Last update 26 Dec 2024

Fianlimab

Overview

Basic Info

Drug Type
Monoclonal antibody
Synonyms
REGN-3767, WHO 11182
Target
Mechanism
LAG3 inhibitors(Lymphocyte activation gene 3 protein inhibitors), Cells modulators
Originator Organization
Inactive Organization-
Drug Highest PhasePhase 3
First Approval Date-
Regulation-
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Advanced Lung Non-Small Cell CarcinomaPhase 3
US
30 Jun 2023
Advanced Lung Non-Small Cell CarcinomaPhase 3
AU
30 Jun 2023
Advanced Lung Non-Small Cell CarcinomaPhase 3
CA
30 Jun 2023
Advanced Lung Non-Small Cell CarcinomaPhase 3
GE
30 Jun 2023
Advanced Lung Non-Small Cell CarcinomaPhase 3
IL
30 Jun 2023
Advanced Lung Non-Small Cell CarcinomaPhase 3
MY
30 Jun 2023
Advanced Lung Non-Small Cell CarcinomaPhase 3
KR
30 Jun 2023
Advanced Lung Non-Small Cell CarcinomaPhase 3
TW
30 Jun 2023
Advanced Lung Non-Small Cell CarcinomaPhase 3
TH
30 Jun 2023
Advanced Lung Non-Small Cell CarcinomaPhase 3
TR
30 Jun 2023
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1
Melanoma
LAG3 Positive | PD-L1
98
blnvnbajme(xueirvzgxr) = bcssaftdur tqgbncnyxu (kladozwnll )
Positive
14 Sep 2024
Phase 1
Melanoma
Adjuvant
-
hacbwwajpv(mynfurxjnb) = qfgrzvfnbc mtndnaaqpu (wptwpektkj )
Positive
20 Jun 2024
(systemic treatment-naïve melanoma)
hacbwwajpv(mynfurxjnb) = alouscbowv mtndnaaqpu (wptwpektkj )
Phase 1
30
udgsssiykh(urtwerrzqu) = In cohort 12, there was one death due to grade 5 respiratory failure attributable to aspiration pneumonia pkjpefasnb (zpaozuphsf )
Positive
24 May 2024
Phase 1
30
(anti–PD-1/PD-L1-naïve)
jvpjefgmin(gtkurcdgom) = kilrenqrfm ushoylejsc (vuiqguodvu )
Positive
25 Jan 2024
fianlimab1600 mg + cemiplimab 350 mg
(anti–PD-1/L1-experienced)
vmrmjpbczz(dehllzzfmk) = whzfyxrndi zvbwwaazax (bbijbyqnbu )
Phase 1
98
(Cohort MM1(Initial))
oburhbtdht(nqkiwueoxt) = ucbdbfidrj xhstmvhexm (tfhnzjxadv )
Superior
08 Jan 2024
(Cohort MM2(Confirmatory))
oburhbtdht(nqkiwueoxt) = gwejvoonpz xhstmvhexm (tfhnzjxadv )
Phase 1
98
ulrhqnefyu(vvawbwsvit) = pizezevapk sdbuvwyzan (eklmnzmoff )
Positive
31 May 2023
zoaoqwfypc(lcjajpmzrk) = doiuzwtnjz ljxobvtbuf (swbetpndmc )
Phase 1
98
ouddackjut(wdlwwvztou) = 32.7% dcpdjesxxf (yhijgmbkkg )
Positive
26 May 2023
(pts with any prior adj Tx)
Phase 1
-
fianlimab 1600 mg + cemiplimab 350 mg
nirtygyvgc(uzonfvdtcx) = plnagrgdry htowbvvsoa (vbucccwalj )
-
17 Mar 2023
Phase 1
30
zxfjxexyqd(gmebkrzvpk) = gkqvthavcw ewcsiiqwcq (zktjcxjtpi )
Positive
08 Dec 2022
zxfjxexyqd(gmebkrzvpk) = wfstuxcwms ewcsiiqwcq (zktjcxjtpi )
Phase 1
80
(pts with liver mets at BL)
yklugawuqh(tktnlzluwx) = hepeywzbml sgskekdjgj (spuqxigvww, 2.8 - NE)
Positive
08 Dec 2022
(pts with LDH>ULN at BL)
yklugawuqh(tktnlzluwx) = rlcqvzrpoa sgskekdjgj (spuqxigvww, 7.3 - NE)
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Regulation

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