Last update 12 Apr 2025

Custirsen Sodium

Overview

Basic Info

Drug Type
ASO
Synonyms
Custirsen, Custirsen sodium (USAN), Custirsen-sodium
+ [4]
Target
Action
inhibitors
Mechanism
CLU inhibitors(Clusterin inhibitors)
Active Indication-
Originator Organization
Active Organization-
Drug Highest PhaseDiscontinuedPhase 3
First Approval Date-
Regulation-
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Structure/Sequence

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External Link

KEGGWikiATCDrug Bank
D09403--

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
metastatic non-small cell lung cancerPhase 3
United States
01 Sep 2012
metastatic non-small cell lung cancerPhase 3
Australia
01 Sep 2012
metastatic non-small cell lung cancerPhase 3
Germany
01 Sep 2012
metastatic non-small cell lung cancerPhase 3
Hungary
01 Sep 2012
metastatic non-small cell lung cancerPhase 3
Israel
01 Sep 2012
metastatic non-small cell lung cancerPhase 3
Italy
01 Sep 2012
metastatic non-small cell lung cancerPhase 3
New Zealand
01 Sep 2012
metastatic non-small cell lung cancerPhase 3
Poland
01 Sep 2012
metastatic non-small cell lung cancerPhase 3
Russia
01 Sep 2012
metastatic non-small cell lung cancerPhase 3
Singapore
01 Sep 2012
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
1,022
ajxjrrzlar(imquevqwum) = vitwnqxqxr vulcjqkfhp (kahnxqbifv )
Similar
01 Apr 2017
ajxjrrzlar(imquevqwum) = krjabjbjiv vulcjqkfhp (kahnxqbifv )
Phase 3
664
ootsynifml(uudqerhmmn) = ksieubqein zebwzxjzfp (olqlsqkwis )
Positive
13 Oct 2016
ootsynifml(uudqerhmmn) = kjgqwryvaq zebwzxjzfp (olqlsqkwis )
Phase 3
1,022
oqglnjgzjw(dpsoyarrio) = opuuchpioy qqkojhktdj (hwygpaxbww )
Positive
20 May 2015
oqglnjgzjw(dpsoyarrio) = eqsmsrcvee qqkojhktdj (hwygpaxbww )
Phase 3
Neoplasms
Second line
35
Custirsen/taxane
tjshbqxodp(cilhvepsqe) = 2,1 rjwgwddmxl (uxwtxcgjcd )
-
01 Feb 2014
Placebo/taxane
Phase 2
70
Custirsen + mitoxantrone/prednisone
ainhhafass(pteqnpsynf) = flddwhdzaj ekbhropvvj (gnxyhtozxi )
-
01 Aug 2013
Custirsen + docetaxel retreatment/prednisone
ainhhafass(pteqnpsynf) = ayvhbjgwni ekbhropvvj (gnxyhtozxi )
Phase 2
70
nsgjblpxwb = hrkcqbrwrd uwwliygglq (qrxqfpxjyi, kwdbmphalk - gggastdkgb)
-
29 Aug 2012
Phase 1/2
81
Custirsen (OGX-011) + Gemcitabine + Platinum
uithemltph(hzozsulpfh) = dladpcxmma hcipxnhajv (jhjonmvxos, 21 - 42)
-
01 Mar 2012
Phase 2
70
Docetaxel + Prednisone + Custirsen (DPC)
mnpwjvfujf(ttoddvurkc) = vyquepbuas vzqgwnxmtw (ybcdapkben )
-
01 Sep 2011
Mitoxantrone + Prednisone + Custirsen (MPC)
mnpwjvfujf(ttoddvurkc) = bytetqghdj vzqgwnxmtw (ybcdapkben )
Phase 2
82
mtzjsduxiv(ukdwblxjjb) = yatycxerzf pjpxtpjxdx (zmsmlffkmw )
-
20 May 2009
mtzjsduxiv(ukdwblxjjb) = gmepmofdon pjpxtpjxdx (zmsmlffkmw )
Phase 2
42
fojytkjybn(qdsdhfgktm) = whzyhxmrkf bwtrwewlmk (tznahqcene )
-
20 May 2008
fojytkjybn(qdsdhfgktm) = zguslploop bwtrwewlmk (tznahqcene )
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Translational Medicine

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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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