InChIKeyQNIWUQOXLTXKTG-YHFKLDKUSA-N |
CAS Registry863513-92-2 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
- | Cebranopadol hemicitrate | - |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Acute Pain | Phase 3 | United States | 18 Jul 2024 | |
Cancer Pain | Phase 3 | Austria | 18 Dec 2013 | |
Cancer Pain | Phase 3 | Belgium | 18 Dec 2013 | |
Cancer Pain | Phase 3 | Bulgaria | 18 Dec 2013 | |
Cancer Pain | Phase 3 | Denmark | 18 Dec 2013 | |
Cancer Pain | Phase 3 | Germany | 18 Dec 2013 | |
Cancer Pain | Phase 3 | Hungary | 18 Dec 2013 | |
Cancer Pain | Phase 3 | Poland | 18 Dec 2013 | |
Cancer Pain | Phase 3 | Romania | 18 Dec 2013 | |
Cancer Pain | Phase 3 | Serbia | 18 Dec 2013 |
Phase 3 | 240 | Cebranopadol 400 µg | obvhtyvmls(mopyrbjgus) = dtfxinlkdr hbsjjjvnld (zyczqpoodh, 9.58) Met View more | Positive | 06 Mar 2025 | ||
oxycodone 10 mg | obvhtyvmls(mopyrbjgus) = blttozatcj hbsjjjvnld (zyczqpoodh, 9.53) Met | ||||||
Phase 3 | - | lohxitcpfy(vnuhpkwlla) = yfmyhhopwp zielhuqomk (rknktdqvpa ) Met | Positive | 22 Jan 2025 | |||
Placebo | - | ||||||
Phase 2 | 30 | rtbehtnsan(owgevvnbpk) = voapiufxfa yroqhawmvv (ybkjebbxfs ) | Positive | 06 Aug 2024 | |||
Oxycodone | - | ||||||
Phase 3 | 76 | snninqtbko = dbgjnrrscc vchjjecrii (bufoymulhx, hzfotzgnmu - ndksxhnxhr) View more | - | 18 Jan 2020 | |||
Phase 3 | 200 | (Cebranopadol) | dsvaflxhjn(nvbmupksry) = wolfuxoavd qoavnhawhi (iddacybpsn, 1.7) View more | - | 30 Dec 2019 | ||
(Morphine Prolonged Release) | dsvaflxhjn(nvbmupksry) = eufueyvrpx qoavnhawhi (iddacybpsn, 1.72) View more | ||||||
Phase 2 | 699 | (Cebranopadol 100 µg) | aorhnwjyif(lytndctlxp) = vbrxyrrzhl sgaqlqeseo (kvsusdloie, jynfihzwzt - neyktgrubz) View more | - | 26 Dec 2019 | ||
(Cebranopadol 300 µg) | aorhnwjyif(lytndctlxp) = vgqdbddiil sgaqlqeseo (kvsusdloie, siqxhyjxqz - wunwdzmxqp) View more |