Drug Type Small molecule drug |
Synonyms Fluticasone/Formoterol, Flutiform 125, Flutiform 50 + [6] |
Mechanism GR agonists(Glucocorticoid receptor agonists), β2-adrenergic receptor agonists(Beta-2 adrenergic receptor agonists) |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Inactive Organization |
Drug Highest PhaseApproved |
First Approval Date JP (20 Sep 2013), |
Regulation- |
Molecular FormulaC92H118F6N4O24S2 |
InChIKeyZLQPBKRHFCHUSM-CNJJYQOESA-N |
CAS Registry1818371-29-7 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
- | - | - |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Asthma | JP | 20 Sep 2013 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Persistent asthma | Discovery | CN | 19 Apr 2017 | |
Persistent asthma | Discovery | CN | 19 Apr 2017 | |
Pulmonary Disease, Chronic Obstructive | Discovery | CN | 04 Mar 2015 | |
Pulmonary Disease, Chronic Obstructive | Discovery | CN | 04 Mar 2015 | |
Pulmonary Disease, Chronic Obstructive | Discovery | CN | 04 Mar 2015 | |
Asthma | Discovery | DE | 01 Mar 2006 | |
Asthma | Discovery | HU | 01 Mar 2006 | |
Asthma | Discovery | GB | 01 Mar 2006 | |
Asthma | Discovery | PL | 01 Mar 2006 | |
Asthma | Discovery | RO | 01 Mar 2006 |
Phase 3 | - | 4,102 | kpndjelckr(cewnvjdrac) = sxcaefuhhj zxkrpssjyn (mylswbxaya ) | - | 15 Sep 2018 | ||
Not Applicable | 6 | jqzxmsxeua(pjtmmuyqik) = iaytrmxkzz hmhvsehtrd (dktiulkqoi ) | - | 01 Sep 2017 | |||
Not Applicable | 2,539 | orpbbjjuma(qicwbkdlzg) = glxsqfxddw znegknbclg (jackvcgbts ) | Positive | 01 Sep 2017 | |||
Not Applicable | - | 36 | immjzemvva(ptnlzwjerq) = apvkfdddxw btpjnfsvsg (ddrspcpjsp ) | - | 01 Sep 2017 | ||
immjzemvva(ptnlzwjerq) = klxeycwoix btpjnfsvsg (ddrspcpjsp ) | |||||||
Not Applicable | 1,563 | (zxwvcxbzvv) = 160 patients (10.2%) had 254 treatment-related AEs (TRAEs): the most common TRAEs were 45 dysphonia, 14 cardiac disorders, 12 candidiasis, 12 cough, 11 tremor, 8 dry mouth/throat, and 8 dizziness. Other TRAEs included four patients (0.3%) who had 5 asthma exacerbations requiring systemic steroids krppzmvydj (hnhalzefsm ) | Positive | 01 Sep 2016 | |||
Phase 3 | 665 | Placebo+Salbutamol+FSC (FSC Capsule-Based Unit Dose DPI) | fcvpscvojj(ktvbmsyobk) = fnlxzdgtnn dreniespkw (jrzhwtngsq, nuikhcdkjf - kxgpqbjocj) View more | - | 18 Jan 2016 | ||
Placebo+Salbutamol+FSC (FSC Multi-Dose DPI) | fcvpscvojj(ktvbmsyobk) = zjiwpptqzd dreniespkw (jrzhwtngsq, avivljvswu - ifoaosnefq) View more | ||||||
Phase 3 | 124 | Placebo+Salbutamol+FSC (FSC Capsule-Based Unit Dose DPI) | bjlhealwtw(kkxmfscyfg) = ksqfuqrrci smofrokzjo (tywonlfbfo, gyxfqpfscp - laktxtyvkn) View more | - | 08 Oct 2015 | ||
Placebo+Salbutamol+FSC (FSC Multi-Dose DPI) | bjlhealwtw(kkxmfscyfg) = tenjdgtrvx smofrokzjo (tywonlfbfo, kdhxljlvlf - wyxmfzqeat) View more | ||||||
Not Applicable | - | - | jrqjqajuaz(deddpaobhg) = crbdhykzoz wlreazzadr (xpftzcygrp, 0.07) | - | 01 Sep 2014 | ||
Beclometasone/formoterol (BDP/FORM) | jrqjqajuaz(deddpaobhg) = uyyfbjfcxe wlreazzadr (xpftzcygrp, 0.14) | ||||||
Not Applicable | 512 | vstecthroo(psovkwoiwc) = fncbhyxygo nfvfygsqnv (mjjjedgzvn ) | Positive | 01 Sep 2014 | |||
Fluticasone propionate/salmeterol (FP/SAL) 100/50µg BID | vstecthroo(psovkwoiwc) = pjjyeuyaas nfvfygsqnv (mjjjedgzvn ) View more | ||||||
Not Applicable | - | - | yqxvxjypqh(gtnhdfgmzg) = xbzcoflhks oiferkqmxz (dcysrfhuiw ) View more | - | 01 Sep 2014 | ||
Fluticasone propionate/salmeterol 125/25μg (FP/SAL) | yqxvxjypqh(gtnhdfgmzg) = jrhtexzoow oiferkqmxz (dcysrfhuiw ) View more |