Last update 19 Sep 2024

Sevasemten

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
type II fast skeletal myosin inhibitor (Edgewise Therapeutics), EDG 5506, EDG-5506
+ [1]
Target
Mechanism
MYH4 inhibitors(myosin heavy chain 4 inhibitors)
Inactive Indication-
Originator Organization
Active Organization
Inactive Organization-
Drug Highest PhasePhase 3
First Approval Date-
RegulationFast Track (US), Orphan Drug (US), Rare Pediatric Disease (US), Orphan Drug (EU)

Structure

Molecular FormulaC16H11F4N5O2
InChIKeyXFPJKQRXBAFXNK-UHFFFAOYSA-N
CAS Registry2417395-15-2

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Becker Muscular DystrophyPhase 3--
Muscular Dystrophy, DuchennePhase 2
US
24 Oct 2022
Muscular DystrophiesPhase 1
US
12 Aug 2022
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1
12
cpowxqajvg(tbrfyqqekm) = ndotfrhlnz gcgxqkqhjh (zdbpsatuzw )
Positive
19 Mar 2023
Phase 1
12
pzqqvmhtej(xnhgwiazwy) = 25% Dizziness; 25% Somnolence; 25% Headache; 17% Fall; 8% Gastroenteritis virus pywqdjxofv (ykmhdhdott )
Positive
12 Sep 2022
Phase 1
12
syqbbfheob(xwemdhopgp) = cxjhwtaygg fnixpigzxm (zfgnmrzuht )
Positive
20 Jun 2022
Phase 1
7
helfinzjvb(hwcijnjnlx) = ukeywlwdci gpjsnfolns (hytoksoqwq )
Positive
05 Jan 2022
Placebo
-
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Regulation

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