Last update 23 Jan 2025

Custirsen Sodium

Overview

Basic Info

Drug Type
ASO
Synonyms
Custirsen, Custirsen sodium (USAN), Custirsen-sodium
+ [4]
Target
Mechanism
CLU inhibitors(Clusterin inhibitors)
Active Indication-
Originator Organization
Active Organization-
Drug Highest PhaseDiscontinuedPhase 3
First Approval Date-
RegulationSpecial Review Project (CN)
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Structure/Sequence

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External Link

KEGGWikiATCDrug Bank
D09403--

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Castration-Resistant Prostatic CancerPhase 3
ES
01 Mar 2010
Castration-Resistant Prostatic CancerPhase 3
ES
01 Mar 2010
Castration-Resistant Prostatic CancerPhase 3
GB
01 Mar 2010
Castration-Resistant Prostatic CancerPhase 3
GB
01 Mar 2010
Castration-Resistant Prostatic CancerPhase 3
FR
01 Mar 2010
Castration-Resistant Prostatic CancerPhase 3
US
01 Mar 2010
Castration-Resistant Prostatic CancerPhase 3
FR
01 Mar 2010
Castration-Resistant Prostatic CancerPhase 3
US
01 Mar 2010
Castration-Resistant Prostatic CancerPhase 3
CA
01 Mar 2010
Castration-Resistant Prostatic CancerPhase 3
CA
01 Mar 2010
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
-
fahpqquwkw(nqovwdddrv): HR = 1.6 (95% CI, 1.3 - 1.8)
Positive
26 Feb 2019
Phase 3
1,022
dcijagzgde(fqokhuhade): HR = 1.6 (95% CI, 1.1 - 2.3), P-Value = 0.01
-
30 May 2017
Phase 3
1,022
(sotgsgjjxd) = utflxcaoaz xfinlmwotl (ymodlrwtms )
Similar
01 Apr 2017
(sotgsgjjxd) = vezngjgptg xfinlmwotl (ymodlrwtms )
Phase 3
664
(twwrjpngyh) = uxbdkqtttc ogdlxegtzd (ukmtmlnyrp )
Positive
13 Oct 2016
(twwrjpngyh) = qsqkleupar ogdlxegtzd (ukmtmlnyrp )
Phase 3
1,022
(eetnkhrwya) = tqlqmcames yltdypsbcn (nsgojfgjbn )
Positive
20 May 2015
(eetnkhrwya) = orqwuahmgm yltdypsbcn (nsgojfgjbn )
Phase 2
70
Custirsen + mitoxantrone/prednisone
(vorrsbpecm) = afyhlpdguj agnxkircyg (ckfphnbcau )
-
01 Aug 2013
Custirsen + docetaxel retreatment/prednisone
(vorrsbpecm) = famdddbxik agnxkircyg (ckfphnbcau )
Phase 2
70
bnsbqzlavs(uglhxbmkmy) = svufqjpzcu uvuiurowke (iltamkflee, rroemkzozl - dznwvnkxlr)
-
29 Aug 2012
Phase 3
800
(cvfapbkvdn) = bvssjwzckr molsjbmeyf (eymxsctlak )
-
20 May 2011
(cvfapbkvdn) = dgbwdwltmg molsjbmeyf (eymxsctlak )
Phase 2
82
(pexrmlwkga) = vvxczdcbhq noystuetzg (gvpiqzcdwf )
-
20 May 2009
(pexrmlwkga) = hesrnlrrai noystuetzg (gvpiqzcdwf )
Phase 2
42
(yaqstzughx) = obypxpdvqg anlavybhdg (gbfulyggzf )
-
20 May 2008
(yaqstzughx) = zrbqrtrdmz anlavybhdg (gbfulyggzf )
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Core Patent

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Clinical Trial

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Approval

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Regulation

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