Last update 01 Nov 2024

Pracinostat Hydrochloride

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Pracinostat
Mechanism
HDAC1 inhibitors(Histone deacetylase 1 inhibitors), HDAC2 inhibitors(Histone deacetylase 2 inhibitors)
Active Indication-
Originator Organization
Active Organization-
Drug Highest PhaseDiscontinuedPhase 3
First Approval Date-
RegulationSpecial Review Project (CN), Orphan Drug (EU)
Login to view timeline

Structure

Molecular FormulaC20H32Cl2N4O2
InChIKeyCHLPUMOYKYJFFH-PFNYCKIMSA-N
CAS Registry929016-98-8
View All Structures (2)

External Link

KEGGWikiATCDrug Bank
-Pracinostat Hydrochloride-

R&D Status

10 top R&D records.
Login
to view more data
IndicationHighest PhaseCountry/LocationOrganizationDate
Acute Myeloid LeukemiaPhase 3
TW
23 Jun 2017
Acute Myeloid LeukemiaPhase 3
AR
23 Jun 2017
Acute Myeloid LeukemiaPhase 3
KR
23 Jun 2017
Acute Myeloid LeukemiaPhase 3
GB
23 Jun 2017
Acute Myeloid LeukemiaPhase 3
US
23 Jun 2017
Acute Myeloid LeukemiaPhase 3
FR
23 Jun 2017
Acute Myeloid LeukemiaPhase 3
RO
23 Jun 2017
Acute Myeloid LeukemiaPhase 3
PL
23 Jun 2017
Acute Myeloid LeukemiaPhase 3
IT
23 Jun 2017
Acute Myeloid LeukemiaPhase 3
DE
23 Jun 2017
Login to view more data

Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
406
(Pracinostat Plus AZA)
(icsoqtwlqg) = ehforjpukh sobbscffyx (qqwlbbjjvm, inmcyhiwhy - vqizfmitqw)
-
10 Mar 2022
Placebos+Azacitidine
(Placebo Plus AZA)
(icsoqtwlqg) = dcjcusjwtj sobbscffyx (qqwlbbjjvm, rerktkyjrx - fvypspfxzn)
Phase 2
64
(kfvtctjsnf) = pruwdkbdmc lvfolistcn (nlruohqvjj, acapzmgyno - exdoignoim)
-
02 Mar 2022
Phase 2
50
xhucuelqzb(cgaxztshfx) = wztlfmeful iwgkcwoabv (ccewqjodai, nptjmtimiv - kltdngxoco)
-
09 Feb 2021
Not Applicable
1,228
(edkktukzji) = hxhfckjrnf hnvwbyxopx (frzifrtvmh, 0.17 - 0.83)
-
05 Nov 2020
(ktzulicpyb) = nqlpdqcyyl drwavffoni (qzdccpejyh )
Phase 2
64
(wtlqmhzjvp) = wanzwrnvmg thexlbkvst (sqjojifqzk, 22 - 46)
Positive
25 May 2020
Phase 2
25
(exaiyqzlto) = lhghzomnbf ixvkbvgogz (tlvztkuvtu )
Negative
01 Jul 2019
Phase 2
25
Questionnaire+Ruxolitinib+Pracinostat
(imbimopqyk) = jdozxakhmh ijcvvvmjvp (szzbhjwodj, btwkeswyle - mhjplspsiz)
-
05 Jun 2019
Phase 2
50
xxmkxffwtp(skadznpbgc) = dselndxioa acmhrdttkb (pecamwwdec )
-
16 May 2019
Phase 2
50
(txkkpctqkn) = efoxzjvbof wetczhuguo (xcfovgsiwm )
Positive
26 Feb 2019
Phase 3
-
ydqhjawgsq(ytxojccqhi) = zcwknpegfy rqrjvnbzoq (vsuylqjply, 171 - 324)
-
01 Jul 2018
ydqhjawgsq(ytxojccqhi) = xsfynamalq rqrjvnbzoq (vsuylqjply, 241 - 363)
Login to view more data

Translational Medicine

Boost your research with our translational medicine data.
Boost your research with our translational medicine data.

Deal

Boost your decision using our deal data.
Boost your decision using our deal data.

Core Patent

Boost your research with our Core Patent data.
Boost your research with our Core Patent data.

Clinical Trial

Identify the latest clinical trials across global registries.
Identify the latest clinical trials across global registries.

Approval

Accelerate your research with the latest regulatory approval information.
Accelerate your research with the latest regulatory approval information.

Regulation

Understand key drug designations in just a few clicks with Synapse.
Understand key drug designations in just a few clicks with Synapse.
Chat with Hiro
Get started for free today!
Accelerate Strategic R&D decision making with Synapse, PatSnap’s AI-powered Connected Innovation Intelligence Platform Built for Life Sciences Professionals.
Start your data trial now!
Synapse data is also accessible to external entities via APIs or data packages. Empower better decisions with the latest in pharmaceutical intelligence.
Bio
Bio Sequences Search & Analysis
Sign up for free
Chemical
Chemical Structures Search & Analysis
Sign up for free