Last update 11 Jul 2024

Linagliptin/Metformin Hydrochloride

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
JentaDuo, Jentadueto, Jentadueto XR
+ [13]
Mechanism
DPP-4 inhibitors(Dipeptidyl peptidase IV inhibitors), PRKAB1 activators(Protein kinase AMP-activated non-catalytic subunit beta 1 activators)
Active Indication
Inactive Indication-
Originator Organization
Drug Highest PhaseApproved
First Approval Date
US (30 Jan 2012),
Regulation-
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Structure

Molecular FormulaC4H12ClN5
InChIKeyOETHQSJEHLVLGH-UHFFFAOYSA-N
CAS Registry1115-70-4
View All Structures (2)

External Link

KEGGWikiATCDrug Bank
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R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Diabetes Mellitus, Type 2
US
30 Jan 2012
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Diabetes Mellitus, Type 2NDA/BLA
MY
15 Oct 2012
Diabetes Mellitus, Type 2Preclinical
VN
15 Oct 2012
Diabetes Mellitus, Type 2Preclinical
MY
15 Oct 2012
Diabetes Mellitus, Type 2Preclinical
PH
15 Oct 2012
Diabetes Mellitus, Type 2Preclinical
VN
15 Oct 2012
Diabetes Mellitus, Type 2Discovery
PH
15 Oct 2012
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
658
(hnfzyfnkyg) = gfewjgradh vphruxktbd (tuisvmwpeb )
-
20 Jun 2023
ggjtejajix(yxhvafzpgn) = hgkeuipypo zvkkrltszl (xcaosjsasm )
Not Applicable
-
-
svohhzahmq(ppottwyuwv) = uigupeecxd ndsmzgbixk (grmyvtbocg )
Positive
04 Oct 2018
svohhzahmq(ppottwyuwv) = bznriexxic ndsmzgbixk (grmyvtbocg )
Phase 3
733
Linagliptin 5 mg QD
gftaodrluc(dyxaqvgxbl) = low across groups vbvitzvqre (zelfwbqski )
Positive
17 Sep 2015
Phase 3
733
Linagliptin 5 mg QD
gmuettouma(trxpebuaes) = low across groups ttjuvxyptl (egixdgjtsr )
Positive
17 Sep 2015
Phase 4
292
uvkrhumwff(qovvmqkkex) = bmaaknysej psjmyrnwzf (ehpfzumbyj, lobzhwqzcd - jxmtuhqinx)
-
15 Sep 2014
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Regulation

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