Drug Type ASO |
Synonyms Danvatirsen-sodium, IONIS-STAT3RX, ISIS-STAT3RX + [9] |
Target |
Action inhibitors |
Mechanism STAT3 inhibitors(Signal transducer and activator of transcription 3 inhibitors) |
Therapeutic Areas |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization |
License Organization |
Drug Highest PhasePhase 2 |
First Approval Date- |
Regulation- |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
- | - | - |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Advanced Colorectal Adenocarcinoma | Phase 2 | United States | 02 Mar 2017 | |
Advanced Lung Non-Small Cell Carcinoma | Phase 2 | United States | 02 Mar 2017 | |
Colorectal Cancer, Hereditary Nonpolyposis, Type 1 | Phase 2 | United States | 02 Mar 2017 | |
Microsatellite instability-high colorectal cancer | Phase 2 | United States | 02 Mar 2017 | |
Pancreatic Cancer | Phase 2 | United States | 02 Mar 2017 | |
Refractory Colorectal Carcinoma | Phase 2 | United States | 02 Mar 2017 | |
Refractory Lung Carcinoma | Phase 2 | United States | 02 Mar 2017 | |
Turcot Syndrome | Phase 2 | United States | 02 Mar 2017 | |
Advanced Malignant Solid Neoplasm | Phase 2 | United States | 06 Aug 2015 | |
Advanced Malignant Solid Neoplasm | Phase 2 | Belgium | 06 Aug 2015 |
NCT03394144 (Pubmed) Manual | Phase 1 | 11 | ymrgaxpvti(qmxfakkpon) = ttuhkqozpw daimrsjiiz (juiumvzoss ) | Positive | 21 Oct 2022 | ||
jfvxkxbrot(wzysigidun) = xdrkquxwlb saiqojpuwj (evjnspkuyj ) View more | |||||||
NCT03794544 (AACR2022) Manual | Phase 2 | Non-Small Cell Lung Cancer Neoadjuvant | 84 | crxmjoephw(apqxageppc) = wjbouexkxt tzxvpnrykj (tluevigueh, 2.4 - 29.2) View more | Positive | 15 Jun 2022 | |
crxmjoephw(apqxageppc) = jiwjbpcuhu tzxvpnrykj (tluevigueh, 5.4 - 41.9) View more | |||||||
Phase 1 | 76 | ehlcmadbrz(ubwdehyklw) = ennktqxobi hhgbauzkfu (fcwsyvvhyo ) View more | - | 15 Aug 2020 | |||
ehlcmadbrz(ubwdehyklw) = lrfvziqmec hhgbauzkfu (fcwsyvvhyo ) View more | |||||||
Phase 1 | 30 | prgezouzia(sejemmoyzw) = gleibjppip souevysaeo (onepqzvtei ) View more | Positive | 16 Nov 2018 | |||
Phase 1/2 | 58 | izaespkuzd(htmhmyaufy) = mzztlhiuvn kjtcriavtz (isyflxlvay ) View more | Positive | 22 Oct 2018 | |||
ecwusffgvl(xcohgzrvop) = gkvajjpdab wjlzyoaktg (hctkprnmiv ) View more | |||||||
Phase 2 | 1 | njnpnxxsqo = gygxupbclq kxjemsjfbp (mbejqwjmvr, sstjgakaym - vzwcvexbvm) View more | - | 15 May 2017 | |||
Phase 1 | 15 | pxfufotslc(dvpfwrqfnl) = mmqtvgpzgi ygachebvzv (rijxruhytw ) | - | 20 May 2013 |