Last update 30 Mar 2025

Articaine Hydrochloride/Epinephrine Bitartrate

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Articaine Hydrochloride and Epinephrine Tartrate, Compound Articaine Hydrochloride, 复方盐酸阿替卡因
+ [8]
Action
agonists, modulators
Mechanism
ADRA1 agonists(Adrenergic receptor alpha-1 agonists), SCNA modulators(Sodium channel alpha subunit modulators), β-adrenoceptors agonists(Beta adrenergic receptors agonists)
Therapeutic Areas
Active Indication
Inactive Indication
Originator Organization
Inactive Organization-
Drug Highest PhaseApproved
First Approval Date
Germany (01 Jan 1976),
Regulation-
Login to view timeline

Structure/Sequence

Molecular FormulaC13H21ClN2O3S
InChIKeyGDWDBGSWGNEMGJ-UHFFFAOYSA-N
CAS Registry23964-57-0
View All Structures (2)

External Link

KEGGWikiATCDrug Bank
---

R&D Status

Approved
10 top approved records.
Login
to view more data
IndicationCountry/LocationOrganizationDate
Anesthesia
Germany
01 Jan 1976
Developing
10 top R&D records.
Login
to view more data
IndicationHighest PhaseCountry/LocationOrganizationDate
Inflammatory painPreclinical
United States
--
Login to view more data

Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
-
4% articaine with epinephrine 1:100,000
nryikqniwo(nnoqgfqurl) = IANB with 4% articaine and epinephrine 1:100,000 did not have any significant change in PBF for the first 20 min post injection in mandibular first molars, and for 45 min post injection in the canines. However, a hyperemic response occurred during 25-60 min post injection in the molars, and between 60 and 75 min post injection in the canines. Thereafter, the PBF in both teeth returned to the baseline. ucvzdolxkx (ecveuhmvvw )
-
01 Jan 2021
Login to view more data

Translational Medicine

Boost your research with our translational medicine data.
Boost your research with our translational medicine data.

Deal

Boost your decision using our deal data.
Boost your decision using our deal data.

Core Patent

Boost your research with our Core Patent data.
Boost your research with our Core Patent data.

Clinical Trial

Identify the latest clinical trials across global registries.
Identify the latest clinical trials across global registries.

Approval

Accelerate your research with the latest regulatory approval information.
Accelerate your research with the latest regulatory approval information.

Regulation

Understand key drug designations in just a few clicks with Synapse.
Understand key drug designations in just a few clicks with Synapse.
Chat with Hiro
Get started for free today!
Accelerate Strategic R&D decision making with Synapse, PatSnap’s AI-powered Connected Innovation Intelligence Platform Built for Life Sciences Professionals.
Start your data trial now!
Synapse data is also accessible to external entities via APIs or data packages. Empower better decisions with the latest in pharmaceutical intelligence.
Bio
Bio Sequences Search & Analysis
Sign up for free
Chemical
Chemical Structures Search & Analysis
Sign up for free