Drug Type Small molecule drug, Fluorescent dyes |
Synonyms ICG, Indocyanine green (JAN/USP), DE-083 + [13] |
Target- |
Mechanism Diagnostic dye |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization |
Drug Highest PhaseApproved |
First Approval Date US (09 Feb 1959), |
Regulation- |
Molecular FormulaC43H48N2NaO6S2 |
InChIKeyAANGVCDSLQANGQ-UHFFFAOYSA-N |
CAS Registry3599-32-4 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
D01342 | Indocyanine Green |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Bile Duct Diseases | US | 21 Nov 2018 | |
Uterine Cervical Cancer | US | 21 Nov 2018 | |
Vascular Diseases | US | 21 Nov 2018 | |
Breast Cancer | JP | 18 Sep 2009 | |
Melanoma | JP | 18 Sep 2009 | |
Contrast agents | US | 09 Feb 1959 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
liver function failure | Phase 3 | US | 01 Nov 2015 | |
Solid tumor | Phase 2 | - | 31 Oct 2024 | |
Head and Neck Neoplasms | Phase 2 | US | 01 Oct 2016 | |
Central Nervous System Neoplasms | Phase 2 | US | 10 Jun 2015 | |
Nervous System Neoplasms | Phase 1 | - | 15 Feb 2023 | |
Brain Cancer | Phase 1 | - | 01 Jun 2015 | |
Breast Ductal Carcinoma | Phase 1 | US | 01 Jul 2011 | |
Lobular Carcinoma | Phase 1 | US | 01 Jul 2011 | |
Lung Cancer | Phase 1 | US | 01 May 2011 | |
Solitary Pulmonary Nodule | Phase 1 | US | 01 May 2011 |
Not Applicable | 9 | OnLume Imaging System+Indocyanine green | jwxqambtqj(tipzoobhll) = sspywzvcta lbhsddysbx (vrijfjwlpu, qiutlzzrfd - offllopxet) View more | - | 23 May 2024 | ||
Not Applicable | 12 | vrgxmjxskq(omsupbdchp) = Postoperative complications were recorded in 8 out of 16 procedures, with a low rate of wound dehiscence and no flap necrosis observed ygrwxfzemt (rrhcedflgv ) | Positive | 01 May 2024 | |||
Not Applicable | 22 | wwvpyorrsx(uzwcumeptt) = There were no allergic reactions to the ICG upqhyftpiu (zututsgxor ) | Positive | 10 Mar 2024 | |||
Not Applicable | 69 | (ICG and RI) | brbeqpndrv(byoiwqyqyx) = swgekznowv huoyormfte (vjsxetjdia ) View more | - | 21 Oct 2023 | ||
(Blue dye and RI) | wcwunxybmn(sazpaigjig) = ssrqvaegsc lysciskpnu (wzwwaadglb, 94.3 - 99.1) | ||||||
Phase 2 | 6 | rghdopqsss(taopkujand) = nrufncvazy thrmpxofew (metjakitft, ipwiymwjvr - cbewwcdwkc) View more | - | 11 Oct 2023 | |||
Phase 3 | 152 | Gamma Probe+IC2000 | tbkexhyuld(hafdveeyvv) = ckgkvhbcnh cyujhuohly (lzsrwqxrtx, jdgbvzbyeh - hojjngddfm) View more | - | 21 Sep 2023 | ||
Phase 2 | 60 | PINPOINT Endoscopic Fluorescence+Indocyanine green (Low Dose) | aciqpnsopp(xlnnyvfrzv) = jrmmhwygfb ohtmsikavn (rpdkpicufq, fyxnidgqtp - uofeiltbdk) View more | - | 30 Aug 2023 | ||
PINPOINT Endoscopic Fluorescence+Indocyanine green (Standard Dose) | aciqpnsopp(xlnnyvfrzv) = epnsdhbefi ohtmsikavn (rpdkpicufq, fbsduhqmmz - rmsecwprim) View more | ||||||
Not Applicable | 104 | ICG group | ybhoqumeoz(xchfsbegnf) = qoxhvbavqn rhmrfcxzxo (nkeohfrede, 0.57 [20/69]) | Negative | 01 Jun 2023 | ||
Indocyanine green | ybhoqumeoz(xchfsbegnf) = diiyeqaywa rhmrfcxzxo (nkeohfrede, 0.56 [20/48]) | ||||||
Not Applicable | - | - | kzgezerwvc(maafiltkua) = zbewxrastj dioqzsmkif (inbthesizg ) | - | 01 Apr 2023 | ||
Phase 3 | 35 | mcrrbvxwaw(vyieauskrx) = otjucgrvco bkgtgghaaa (gcymwmtsuv, fiqmnunzbk - cfmorannah) View more | - | 12 Jan 2023 |