Last update 11 Oct 2025

Danicamtiv

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Danicamtiv, MYK 491, MYK-491
+ [3]
Action
stimulants
Mechanism
Cardiac myosin stimulants
Originator Organization
Inactive Organization
License Organization
Drug Highest PhasePhase 2/3
First Approval Date-
Regulation-
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Structure/Sequence

Molecular FormulaC16H20F3N5O4S
InChIKeyNREKKBAMVWQRES-MRXNPFEDSA-N
CAS Registry1970972-74-7

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Familial Dilated CardiomyopathyPhase 3-01 Nov 2025
Cardiomyopathy, DilatedPhase 2
France
06 Feb 2018
Cardiomyopathy, DilatedPhase 2
Netherlands
06 Feb 2018
Cardiomyopathy, DilatedPhase 2
Poland
06 Feb 2018
Cardiomyopathy, DilatedPhase 2
Sweden
06 Feb 2018
Heart failure with reduced ejection fractionPhase 2
United States
06 Feb 2018
Heart failure with reduced ejection fractionPhase 2
France
06 Feb 2018
Heart failure with reduced ejection fractionPhase 2
Germany
06 Feb 2018
Heart failure with reduced ejection fractionPhase 2
Netherlands
06 Feb 2018
Heart failure with reduced ejection fractionPhase 2
Poland
06 Feb 2018
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
41
(MYH7 cohort)
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Positive
29 Sep 2025
(TTN cohort)
jojtkcdgpu(bsflrsexkx) = omhfvqvydt vhwszjapge (qyymaqasqn )
Phase 2
40
xwpjaezxml(digjkwpckb) = xbkpumwhqu erwmzbzssk (rulukfkkde )
Positive
01 Sep 2020
Placebo
xwpjaezxml(digjkwpckb) = zvocufwxaj erwmzbzssk (rulukfkkde )
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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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