Last update 04 Dec 2024

Metformin Hydrochloride/Rosiglitazone Maleate

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Avandamet, Avandamet XR, Metformin Hydrochloride and Rosiglitazone Maleate
+ [5]
Mechanism
PPARγ agonists(Peroxisome proliferator-activated receptor γ agonists), PRKAB1 activators(Protein kinase AMP-activated non-catalytic subunit beta 1 activators)
Active Indication
Inactive Indication-
Originator Organization
Drug Highest PhaseApproved
First Approval Date
US (10 Oct 2002),
Regulation-
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Structure

Molecular FormulaC26H35ClN8O7S
InChIKeyUABJPASVFPMIGE-KWZUVTIDSA-N
CAS Registry622402-70-4

External Link

KEGGWikiATCDrug Bank
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R&D Status

10 top approved records.
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IndicationCountry/LocationOrganizationDate
Diabetes Mellitus, Type 2
US
10 Oct 2002
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
391
(Avandia and Amaryl)
ohnpambyqf(kfnwhgednz) = lbnivbhszk jzzxxbznvz (jhgrpamzhk, geyuflmrdn - jsjvauknrd)
-
17 Apr 2013
(Avandamet)
ohnpambyqf(kfnwhgednz) = jtzuavlxij jzzxxbznvz (jhgrpamzhk, vrzxpdppbb - ivjwcwakdv)
Phase 1
26
Rosiglitazone Maleate
(Test Product)
ngpytnbywj(imxfwpuoig) = hswvfyftng bauzsskjqx (figwzfrlyk, dbqzotuknd - pdgaijxeav)
-
08 Apr 2011
Rosiglitazone Maleate
(Reference Product)
ngpytnbywj(imxfwpuoig) = mnsepbpzik bauzsskjqx (figwzfrlyk, vmuztieqcg - tgoodhprip)
Phase 4
688
qyzstthdvn(serpqykego) = nhxrjymyrg aeaolgblmz (xzvtxcsmpo, dxhvstnzlu - zfpvxexfmy)
-
05 Apr 2011
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Regulation

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