Last update 21 Nov 2024

Nifurtimox

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Nifurtimox (USAN/INN)
+ [5]
Target-
Mechanism-
Inactive Indication
Originator Organization
Inactive Organization-
Drug Highest PhaseApproved
First Approval Date
US (06 Aug 2020),
RegulationOrphan Drug (US), Priority Review (US), Accelerated Approval (US)
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Structure

Molecular FormulaC10H13N3O5S
InChIKeyARFHIAQFJWUCFH-UHFFFAOYSA-N
CAS Registry23256-30-6

External Link

KEGGWikiATCDrug Bank
D00833Nifurtimox

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Chagas Disease
US
06 Aug 2020
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
MedulloblastomaPhase 2
US
14 Jan 2008
Neuroblastoma recurrentPhase 2
US
14 Jan 2008
NeuroblastomaPhase 1
CN
20 Oct 2021
Chagas DiseaseDiscovery
BO
27 Jan 2016
Chagas DiseaseDiscovery
AR
27 Jan 2016
Chagas DiseaseDiscovery
CO
27 Jan 2016
Chagas CardiomyopathyDiscovery
AR
01 Nov 2013
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
-
(esjrvuydwo) = No adverse events potentially related to treatment or caused by protocol-required procedures were documented for either treatment regimen cgbpwlefxr (qqxjwrzhqa )
-
28 Mar 2023
Phase 2
112
xremkhthra(bweploepff) = vvxyarnrpj kjywxwkwck (aiukfaowuw, rocgnrywok - grlmzqxjzf)
-
29 Dec 2022
Not Applicable
3,000
aaolaqweai(iccgrihpll) = aqzuwhvnsx jvbqgqlrsn (gnhmmlfgjr, 1.0 - 4.5)
-
01 Oct 2021
(No antitrypanosomal treatment)
aaolaqweai(iccgrihpll) = txzksfqdpr jvbqgqlrsn (gnhmmlfgjr, 1.0 - 4.2)
Phase 3
330
gowjstxxns(hrdtggress): difference = 14.0 (95% CI, 3.7 - 24.2)
Positive
07 Jan 2021
placebo
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Clinical Trial

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Approval

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Regulation

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