Last update 01 Nov 2024

Flotetuzumab

Overview

Basic Info

Drug Type
Bispecific T-cell Engager (BiTE)
Synonyms
Anti-CD123/CD3-monoclonal-antibody-MGD006, CD123 x CD3(MacroGenics/Servier), CD123xCD3-DART-bispecific-antibody-MGD006
+ [8]
Mechanism
CD123 inhibitors(Interleukin-3 receptor subunit alpha inhibitors), CD3 stimulants(T cell surface glycoprotein CD3 stimulants)
Originator Organization
Inactive Organization
Drug Highest PhasePhase 2
First Approval Date-
RegulationOrphan Drug (US)
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External Link

KEGGWikiATCDrug Bank
D11306Flotetuzumab-

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
High Risk Myelodysplastic SyndromePhase 3
ES
09 Jun 2014
High Risk Myelodysplastic SyndromePhase 3
NL
09 Jun 2014
High Risk Myelodysplastic SyndromePhase 3
IT
09 Jun 2014
Acute Myeloid LeukemiaPhase 2--
Myelodysplastic SyndromesPhase 2--
High Risk Myelodysplastic SyndromePreclinical
FR
09 Jun 2014
High Risk Myelodysplastic SyndromePreclinical
GB
09 Jun 2014
High Risk Myelodysplastic SyndromePreclinical
IL
09 Jun 2014
High Risk Myelodysplastic SyndromePreclinical
DE
09 Jun 2014
Myelodysplastic SyndromesPreclinical--
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1/2
88
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Positive
11 Feb 2021
Not Applicable
-
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-
14 Jun 2019
rpnuagnovx(zcsxhqolpz) = zeeuwhhuom wwemvzwsju (xwbmrgkhjw )
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Approval

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Regulation

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