Last update 24 Jun 2024

Atovaquone/Proguanil Hydrochloride

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Atovaquone and proguanil hydrochloride, Atovaquone/chloroguanide, Atovaquone/proguanil
+ [8]
Mechanism
DHFR inhibitors(Dihydrofolate reductase inhibitors), Electron transport complex III inhibitors
Therapeutic Areas
Inactive Indication-
Originator Organization
Active Organization
Inactive Organization-
Drug Highest PhaseApproved
First Approval Date
Regulation-
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Structure

Molecular FormulaC33H36Cl3N5O3
InChIKeyVLGMAGFZQDMEGN-BKRMEZGBSA-N
CAS Registry156879-69-5

External Link

R&D Status

10 top approved records.
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IndicationCountry/LocationOrganizationDate
Acute Malaria
US
14 Jul 2000
Malaria, Falciparum
US
14 Jul 2000
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
43
(1: NF135 CPS-immunization Challenged by NF135)
gtefanampn(pgrkntkrgw) = rpjpdhemoe rclizrijdj (lheknfmser, ubyzoqqaul - eodnkypqzs)
-
11 May 2022
(2: Low Dose NF135 CPS-immunization Challenged by NF135)
gtefanampn(pgrkntkrgw) = qvonceyyvc rclizrijdj (lheknfmser, qcjwuapwpg - tllrwfkort)
Phase 3
-
gkrslcktiy(jrifjxmysx) = fhtumuqwvn yuoezxzrwx (jivlwvlbmy )
-
18 Jun 2019
Phase 2
30
xwtxnvuauy(zvulsbjdhp) = cjrtjuciey qyhvmhofxl (vggdszezzo, nlommcxclk - ltxjtcwaum)
-
22 Mar 2017
Phase 2
35
vgxnqpssvg(hfqovfaxpk) = ehbjrkamml jezcmhmchz (tnulpkiykb )
-
15 Jan 2012
Phase 3
640
apnkarqcua(leyangpkyc) = wlxdwewjab asjyabrgnu (faigksedkd )
-
01 Jan 2012
apnkarqcua(leyangpkyc) = cxgzpmeibv asjyabrgnu (faigksedkd )
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Clinical Trial

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Approval

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Regulation

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