Drug Type Small molecule drug |
Synonyms (+)- Epicatechin, Dexepicatechin, Epicatechin + [2] |
Target |
Mechanism Mitochondrial proteins inhibitors |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization Epirium Bio, Inc.Startup |
Active Organization |
Inactive Organization |
Drug Highest PhasePhase 2 |
First Approval Date- |
RegulationOrphan Drug (EU) |
Molecular FormulaC15H14O6 |
InChIKeyPFTAWBLQPZVEMU-ZFWWWQNUSA-N |
CAS Registry35323-91-2 |
Start Date13 Jul 2020 |
Sponsor / Collaborator Epirium Bio, Inc.Startup |
Start Date08 Apr 2017 |
Sponsor / Collaborator- |
Start Date01 Nov 2016 |
Sponsor / Collaborator |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
- | - | - |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Friedreich Ataxia | Phase 2 | - | - | |
Muscular Dystrophy, Duchenne | Phase 2 | - | - | |
Muscular Dystrophy, Duchenne | Phase 2 | - | - | |
Pulmonary Arterial Hypertension | Phase 1 | US | 01 Jul 2013 | |
Becker Muscular Dystrophy | Preclinical | US | Epirium Bio, Inc.Startup | 01 Nov 2016 |
Heart Failure | Preclinical | US | Epirium Bio, Inc.Startup | - |
Study | Phase | Population | Analyzed Enrollment | Group | Results | Evaluation | Publication Date |
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Phase 1/2 | 7 | htnyhpqxsh(mdtizsmptp) = lfcytetxdt mbqrufhlwu (fbffuinqzn, zwzrxlktyb - dnvpsqgbvb) View more | - | 22 Dec 2021 | |||
Phase 1/2 | 15 | (Cohort 1) | jdcdxlvvqe(ydrjrxbnpl) = ldzcvzpggi vhihrryoqi (wvmcysqqwt, lkwtcdwrdq - fkirjrvbki) View more | - | 21 Dec 2021 | ||
(Cohort 2) | jdcdxlvvqe(ydrjrxbnpl) = bfrlxbogeq vhihrryoqi (wvmcysqqwt, albjshgafd - gqckzflpfz) View more | ||||||
Phase 2 | 2 | wvqqniezet(dwcugnsydl) = rkiygxpyuj izcqyzedaa (irvpompzvj, elpvvqrvtd - cgrzjiiwkj) View more | - | 26 Jul 2021 | |||
Phase 2 | 10 | bypayjuprt(wabrwwdzfj) = koeehtreew vhngxyjidj (ksdhzdomas, nmghishnkp - fgzysnczyx) View more | - | 05 Dec 2019 | |||
Phase 1 | 12 | (10 mg (+)-Epicatechin) | elscfldifn(kadrxrqskx) = hckpusrriu nnlftwdnmz (klebqsqtft, hhrirectzp - kuctunlzmf) View more | - | 17 Apr 2017 | ||
(30 mg (+)-Epicatechin) | elscfldifn(kadrxrqskx) = aslbvodfpy nnlftwdnmz (klebqsqtft, aujunhnitf - oqahifiomk) View more |