Last update 05 Nov 2024

Indocyanine Green

Overview

Basic Info

Drug Type
Small molecule drug, Fluorescent dyes
Synonyms
ICG, indocyanine green (ICG), Indocyanine green (JAN/USP)
+ [14]
Target
Mechanism
STT3B inhibitors(STT3 oligosaccharyltransferase complex catalytic subunit B inhibitors), Diagnostic dye
Originator Organization
Drug Highest PhaseApproved
First Approval Date
US (09 Feb 1959),
Regulation-
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Structure

Molecular FormulaC43H48N2NaO6S2
InChIKeyAANGVCDSLQANGQ-UHFFFAOYSA-N
CAS Registry3599-32-4

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Bile Duct Diseases
US
21 Nov 2018
Uterine Cervical Cancer
US
21 Nov 2018
Vascular Diseases
US
21 Nov 2018
Breast Cancer
JP
18 Sep 2009
Melanoma
JP
18 Sep 2009
Contrast agents
US
09 Feb 1959
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
liver function failurePhase 3
US
01 Nov 2015
Solid tumorPhase 2
US
14 Aug 2024
Head and Neck NeoplasmsPhase 2
US
01 Oct 2016
Central Nervous System NeoplasmsPhase 2
US
10 Jun 2015
Brain CancerPhase 1-01 Jun 2015
Breast Ductal CarcinomaPhase 1
US
01 Jul 2011
Lobular CarcinomaPhase 1
US
01 Jul 2011
Lung CancerPhase 1
US
01 May 2011
Solitary Pulmonary NodulePhase 1
US
01 May 2011
Choroidal NeovascularizationPreclinical
US
01 Jun 2021
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
-
ICG inhalation for 5 minutes
fndiwhfoan(wusemnplyi) = No other complications were observed scibwuotld (qqhoofhyfh )
-
09 Sep 2024
ICG inhalation for 10 minutes
Not Applicable
-
-
Indocyanine Green (ICG) Inhalation
vyjfebegvc(pqzsztqtnw) = None of the patients experienced complications related to ICG inhalation dcynixnrol (lmocxsutjs )
-
07 Sep 2024
Not Applicable
-
(Mesh nebulizer)
mrwiyfvpjm(aejelkgtjr) = no adverse events were recorded gxsdfdkxoe (ofrpfrfujx )
-
07 Sep 2024
Not Applicable
3
fluorescent Peptide+indocyanine green
dvxyskrrga(zlmqnkzaxj) = gyibkqsoab tnxyctldum (prmygjfmeh, ltmfxcbakw - lwusypvvut)
-
26 Jun 2024
Not Applicable
9
OnLume Imaging System+Indocyanine green
vogtydwkri(nurzisgbhs) = szeeraccro bubknuftnm (ajnmhhzrvb, uygonhfjxp - omxwprrwvz)
-
23 May 2024
Not Applicable
12
stxrrnvzdj(dxwsemtkgc) = Postoperative complications were recorded in 8 out of 16 procedures, with a low rate of wound dehiscence and no flap necrosis observed liwkelywcp (imcsribhsg )
Positive
01 May 2024
Not Applicable
22
bsvimikwel(gjebteokbm) = There were no allergic reactions to the ICG scsgllivmi (zzqjnkvxjg )
Positive
10 Mar 2024
Not Applicable
69
(ICG and RI)
xzmznjvsck(epdiyjqnjr) = gbvtijmlzy kifcukzxee (krnralpmhb )
-
21 Oct 2023
(Blue dye and RI)
dulekkbhvh(zybjaeafgv) = xnqywiigjz kjurzrasrj (uwianwliuu, 94.3 - 99.1)
Phase 2
6
Single Photon Emission Computed Tomography (SPECT)+Lymphoseek+Indocyanine Green (ICG)
myhmkqqdig(asyeavjysh) = adxplkmdlj tbbazxfkyr (nifbhmrgyy, norgisliju - ssmsbgjmhm)
-
11 Oct 2023
Phase 1
12
psxflrxryd(qrlikgvydv) = ICG guidance failed to localize pulmonary metastases in five (42%) patients who had inflammatory myofibroblastic tumor, atypical cartilaginous tumor, neuroblastoma, adrenocortical carcinoma, or papillary thyroid carcinoma idssxfylnx (tfuvglfgvg )
Negative
01 Oct 2023
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Regulation

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