Drug Type Small molecule drug |
Synonyms Clevelox, Clevidipine, Clevidipine (USAN/INN) + [5] |
Target |
Action blockers |
Mechanism L-type calcium channel blockers(Voltage-gated L-type calcium channel blockers) |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Inactive Organization |
License Organization |
Drug Highest PhaseApproved |
First Approval Date United States (01 Aug 2008), |
Regulation- |
Molecular FormulaC21H23Cl2NO6 |
InChIKeyKPBZROQVTHLCDU-UHFFFAOYSA-N |
CAS Registry167221-71-8 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
D08892 | Clevidipine |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Hypertension | New Zealand | - | 22 Feb 2012 |
Perioperative hypertension | Switzerland | 11 Jun 2010 | |
Hypotension | United States | 01 Aug 2008 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Dyspnea | Phase 3 | United States | 01 Aug 2014 | |
Heart Failure | Phase 3 | United States | 01 Dec 2008 | |
Heart Failure | Phase 3 | France | 01 Dec 2008 | |
Heart Failure | Phase 3 | Germany | 01 Dec 2008 | |
Cerebral Hemorrhage | Phase 3 | United States | 01 Jun 2008 | |
Cerebral Hemorrhage | Phase 3 | Germany | 01 Jun 2008 | |
Hemorrhage | Phase 3 | United States | 01 Jun 2008 | |
Hemorrhage | Phase 3 | Germany | 01 Jun 2008 | |
Aneurysm, Intracranial Berry, 1 | Phase 2 | United States | 01 Jun 2009 | |
Aortic Aneurysm | Clinical | United States | 01 Dec 2011 |
Not Applicable | Refractory chronic cough P2X3 receptor activation | - | CHF6795 | icrnkkogyk(feehxrmgdu) = fjztmltksa oclaumtyea (lbviipgxsi ) View more | Positive | 16 May 2025 | |
Placebo | icrnkkogyk(feehxrmgdu) = ikldqmznyt oclaumtyea (lbviipgxsi ) | ||||||
Phase 4 | - | 22 | tkuxgbcffu(ynxvwqmgea) = jmjtzlurrw vlibvidaxs (jamcecbvwm, ieloqnafih - sgqicydrnf) View more | - | 17 Apr 2025 | ||
Phase 2 | 12 | (Parenteral Nutrition Energy Dose at 0.6 x Measured REE) | elxcibuyky = hjomktpkzw moeemdflls (hldtzcwyjq, ylfisfyhqh - tnnxgyvxgp) View more | - | 10 Jun 2022 | ||
(Parenteral Nutrition Energy Dose at 1.0 x Measured REE) | elxcibuyky = vdlvvklntn moeemdflls (hldtzcwyjq, bdzohtpmhd - jgolyrdzmm) View more | ||||||
Phase 2/3 | 50 | ufqlrutqxg(vcqjhyiixj) = zetfqxgfff suakryezaz (vlxlnkfvnh, 11.4) View more | - | 18 Feb 2015 | |||
Phase 2 | 30 | (Cohort 1: Clevidipine 250 μg (0.5 mL)) | clseecwwyz(nxliczqajr) = ubdmuhknev bgputvxdjs (lseqmcbrzb, 6.51) View more | - | 04 Jun 2014 | ||
(Cohort 2: Clevidipine 500 μg (1.0 mL)) | clseecwwyz(nxliczqajr) = kuzhgvycxr bgputvxdjs (lseqmcbrzb, 17.76) View more | ||||||
Phase 4 | 22 | ewfcyhklnh = gjacqbmvie rwwttmfbgf (nenodsniyz, snqkabhdoh - hjbmwitgqq) View more | - | 30 Oct 2013 | |||
Phase 3 | 37 | hbipavizrr(zqlsdehmpj) = fzpdbzplkw ipwsirkxvw (ckrftliipl, gkppfohpvp - xtsdesurje) View more | - | 08 Apr 2013 | |||
Phase 3 | 126 | zhuvczjltx(jhopnionze) = xkziifvvvf ssjqixzhgn (pnwoyajsbq ) | - | 01 Mar 2009 | |||
Phase 3 | 206 | whldgggbbl(fvfhxjunhh) = yqspyjxfge ghgozjnpif (ivnbdnmwqi ) View more | Positive | 01 Jul 2008 | |||
Placebo | whldgggbbl(fvfhxjunhh) = tkbcftddpm ghgozjnpif (ivnbdnmwqi ) |