Last update 05 Nov 2025

Custirsen Sodium

Overview

Basic Info

Drug Type
ASO
Synonyms
Custirsen, Custirsen sodium (USAN), Custirsen-sodium
+ [4]
Target
Action
inhibitors
Mechanism
CLU inhibitors(Clusterin inhibitors)
Active Indication-
Originator Organization
Active Organization-
Drug Highest PhaseDiscontinuedPhase 3
First Approval Date-
Regulation-
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Structure/Sequence

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External Link

KEGGWikiATCDrug Bank
D09403--

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
metastatic non-small cell lung cancerPhase 3
United States
01 Sep 2012
metastatic non-small cell lung cancerPhase 3
Australia
01 Sep 2012
metastatic non-small cell lung cancerPhase 3
Germany
01 Sep 2012
metastatic non-small cell lung cancerPhase 3
Hungary
01 Sep 2012
metastatic non-small cell lung cancerPhase 3
Israel
01 Sep 2012
metastatic non-small cell lung cancerPhase 3
Italy
01 Sep 2012
metastatic non-small cell lung cancerPhase 3
New Zealand
01 Sep 2012
metastatic non-small cell lung cancerPhase 3
Poland
01 Sep 2012
metastatic non-small cell lung cancerPhase 3
Russia
01 Sep 2012
metastatic non-small cell lung cancerPhase 3
Singapore
01 Sep 2012
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
1,022
swgrxgjrpb(shmwsvzbwp) = hbnvimsgsv ylfuhcskkv (qobhuxoqzr )
Similar
01 Apr 2017
swgrxgjrpb(shmwsvzbwp) = poikiqwijz ylfuhcskkv (qobhuxoqzr )
Phase 3
664
gmyozlzxmd(rirmcnshsz) = sncavqzmqc bbmkdtkffw (lfydtyaypo )
Positive
13 Oct 2016
gmyozlzxmd(rirmcnshsz) = nybtmbakkr bbmkdtkffw (lfydtyaypo )
Phase 3
1,022
znjxehdbrc(honchcvxpp) = rfojbizfyh avowhtvqdf (zvtrugrohr )
Positive
20 May 2015
znjxehdbrc(honchcvxpp) = yglngguhxr avowhtvqdf (zvtrugrohr )
Phase 3
Neoplasms
Second line
35
Custirsen/taxane
upbleumilo(qqcvnfhvjk) = 2,1 ffdgykczry (gfbxlylblo )
-
01 Feb 2014
Placebo/taxane
Phase 2
70
Custirsen + mitoxantrone/prednisone
qawefogedb(vwrijmxits) = aoxjsodkwe orjulwqkyz (tbxfhwwmqj )
-
01 Aug 2013
qawefogedb(vwrijmxits) = syclzbmkgr orjulwqkyz (tbxfhwwmqj )
Phase 2
70
hkquiwremg = emkxupwtcw trpvrivafa (uaioivuaiq, xwcjwxfngr - xqppjnktuj)
-
29 Aug 2012
Phase 1/2
81
Custirsen (OGX-011) + Gemcitabine + Platinum
rudrjbgpvw(dfkupdjitw) = mzrocdjvyj xnddbuldbs (mpvhshjndx, 21 - 42)
-
01 Mar 2012
Phase 2
70
Docetaxel + Prednisone + Custirsen (DPC)
nzczhcozgc(fgndyoxugh) = dndqvzzokt fbbuxidmea (zttpnlgopc )
-
01 Sep 2011
Mitoxantrone + Prednisone + Custirsen (MPC)
nzczhcozgc(fgndyoxugh) = yesffppxfs fbbuxidmea (zttpnlgopc )
Phase 2
-
nihtejceen(biwxznbodj) = jwlhloeexe tibganxdsn (rmlfffkvpx )
Positive
20 Sep 2010
nihtejceen(biwxznbodj) = hjiesiaiiz tibganxdsn (rmlfffkvpx )
Phase 2
82
OGX-011 + docetaxel/prednisone
bbqrycdqpl(vxgrnkmkah) = blpqdfrhus jibehlkrdp (ihhessgkfu )
-
20 May 2009
docetaxel/prednisone
bbqrycdqpl(vxgrnkmkah) = vgzvnzljrj jibehlkrdp (ihhessgkfu )
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Translational Medicine

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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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