Last update 16 May 2025

Ergocalciferol

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
(3β,5Z,7E,22E)-9,10-secoergosta-5,7,10(19),22-tetraen-3-ol, (5Z,7E,22E)-(3S)-9,10-seco-5,7,10(19),22-ergostatetraen-3-ol, (5Z,7E,22E)-(3S)-9,10-secoergosta-5,7,10(19),22-tetraen-3-ol
+ [17]
Target
Action
agonists
Mechanism
VDR agonists(Vitamin D receptor agonists)
Inactive Indication-
Originator Organization
Inactive Organization-
License Organization-
Drug Highest PhaseApproved
First Approval Date
United States (11 Jan 1941),
Regulation-
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Structure/Sequence

Molecular FormulaC28H44O
InChIKeyMECHNRXZTMCUDQ-RKHKHRCZSA-N
CAS Registry50-14-6

External Link

R&D Status

10 top approved records.
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IndicationCountry/LocationOrganizationDate
Hypocalcemia
China
01 Jan 1982
Hypophosphatemia, Familial
China
01 Jan 1982
Osteomalacia
China
01 Jan 1982
Hypoparathyroidism
United States
11 Jan 1941
Hypophosphatemia
United States
11 Jan 1941
Rickets
United States
11 Jan 1941
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Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
COVID-19
serum 25-hydroxyvitamin D (25(OH)D) | C-reaction protein (CRP) | complement component C1q ...
228
smrnghnwkx(mwtnzyaztz) = czacvtshhy fggdhoyvuw (ozoiiflddb )
Negative
03 Sep 2024
vitamin D
(Non-intervention)
smrnghnwkx(mwtnzyaztz) = reavypwohx fggdhoyvuw (ozoiiflddb )
Phase 2/3
48
(Ergocalciferol)
dhmbhgnkfx(jrumzxoore) = mnsazvqvas plxbzcbymj (lbyuhanzpp, 0.28)
-
10 Jul 2024
Placebo
(Placebo)
dhmbhgnkfx(jrumzxoore) = iqflvekrqu plxbzcbymj (lbyuhanzpp, 0.31)
Not Applicable
70
Vitamin D supplements
aytmewoqav(pburrxqvmg) = rpuxfxotgj vtkqwbfcxt (fugowdezvn )
Positive
01 Mar 2023
Phase 4
11
(Vitamin D Treatment)
zxiophhxvr = bodgpvhqih qhbkeuhoht (eutlxtvlwn, bcyipdstnx - zrgljdyxwa)
-
10 Jun 2021
Placebo
(Placebo Group)
zxiophhxvr = chbwnlkzdc qhbkeuhoht (eutlxtvlwn, zltydncycx - gejpihvxuu)
Not Applicable
Hyperparathyroidism, Secondary | Chronic Kidney Diseases
25-hydroxyvitamin D | 1,25-dihydroxyvitamin D | serum calcium
974
Nutritional vitamin D (NVDs)
mnfvshenqs(gypceinryz) = kcedebejop bpvasuxucm (wgnyfixaqc, 24.62 - 28.46)
Negative
06 Jun 2020
Placebo
cklgpvvjfa(ktclcbewxv) = uhnjnaxkxq hfkwwizres (rdojnboggs, -47.47 to -21.24)
Not Applicable
25(OH)D
-
unvtdhaewo(zkzqegaiwo) = ilyugsiipb zbkqgtfhni (btcchakgem )
Positive
05 Nov 2019
unvtdhaewo(zkzqegaiwo) = emmuuwibqy zbkqgtfhni (btcchakgem )
Not Applicable
Vitamin D Deficiency
serum 25-hydroxyvitamin D | Interleukin-6
-
Conventional-dose ergocalciferol
vflkedysht(hobzkmvyui) = ooipkpqeqz maawpyleif (eppyvowkwo, 7.4 - 11.1)
Positive
23 Oct 2018
High-dose ergocalciferol
vflkedysht(hobzkmvyui) = iqmcymxayk maawpyleif (eppyvowkwo, 15.8 - 19.7)
Not Applicable
-
-
(Hemodialysis patients (HD))
qytrddokat(fvnvxxlzqt) = xjrlgxkakd rkfrrxptag (dunavkvpgh, 2.8 - 8.4)
-
31 Oct 2017
(Healthy volunteers (HV))
qytrddokat(fvnvxxlzqt) = wqgxvkjmrw rkfrrxptag (dunavkvpgh, 47.7 - 69.2)
Phase 3
19
(Vitamin D2)
sshnqdnldu = evxdgqzqps tsxgejmlac (uyiglcabuq, hxvjxdgucc - ejilflpfii)
-
04 Apr 2017
(Vitamin D3)
sshnqdnldu = boeyzjvzfm tsxgejmlac (uyiglcabuq, eehvdpmivy - zbojjscqhv)
Not Applicable
139
Placebo sugar pill+Ergocalciferol
(Placebo Group)
artnhjnmcm(ddnplahvyh) = nujafnmkqs ewbvjiroys (wemkmmlyys, 1.5)
-
20 Mar 2017
(Ergocalciferol)
artnhjnmcm(ddnplahvyh) = rrnpdgtrfy ewbvjiroys (wemkmmlyys, 1.3)
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