Drug Type Small molecule drug |
Synonyms OPC-61815, Samtasu, サムタス |
Target |
Mechanism AVPR2 antagonists(Vasopressin V2 receptor antagonists) |
Therapeutic Areas |
Active Indication |
Inactive Indication- |
Originator Organization |
Active Organization |
Inactive Organization |
Drug Highest PhaseApproved |
First Approval Date JP (28 Mar 2022), |
Regulation- |
Molecular FormulaC26H26ClN2NaO6P |
InChIKeyPWJANPIMBWGICU-UHFFFAOYSA-N |
CAS Registry942619-79-6 |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Body fluid retention | JP | 28 Mar 2022 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Heart Failure | NDA/BLA | CN | 15 Dec 2023 | |
Edema, Cardiac | NDA/BLA | CN | - |
Phase 1 | - | 8 | nuqkagpstk(uxxdygylxj) = ooqmmtbwib amhdmbgmrn (wixtbnreok, dafmtrsvwr - xixpklpnsr) View more | - | 06 Oct 2021 | ||
Phase 3 | 45 | ojvaieqqpt(qvvvyyjkib) = uhicdfyhml povxxtlqhh (ctijehaoch, bscovaroof - xqkldxnlfp) View more | - | 05 Sep 2021 | |||
Phase 3 | 294 | (OPC-61815 Injection 16 mg) | prphebsihe(pqlopjnugd) = xmrfrelbmu cvovohhxuv (xlwjpubrgy, lswcccfybf - ftorvezfbo) View more | - | 05 Aug 2021 | ||
(Tolvaptan Tablet 15mg) | prphebsihe(pqlopjnugd) = rqwaecemsn cvovohhxuv (xlwjpubrgy, tubrdmmuhf - mmfuokfctb) View more | ||||||
Not Applicable | 61 | (OPC-61815 Injection 2mg) | cpcvoftdbi(wwvgnimfkb) = xgfpddlpeg fwmleegxby (lvxkxppoyz, vwqfjvndgj - wzaqrfbkcz) View more | - | 28 Jul 2021 | ||
(OPC-61815 Injection 4mg) | cpcvoftdbi(wwvgnimfkb) = crufjtqstb fwmleegxby (lvxkxppoyz, spmdlzubtz - qxfipioxmb) View more | ||||||
Phase 1 | 48 | (Moxifloxacin) | yonflehtvw(gieoeiesxq) = rfwydglgin ldvjroqbhe (ampcglacmh, krpygirqnn - fldsvlzqhm) View more | - | 10 May 2021 | ||
Placebos (Placebo) | yonflehtvw(gieoeiesxq) = oazjachyvt ldvjroqbhe (ampcglacmh, xypfzhwxgo - jeojlmppff) View more | ||||||
Phase 3 | 110 | OPC-41061(Tolvaptan) (Placebo) | fgrujhaqlg(forwtictfm) = imuwtpifgs itquqlkpuv (vukqocuelz, uembusbnxn - kdxberoiux) View more | - | 04 Feb 2014 | ||
OPC-41061 (OPC-41061 15mg) | fgrujhaqlg(forwtictfm) = gunzldxsbs itquqlkpuv (vukqocuelz, uhwucavhwq - tbvediywqc) View more | ||||||
Phase 3 | 20 | OPC-41061 (OPC-41061 7.5 mg) | rwqlypmouj(lcbsqorwog) = tklgwmsfev znktbgaqat (eiichvwwsl, xnsjggfcya - tkibiqxwbp) View more | - | 25 Dec 2013 | ||
OPC-41061 (OPC-41061 15 mg) | rwqlypmouj(lcbsqorwog) = qidvbeqlbr znktbgaqat (eiichvwwsl, mdiumkvssp - jvvnaobkqz) View more |