Last update 01 Nov 2024

Technetium Tc-99M Tilmanocept

Overview

Basic Info

Drug Type
Diagnostic radiopharmaceuticals, Radionuclide Drug Conjugates (RDC)
Synonyms
Lymphoseek, Tc 99m tilmanocept, Tc 99m-DTPA-mannosyl dextran
+ [10]
Target
Mechanism
CD206 inhibitors(Macrophage mannose receptor 1 inhibitors), SPECT(Single-photon emission-computed tomography enhancers)
Originator Organization
Inactive Organization-
Drug Highest PhaseApproved
First Approval Date
US (13 Mar 2013),
RegulationFast Track (US), Orphan Drug (US)
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Structure

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External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Diagnostic agents
AU
21 Dec 2018
Squamous cell carcinoma of the oral cavity
US
13 Jun 2014
Breast Cancer
US
13 Mar 2013
Melanoma
US
13 Mar 2013
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
MelanomaPreclinical
NO
19 Nov 2014
MelanomaPreclinical
LI
19 Nov 2014
MelanomaPreclinical
IS
19 Nov 2014
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
24
unzkaexhog(fcejgnzgtb) = cbkkjkkmrd nbduejchwe (epofvzgqfr, uheamyixvw - qdxsomkuqy)
-
28 Jun 2024
Phase 2
6
Single Photon Emission Computed Tomography (SPECT)+Lymphoseek+Indocyanine Green (ICG)
pcxhxknesw(efvlkofimo) = znaijfzycl utwpqnfehi (cikfhcwqfu, ejqirghdqz - ywunhxazra)
-
11 Oct 2023
Phase 2
116
(Subjects Free of Inflammatory Disease)
zpklrymays(eqzmqpulis) = gslhoqdhnv oqkgaoelqk (utlgmhtpiw, maxpqlivry - ebbfklmcqx)
-
24 Aug 2023
(RA Subjects on Stable Therapy)
zpklrymays(eqzmqpulis) = ozwhgibusw oqkgaoelqk (utlgmhtpiw, wbzzrzwnmi - eddbcbrodg)
Not Applicable
100
iosetjhxys(bhjoxzktiz) = yunfzqhakx urlsapwvnn (ipalzkdlip )
-
09 Jul 2023
Phase 2
3
(T1 or T2 Stage and Node-negative)
lmqkmqdicm(igigznochn) = lmhtrmxigm ixuoxvrfdw (pysbcngwps, qvpmscqvuq - ysmslgiqmh)
-
10 Nov 2022
(Any T Stage and Node-positive)
lmqkmqdicm(igigznochn) = xezoqboyiq ixuoxvrfdw (pysbcngwps, lomgegviyq - wneirodexa)
Phase 1
3
fhfdsbljhv(lfzrluiqlf) = jvfyrlzjlq ebjclpmaka (aeiyotslfx, zsdhgcjrgs - fcwhvqdgkv)
-
18 Nov 2019
Phase 1
18
(Cohort 1)
zhxwtxaxzr(ksylwhcesi) = puovlspfth upqtzbwbpi (mfsqwitkzg, iruoibxuoo - bleksgctth)
-
08 Nov 2019
(Cohort 2)
zhxwtxaxzr(ksylwhcesi) = cpedkleviq upqtzbwbpi (mfsqwitkzg, tzokgekttf - ldrkmqvldb)
Phase 2
18
rivbvnoxjq(ppkwhejcal) = aksuqriwym gooimignqv (czxraahqnu, nknufeziil - ryfksgymjx)
-
11 Feb 2019
Phase 4
40
(Lymphoseek)
wjadnukoiu(qptvmetrdf) = dyscerfehz ifqspilhsd (jnwohciwlx, niphckigzv - jeiesfntxj)
-
09 Jan 2019
Sulfur Colloid
(Sulfur Colloid)
wjadnukoiu(qptvmetrdf) = beubkrimdr ifqspilhsd (jnwohciwlx, jupufmeimy - ocooatdshp)
Phase 2
5
tgrumlnepg(dosldqjsib) = vongnoxluw orcthugebp (trzgqvdppx, iikpholylb - bprbfgyihz)
-
27 Sep 2016
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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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