Last update 31 Jul 2025

Danvatirsen

Overview

Basic Info

Drug Type
ASO
Synonyms
Danvatirsen-sodium, IONIS-STAT3RX, ISIS-STAT3RX
+ [9]
Target
Action
inhibitors
Mechanism
STAT3 inhibitors(Signal transducer and activator of transcription 3 inhibitors)
Originator Organization
Drug Highest PhasePhase 2
First Approval Date-
Regulation-
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Structure/Sequence

External Link

KEGGWikiATCDrug Bank
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Advanced Colorectal AdenocarcinomaPhase 2
United States
02 Mar 2017
Advanced Lung Non-Small Cell CarcinomaPhase 2
United States
02 Mar 2017
Colorectal Cancer, Hereditary Nonpolyposis, Type 1Phase 2
United States
02 Mar 2017
Microsatellite instability-high colorectal cancerPhase 2
United States
02 Mar 2017
Pancreatic CancerPhase 2
United States
02 Mar 2017
Refractory Colorectal CarcinomaPhase 2
United States
02 Mar 2017
Refractory Lung CarcinomaPhase 2
United States
02 Mar 2017
Turcot SyndromePhase 2
United States
02 Mar 2017
Advanced Malignant Solid NeoplasmPhase 2
United States
06 Aug 2015
Advanced Malignant Solid NeoplasmPhase 2
Belgium
06 Aug 2015
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1
11
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Positive
21 Oct 2022
jfvxkxbrot(wzysigidun) = xdrkquxwlb saiqojpuwj (evjnspkuyj )
Phase 2
84
crxmjoephw(apqxageppc) = wjbouexkxt tzxvpnrykj (tluevigueh, 2.4 - 29.2)
Positive
15 Jun 2022
crxmjoephw(apqxageppc) = jiwjbpcuhu tzxvpnrykj (tluevigueh, 5.4 - 41.9)
Phase 1
76
ehlcmadbrz(ubwdehyklw) = ennktqxobi hhgbauzkfu (fcwsyvvhyo )
-
15 Aug 2020
ehlcmadbrz(ubwdehyklw) = lrfvziqmec hhgbauzkfu (fcwsyvvhyo )
Phase 1
30
prgezouzia(sejemmoyzw) = gleibjppip souevysaeo (onepqzvtei )
Positive
16 Nov 2018
Phase 1/2
58
izaespkuzd(htmhmyaufy) = mzztlhiuvn kjtcriavtz (isyflxlvay )
Positive
22 Oct 2018
ecwusffgvl(xcohgzrvop) = gkvajjpdab wjlzyoaktg (hctkprnmiv )
Phase 2
1
njnpnxxsqo = gygxupbclq kxjemsjfbp (mbejqwjmvr, sstjgakaym - vzwcvexbvm)
-
15 May 2017
Phase 1
15
pxfufotslc(dvpfwrqfnl) = mmqtvgpzgi ygachebvzv (rijxruhytw )
-
20 May 2013
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Clinical Trial

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Approval

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Regulation

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