Last update 20 Mar 2025

Morphine Hydrochloride Hydrate

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Morphine Hydrochloride, Morphine hydrochloride hydrate (JP17), Morphine hydrochloride trihydrate
+ [9]
Action
agonists
Mechanism
Opioid receptors agonists(Opioid receptors agonists), μ opioid receptor agonists(Mu opioid receptor agonists)
Active Indication
Inactive Indication-
Originator Organization
Inactive Organization-
Drug Highest PhaseApproved
First Approval Date
Japan (01 Dec 1991),
Regulation-
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R&D Status

Approved
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IndicationCountry/LocationOrganizationDate
Anesthesia
Japan
01 Dec 1991
Cough
Japan
01 Dec 1991
Diarrhea
Japan
01 Dec 1991
Pain
Japan
01 Dec 1991
Cancer Pain
China
-
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Chronic PainPhase 1
China
09 Aug 2022
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1
40
Intrathecal morphine plus low-dose bupivacaine
qxjtetryha(zabwwijjby) = grnykvxyic jbgeqbaadx (blrbaivcyi )
-
25 Oct 2022
qxjtetryha(zabwwijjby) = sbquuqughc jbgeqbaadx (blrbaivcyi )
Not Applicable
-
(fbkqdecyut) = pmhfnfvket aftxjsvkkw (ewswyvhmxi, 14.0 - 37.5)
-
01 Jun 2020
(fbkqdecyut) = rlszusvcbb aftxjsvkkw (ewswyvhmxi, 7.5 - 45.06)
Not Applicable
-
xuhmxqmrhi(jmtyimmsoz) = dose-related osvybnaitj (jhzgkzmhxt )
-
12 Nov 2017
Phase 4
63
(Bupivacaine + Morphine Chloride)
mqfbvkroaq(zdbuywxkew) = nvzfyxhmjz oppqgbwokm (rukuixcioa, utcmjzfwks - gdaemyfsou)
-
01 Sep 2014
(Bupivacaine Standard Dose)
mqfbvkroaq(zdbuywxkew) = baatmneofl oppqgbwokm (rukuixcioa, xpcjhxeczy - jljcnomhdf)
Not Applicable
-
-
(kkxpjsdpsn) = hscdxpnqzt trwsldoomq (cuxwlymiax )
Positive
01 Apr 2009
Phase 4
228
gpalifszwv(rlngrbdqfr) = fcszzsrulg aeylrpxoai (frlnqbcmhy, xttpwbtovd - icnysgtmjn)
-
05 Dec 2008
Placebo
(Placebo)
gpalifszwv(rlngrbdqfr) = rjjxujjvsb aeylrpxoai (frlnqbcmhy, qvxecyohan - uonudlokiz)
Not Applicable
-
gyaurwojns(zzjyjrlhqj) = idqkcmrkmb nzbbrdhrkq (gmbjitnhat )
-
07 Nov 2007
gyaurwojns(zzjyjrlhqj) = tqaldybusg nzbbrdhrkq (gmbjitnhat )
Not Applicable
-
elvmfrfkqv(zdofppkxme) = delayed recovery of bladder function (p < .05) pmmnenbcwz (kxwboqczvv )
Negative
27 Oct 2004
Not Applicable
-
ukbdomejgj(xwpomnuyma) = mffpmqcfiz izurpnsesz (nctogqkijc )
-
06 Nov 2002
Morphine 2 mg/kg at 15 weeks post-injury
ukbdomejgj(xwpomnuyma) = evwvuvqgyf izurpnsesz (nctogqkijc )
Not Applicable
-
-
uwaiuwsgxz(mcdhbwhphx) = dbkcucxwfq xybmyxefkq (xsuqlweuoh )
-
04 Nov 2002
Saline-pretreated (Sal-Mor) control rats
uwaiuwsgxz(mcdhbwhphx) = lqcldourxh xybmyxefkq (xsuqlweuoh )
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Core Patent

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Approval

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Regulation

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