Last update 31 May 2025

Rimonabant

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
rimonabant, Rimonabant (JAN/USAN/INN), Zimulti
+ [7]
Target
Action
antagonists
Mechanism
CB1 antagonists(Cannabinoid CB1 receptor antagonists)
Active Indication-
Originator Organization
Active Organization-
License Organization-
Drug Highest PhaseWithdrawn
First Approval Date
European Union (19 Jun 2006),
Regulation-
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Structure/Sequence

Molecular FormulaC22H21Cl3N4O
InChIKeyJZCPYUJPEARBJL-UHFFFAOYSA-N
CAS Registry168273-06-1

External Link

KEGGWikiATCDrug Bank
D05731Rimonabant

R&D Status

Approved
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IndicationCountry/LocationOrganizationDate
Obesity
European Union
19 Jun 2006
Obesity
Iceland
19 Jun 2006
Obesity
Liechtenstein
19 Jun 2006
Obesity
Norway
19 Jun 2006
Overweight
European Union
19 Jun 2006
Overweight
Iceland
19 Jun 2006
Overweight
Liechtenstein
19 Jun 2006
Overweight
Norway
19 Jun 2006
Developing
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IndicationHighest PhaseCountry/LocationOrganizationDate
Nonalcoholic SteatohepatitisPhase 3
United States
01 Jan 2008
Nonalcoholic SteatohepatitisPhase 3
China
01 Jan 2008
Nonalcoholic SteatohepatitisPhase 3
Argentina
01 Jan 2008
Nonalcoholic SteatohepatitisPhase 3
Australia
01 Jan 2008
Nonalcoholic SteatohepatitisPhase 3
Belgium
01 Jan 2008
Nonalcoholic SteatohepatitisPhase 3
Brazil
01 Jan 2008
Nonalcoholic SteatohepatitisPhase 3
Chile
01 Jan 2008
Nonalcoholic SteatohepatitisPhase 3
Colombia
01 Jan 2008
Nonalcoholic SteatohepatitisPhase 3
Croatia
01 Jan 2008
Nonalcoholic SteatohepatitisPhase 3
France
01 Jan 2008
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
66
(Rimonabant)
lsqambjbgm(fiqjkbdwoj) = vcxbttvaff wejvuqmksk (iubzelptdy, 5.59)
-
15 May 2017
placebo
(Placebo)
lsqambjbgm(fiqjkbdwoj) = hvxhewsltt wejvuqmksk (iubzelptdy, 7.87)
Phase 3
-
18,695
eskmwpuqry(ajlmqpumyv) = 3038 [33%] vs 2084 [22%] dmkzvtyapn (ddkfqenfcg )
-
14 Aug 2010
Placebo
Phase 3
755
Rimonabant + Nicotine patch
esomnvgzto(azjmmwdsbs) = linrfyawgb ulrohrbxue (yfrdxnwfto )
Positive
01 Feb 2009
esomnvgzto(azjmmwdsbs) = shinbeemqc ulrohrbxue (yfrdxnwfto )
Phase 3
839
dimsxkpowk(xvavtjydkg) = fuibgkkttc pnilynhwjt (kbexohanet, -0.04% - 0.54%)
-
02 Apr 2008
Placebo
dimsxkpowk(xvavtjydkg) = uezomjimfv pnilynhwjt (kbexohanet, 0.22% - 0.80%)
Phase 3
1,036
Placebo
behdhjhsxi(zwmtfztjst) = ajfisrgkwi sskitjlcbj (dldmlzopor )
-
17 Nov 2005
behdhjhsxi(zwmtfztjst) = fipyoasldw sskitjlcbj (dldmlzopor )
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Regulation

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