Delving into the Latest Updates on Fisons Ltd. with Synapse

Overview

本研究的总体目的是在中度至极重度COPD受试者中，使用格隆铵和富马酸福莫特罗MDI（GFF MDI，14.4/9.6 μg 释出剂量， BID）、富马酸福莫特罗MDI（FF MDI，9.6μg 释出剂量， BID）和格隆铵MDI（ GP MDI，14.4 μg释出剂量， BID）相互比较以及与安慰剂MDI相比，治疗24周的疗效和安全性。

[Translation]

The overall objective of this study was to compare the efficacy and safety of glycopyrronium and formoterol fumarate MDI (GFF MDI, 14.4/9.6 μg delivered dose, BID), formoterol fumarate MDI (FF MDI, 9.6 μg delivered dose, BID), and glycopyrronium MDI (GP MDI, 14.4 μg delivered dose, BID) with each other and compared with placebo MDI in subjects with moderate to very severe COPD for 24 weeks.

Start Date26 Apr 2016

Sponsor / Collaborator

AstraZeneca Investment (China) Co. Ltd.

[+2]

100 Clinical Results associated with Fisons Ltd.

Login to view more data

0 Patents (Medical) associated with Fisons Ltd.

Login to view more data

449

Literatures (Medical) associated with Fisons Ltd.

11 May 2011·Journal of Pharmacy and Pharmacology

The fate of [14C] lactose administered into the lungs of rats and monkeys

Article

Author: Moss, G F ; Ritchie, Jean T ; Clark, B

After intratracheal administration of 20 mg Intal (a 1:1 disodium cromoglycate-lactose mixture) [15826-37-6] to monkeys, the lactose [63-42-3] was absorbed unchanged by the lungs and excreted in urine.Little metabolism of lactose by rat lung was observed in vivo or in vitro.Lactose is used to improve the flow properties of the aerosol powder of disodium cromoglycate administered in the treatment of asthma.

12 Apr 2011·Journal of Pharmacy and PharmacologyQ3 · MEDICINE

Isolation and identification of the fluorescent degradation product of some β-lactam antibiotics

Q3 · MEDICINE

Article

Author: Barbhaiya, R H ; Payling, D W ; Turner, P ; Brown, R C

AbstractA fluorescent degradation product of cephalexin, recently employed in the determination of this antibiotic in aqueous solution and human plasma, has been isolated and identified as 2-hydroxy-3-phenyl-6-methylpyrazine. Spectroscopically and chromatographically the product is indistinguishable from that obtained by the same method from a series of other cephalosporins and penicillins bearing an α-amino group on the side-chain, and from the pyrazine structure produced by synthesis. Two reported methods for the fluorimetric determination of ampicillin have also been found to yield the same degradation product and not the suggested diketopiperazine structure.

12 Apr 2011·Journal of Pharmacy and PharmacologyQ3 · MEDICINE

A simple colorimetric method for the estimation of d(−)-penicillamine in plasma

Q3 · MEDICINE

Article

Author: Mann, J ; Mitchell, P D

A simple colorimetric method based on the reaction of 5,5'-dithiobis-2-(nitrobenzoic acid) with D-(-)-penicillamine (I) [52-67-5] was used to measure the plasma concentration of I in rabbits after administration of the drug by various routes.A calibration curve for I in a pooled sample of rabbit plasma was linear to 50 μg I/mL and concentrations down to 2 μg/mL could be detected.The method gave a recovery of 66% of I added to plasma.Plasma from 5 rheumatoid arthritis patients receiving chronic I (125 mg) therapy was also analyzed; 2 h after I therapy plasma I concentration was <2 μg/mL.

100 Deals associated with Fisons Ltd.

Login to view more data

100 Translational Medicine associated with Fisons Ltd.

Login to view more data

Corporation Tree

Boost your research with our corporation tree data.

login

or

view full example data

Boost your research with our corporation tree data.

Pipeline

Pipeline Snapshot as of 22 Nov 2024

The statistics for drugs in the Pipeline is the current organization and its subsidiaries are counted as organizations,Early Phase 1 is incorporated into Phase 1, Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3

Other

4

Login to view more data

Current Projects

Drug(Targets)	Indications	Global Highest Phase

FPL-62064 ( 5-LOX x COX )	Colitis, Ulcerative More	Discontinued
Fluticasone Propionate/Formoterol Fumarate Hydrate ( GR x β2-adrenergic receptor )	Pulmonary Disease, Chronic Obstructive More	Pending
FPL-67121 ( Adenosine receptor )	Thromboembolism More	Pending
Formoterol Fumarate/Glycopyrrolate ( mAChRs x β2-adrenergic receptor )	Pulmonary Disease, Chronic Obstructive More	Pending