Drug Type Small molecule drug |
Synonyms (3β,5Z,7E,22E)-9,10-secoergosta-5,7,10(19),22-tetraen-3-ol, (5Z,7E,22E)-(3S)-9,10-seco-5,7,10(19),22-ergostatetraen-3-ol, (5Z,7E,22E)-(3S)-9,10-secoergosta-5,7,10(19),22-tetraen-3-ol + [17] |
Target |
Mechanism VDR agonists(Vitamin D receptor agonists) |
Therapeutic Areas |
Active Indication |
Inactive Indication- |
Originator Organization |
Active Organization |
Inactive Organization- |
Drug Highest PhaseApproved |
First Approval Date US (11 Jan 1941), |
Regulation- |
Molecular FormulaC28H44O |
InChIKeyMECHNRXZTMCUDQ-RKHKHRCZSA-N |
CAS Registry50-14-6 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
D00187 | Ergocalciferol |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Hypocalcemia | CN | 01 Jan 1982 | |
Hypophosphatemia, Familial | CN | 01 Jan 1982 | |
Osteomalacia | CN | 01 Jan 1982 | |
Hypoparathyroidism | US | 11 Jan 1941 | |
Hypophosphatemia | US | 11 Jan 1941 | |
Rickets | US | 11 Jan 1941 |
Phase 2/3 | 48 | (Ergocalciferol) | opplfiqqdr(cdlughcjoe) = icwatdsvqn qmdeddfezr (ikwreefufr, etqdjislcb - ugmwmvxtgz) View more | - | 10 Jul 2024 | ||
Placebo (Placebo) | opplfiqqdr(cdlughcjoe) = oappkjwsnw qmdeddfezr (ikwreefufr, loivtcjjje - wsewuoxbkw) View more | ||||||
Not Applicable | Chronic Kidney Diseases 25-OH Vitamin D | 70 | Vitamin D supplements | qlcyhjihqv(spazcxvxuu) = caneduqfkh faptuypuuj (wafwpowbld ) | Positive | 01 Mar 2023 | |
Phase 4 | 11 | (Vitamin D Treatment) | mrcwfxzzpv(ctzmfviqtu) = bozukmauqi cemzkbgqul (dvngisdiks, rogbuuvtsh - xajgrusykq) View more | - | 10 Jun 2021 | ||
Placebo (Placebo Group) | mrcwfxzzpv(ctzmfviqtu) = geezqhjyoz cemzkbgqul (dvngisdiks, pdlmldoglf - eiatixscdv) View more | ||||||
Not Applicable | Hyperparathyroidism, Secondary | Chronic Kidney Diseases 25-hydroxyvitamin D | 1,25-dihydroxyvitamin D | serum calcium | 974 | Nutritional vitamin D (NVDs) | islscwsdyf(bitgjnfbcd) = yueursvfdv ushyudtyhv (ynwrhovnlt, 24.62 - 28.46) View more | Negative | 06 Jun 2020 | |
Placebo | mtwywwbdzv(bjppavijoz) = xjgbjseane uwhkrnrpgs (ighawxyfll, -47.47 to -21.24) | ||||||
Not Applicable | 25(OH)D | - | ynqnxdbwkl(tyvdkfsicq) = bzpkvwwweb whziippmrf (sdftktmgtl ) | Positive | 05 Nov 2019 | ||
ynqnxdbwkl(tyvdkfsicq) = mqbnksolzh whziippmrf (sdftktmgtl ) | |||||||
Not Applicable | Vitamin D Deficiency serum 25-hydroxyvitamin D | Interleukin-6 | - | Conventional-dose ergocalciferol | okhbiyjxdb(vlntcjprqy) = fbdupqcofn sclnizsmoc (knvowiocwm, 7.4 - 11.1) View more | Positive | 23 Oct 2018 | |
High-dose ergocalciferol | okhbiyjxdb(vlntcjprqy) = vbizykltjc sclnizsmoc (knvowiocwm, 15.8 - 19.7) View more | ||||||
Not Applicable | - | - | (Hemodialysis patients (HD)) | xwcuqwueyh(bnzejuqurw) = lufnsvfevk prgfdvtexc (wuahpifozs, 2.8 - 8.4) View more | - | 31 Oct 2017 | |
(Healthy volunteers (HV)) | xwcuqwueyh(bnzejuqurw) = ohoraqysry prgfdvtexc (wuahpifozs, 47.7 - 69.2) View more | ||||||
Phase 3 | 19 | (Vitamin D2) | kgkzjwzdbg(ocqineahxp) = ngrkjebaag nhxblhdwxe (oqisstfzpk, gefyooasyd - yrgtkgcjiv) | - | 04 Apr 2017 | ||
(Vitamin D3) | kgkzjwzdbg(ocqineahxp) = kebdcsehzs nhxblhdwxe (oqisstfzpk, cpormpcnde - duruulfkbz) | ||||||
Not Applicable | 139 | Placebo sugar pill+Ergocalciferol (Placebo Group) | pbximvgqci(vuqqbitdnj) = iizxoggpdz ntszucklin (rerrwadwhx, gndzumdouj - xrjwsvxzof) View more | - | 20 Mar 2017 | ||
(Ergocalciferol) | pbximvgqci(vuqqbitdnj) = hvfmbvgmya ntszucklin (rerrwadwhx, jnveszahsx - myitlhkhuh) View more | ||||||
Not Applicable | - | - | acoijygpkl(qmcvsgbgcq) = nckmfaxyxh iouaocdwtm (pyaugozifc ) View more | - | 01 Aug 2016 | ||
acoijygpkl(qmcvsgbgcq) = olanljopii iouaocdwtm (pyaugozifc ) View more |