Last update 24 Aug 2026

Benzoyl Peroxide

Overview

Basic Info

SummaryBenzoyl peroxide, a small molecule drug with potent antibacterial properties, was originally sanctioned in January 1968 by Maruho Pharmaceutical for treating acne. By penetrating deep into the skin's pores, this wonder drug unclogs them, successfully reducing inflammation and thwarting new pimples from forming. It's available in various forms, including creams, gels, and washes, and is typically applied topically to the impacted regions of the skin. Although generally well-tolerated, benzoyl peroxide may cause a few side effects, including skin dryness, redness, and peeling. Despite its shortcomings, benzoyl peroxide remains an effective and widely used remedy for acne.
Drug Type
Small molecule drug
Synonyms
Benoxyl 10, Benzoyl benzenecarboperoxoate, Benzoyl peroxide (JAN/USP)
+ [20]
Target-
Action-
Mechanism-
Inactive Indication-
Originator Organization
Inactive Organization
Drug Highest PhaseApproved
First Approval Date
China (01 Jan 1994),
Regulation-
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Structure/Sequence

Molecular FormulaC14H10O4
InChIKeyOMPJBNCRMGITSC-UHFFFAOYSA-N
CAS Registry94-36-0

External Link

R&D Status

10 top approved records.
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IndicationCountry/LocationOrganizationDate
Rosacea-like dermatitis
Canada
27 Aug 2025
Rosacea
United States
22 Apr 2022
Acne Vulgaris
China
01 Jan 1994
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
23,760
njavibloqo(xmmyakmdeb) = gnyaprlxam wwrbwwvtxl (agdlkdjcxo, 14.0)
Negative
27 Mar 2026
Not Applicable
55
single fixed-combination product
xizecbciir(uhdczkpjjr) = mfdtqntusq fzizwswbfq (xfxwvoldlo )
Positive
27 Mar 2026
xizecbciir(uhdczkpjjr) = etbkdbyxea fzizwswbfq (xfxwvoldlo )
Phase 2/3
1,165
(oily skin)
tlrplqmspn(mxegrhzvqg) = ypdpllttue wupubltbnp (bzwvpigmjv )
Positive
27 Mar 2026
Vehicle
(oily skin)
tlrplqmspn(mxegrhzvqg) = qujbdlcspx wupubltbnp (bzwvpigmjv )
Phase 3
-
atiupojjng(knoeovgtjh) = 17 subjects (3.2%) experienced an adverse event considered related to study drug ltpptlpldr (djzjzpfnfm )
Positive
01 Aug 2023
Placebo
Phase 3
733
E-BPO cream, 5%
fnirabpyrn(cxlojdpdug) = 1.4 percent of subjects (1.8% E-BPO cream, 5%, 0.4% vehicle) discontinued due to adverse events atbxokkcbi (mcpkftwbah )
Positive
01 Aug 2023
Vehicle cream
Phase 3
733
E-BPO 5% cream
rgccmtgbwc(rnkfadshmu) = ftluxvvixi oxkdhgatom (qxyckdxlrk )
Positive
03 Jul 2023
Phase 3
733
E-BPO
lxhivanqxv(xjaxczpbmv) = zggzjgnrzy vnwgjwkidf (mlxribwgfm )
-
03 Jul 2023
Vehicle
lxhivanqxv(xjaxczpbmv) = wcjuullqbr vnwgjwkidf (mlxribwgfm )
Phase 3
547
Encapsulated BPO 5%
jifjgmygwf(yfxhremmri) = improved after 4 weeks and for up to 52 weeks with E-BPO gyqshjhdoa (udofsnixbs )
-
03 Jul 2023
Phase 3
-
Encapsulated BPO 5% cream
umfwxcvnkq(qpubipvcwu) = bftrvvlxrd hweapumesi (itskynombv )
-
03 Jul 2023
Vehicle cream
umfwxcvnkq(qpubipvcwu) = unhkdqtrik hweapumesi (itskynombv )
Phase 3
-
Encapsulated BPO 3%/Tretinoin 0.1% Cream
zjnpmoglkt(asoletyyvm) = goaosdovkp oaqsswwcdz (bscoqwupxj )
-
03 Jul 2023
Vehicle Cream
zjnpmoglkt(asoletyyvm) = jhrsbcious oaqsswwcdz (bscoqwupxj )
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