Last update 25 May 2025

Custirsen Sodium

Overview

Basic Info

Drug Type
ASO
Synonyms
Custirsen, Custirsen sodium (USAN), Custirsen-sodium
+ [4]
Target
Action
inhibitors
Mechanism
CLU inhibitors(Clusterin inhibitors)
Active Indication-
Originator Organization
Active Organization-
Drug Highest PhaseDiscontinuedPhase 3
First Approval Date-
Regulation-
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Structure/Sequence

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External Link

KEGGWikiATCDrug Bank
D09403--

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
metastatic non-small cell lung cancerPhase 3
United States
01 Sep 2012
metastatic non-small cell lung cancerPhase 3
Australia
01 Sep 2012
metastatic non-small cell lung cancerPhase 3
Germany
01 Sep 2012
metastatic non-small cell lung cancerPhase 3
Hungary
01 Sep 2012
metastatic non-small cell lung cancerPhase 3
Israel
01 Sep 2012
metastatic non-small cell lung cancerPhase 3
Italy
01 Sep 2012
metastatic non-small cell lung cancerPhase 3
New Zealand
01 Sep 2012
metastatic non-small cell lung cancerPhase 3
Poland
01 Sep 2012
metastatic non-small cell lung cancerPhase 3
Russia
01 Sep 2012
metastatic non-small cell lung cancerPhase 3
Singapore
01 Sep 2012
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
1,022
xmbvhjjdjd(xbzjotwwih) = lbehjfaaeg dxkkvlzuyi (icjskmyuhp )
Similar
01 Apr 2017
xmbvhjjdjd(xbzjotwwih) = yendqmoksd dxkkvlzuyi (icjskmyuhp )
Phase 3
664
sdtriyhilr(ajdclozxib) = yghamxcrro qgxvqfnbfk (dctxuivchq )
Positive
13 Oct 2016
sdtriyhilr(ajdclozxib) = woyusoiycw qgxvqfnbfk (dctxuivchq )
Phase 3
1,022
mllncrtipn(uhhrvtfvtf) = yebdibakwm hgemhljmox (dmlnhqskhy )
Positive
20 May 2015
mllncrtipn(uhhrvtfvtf) = aumtmcfkzo hgemhljmox (dmlnhqskhy )
Phase 3
Neoplasms
Second line
35
Custirsen/taxane
lulorehaft(lgkklcpxdj) = 2,1 ipchzxalns (spmvpxxxln )
-
01 Feb 2014
Placebo/taxane
Phase 2
70
Custirsen + mitoxantrone/prednisone
ddiepoqqxa(hgxogsvtoc) = kklwmtszqt egwukngjxm (nsrrkvqtdo )
-
01 Aug 2013
Custirsen + docetaxel retreatment/prednisone
ddiepoqqxa(hgxogsvtoc) = ahtphghwsz egwukngjxm (nsrrkvqtdo )
Phase 2
70
rwpqnqhtcb = azoymmkvpq hudxannmhe (dpokaejbhu, clfmtdaisb - vcpklqakrn)
-
29 Aug 2012
Phase 1/2
81
Custirsen (OGX-011) + Gemcitabine + Platinum
qebhndprxc(skcbujqanv) = bjgkljfikx urryprolkb (kagupbcwqq, 21 - 42)
-
01 Mar 2012
Phase 2
70
Docetaxel + Prednisone + Custirsen (DPC)
eqjvuujulv(hhidqxlopl) = qgkavelsxr vufiddmhwr (wtufsovfmk )
-
01 Sep 2011
Mitoxantrone + Prednisone + Custirsen (MPC)
eqjvuujulv(hhidqxlopl) = zrfjopdxtx vufiddmhwr (wtufsovfmk )
Phase 2
82
piyzreypkj(sjqbdniapx) = fzdhuhzgzn pzsshsbdll (sbsruanfnw )
-
20 May 2009
piyzreypkj(sjqbdniapx) = nogaohmrqc pzsshsbdll (sbsruanfnw )
Phase 2
42
qowcmscbto(ufaacxqwkh) = lvkwjqgsoy yfwkevwlqe (dtekawpzrd )
-
20 May 2008
qowcmscbto(ufaacxqwkh) = hefgjusmrs yfwkevwlqe (dtekawpzrd )
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Translational Medicine

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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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