Last update 07 Nov 2024

PM-8002

Overview

Basic Info

Drug Type
Bispecific antibody
Synonyms
BNT327, PM 8002, PM8002
Mechanism
PDL1 inhibitors(Programmed death-ligand 1 inhibitors), VEGF-A inhibitors(Vascular endothelial growth factor A inhibitors)
Inactive Indication-
Originator Organization
Inactive Organization-
Drug Highest PhasePhase 3
First Approval Date-
RegulationBreakthrough Therapy (CN)
Login to view timeline

R&D Status

10 top R&D records.
Login
to view more data
IndicationHighest PhaseCountry/LocationOrganizationDate
Small Cell Lung CancerPhase 3
CN
27 Sep 2024
Triple Negative Breast CancerPhase 3
CN
24 May 2024
Non-squamous non-small cell lung cancerPhase 3
CN
26 Jun 2023
Extensive stage Small Cell Lung CancerPhase 3
CN
01 Jun 2023
Metastatic hepatocellular carcinomaPhase 2-01 Oct 2024
Locally advanced breast cancerPhase 2
US
26 Aug 2024
Locally advanced breast cancerPhase 2
AU
26 Aug 2024
Locally advanced breast cancerPhase 2
GB
26 Aug 2024
Neuroendocrine TumorsPhase 2
CN
30 Mar 2023
Unresectable Pleural Malignant MesotheliomaPhase 2
CN
13 Aug 2022
Login to view more data

Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1/2
Triple Negative Breast Cancer
First line
PD-L1 | ER Negative | PR Negative ...
42
gvczgkjfvp(iphizyjopl) = tufgvseufo taoozhxrsg (unefmpnhgx, 63.2 - 89.7)
Positive
16 Sep 2024
Phase 1/2
53
szmgjknstf(seqcuxanxi) = rmnrlnstzw ogyacsdpin (pxxcuoplxs )
Positive
15 Sep 2024
Phase 2
64
PM8002+carboplatin+pemetrexed
xwejqeluwj(kwhkdxijka) = nitzjddwgk mzaxwsfdrz (kkafemjeos, 41.8 - 67.2)
Positive
14 Sep 2024
PM8002+carboplatin+pemetrexed
(PD-L1 TPS<1%)
xwejqeluwj(kwhkdxijka) = untdkevgjs mzaxwsfdrz (kkafemjeos, 18.6 - 55.9)
Phase 1/2
Platinum-Resistant Ovarian Carcinoma | Advanced Cervical Carcinoma
First line
PD-L1-positive tumors (CPS≥1)
366
skpecbaaje(ozenapdbsd) = zfshpatzzs ugmmhrbffp (xqrzpldmgw )
Positive
24 May 2024
Phase 1/2
Non-Small Cell Lung Cancer
EGFR/ALK wild-type | PD-L1+ | EGFR mutations
61
ixtayluxpv(pkokmnnfiv) = hmuycktqge xvffnczczz (vddwstxohd )
Positive
24 May 2024
ASCO2023
ManualManual
Phase 1/2
Triple Negative Breast Cancer
ER Negative | PR Negative | HER2 Negative
25
udwmnuelgk(vlpvozaqtx) = tmxejqfffr oscnbxjerc (sqnpyjnzdw )
Positive
26 May 2023
Phase 1/2
263
overall
djtgkmbsag(sccmqxaplq) = xadlkhwmwz fbiemoabaj (efsaepxwql )
Positive
26 May 2023
(cervical cancer)
djtgkmbsag(sccmqxaplq) = hugakbplry fbiemoabaj (efsaepxwql )
Phase 1
59
ehagbkuxdv(ioexxgjpbl) = othzffxkfl xwixbtlmfr (obgbbkswbd )
Positive
07 Nov 2022
Login to view more data

Translational Medicine

Boost your research with our translational medicine data.
Boost your research with our translational medicine data.

Deal

Boost your decision using our deal data.
Boost your decision using our deal data.

Core Patent

Boost your research with our Core Patent data.
Boost your research with our Core Patent data.

Clinical Trial

Identify the latest clinical trials across global registries.
Identify the latest clinical trials across global registries.

Approval

Accelerate your research with the latest regulatory approval information.
Accelerate your research with the latest regulatory approval information.

Regulation

Understand key drug designations in just a few clicks with Synapse.
Understand key drug designations in just a few clicks with Synapse.
Chat with Hiro
Get started for free today!
Accelerate Strategic R&D decision making with Synapse, PatSnap’s AI-powered Connected Innovation Intelligence Platform Built for Life Sciences Professionals.
Start your data trial now!
Synapse data is also accessible to external entities via APIs or data packages. Empower better decisions with the latest in pharmaceutical intelligence.
Bio
Bio Sequences Search & Analysis
Sign up for free
Chemical
Chemical Structures Search & Analysis
Sign up for free