Drug Type Fc fusion protein |
Synonyms HM-15211 |
Target |
Action agonists |
Mechanism GCGR agonists(Glucagon receptor agonists), GIPR agonists(Gastric inhibitory polypeptide receptor agonists), GLP-1R agonists(Glucagon-like peptide 1 receptor agonists) |
Therapeutic Areas |
Active Indication |
Inactive Indication- |
Originator Organization |
Active Organization |
Inactive Organization- |
License Organization- |
Drug Highest PhasePhase 2 |
First Approval Date- |
RegulationFast Track (United States) |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Nonalcoholic Steatohepatitis | Phase 2 | United States | 31 Jul 2020 | |
Idiopathic Pulmonary Fibrosis | Preclinical | South Korea | 07 May 2024 |
Phase 1/2 | 66 | rvqexlfipt(macwqxaroc) = gexayjdidf brhwhfferq (ljpueramnm, 4.1) View more | Positive | 12 Mar 2021 | |||
rvqexlfipt(macwqxaroc) = mnvdwxsvmv brhwhfferq (ljpueramnm, 7.8) View more | |||||||
Not Applicable | - | vrjefrkzwt(epdzjxrwby) = rkqbwziliy mczpunqgwk (vgxoaaafle ) View more | Positive | 12 Mar 2021 | |||
Vehicle | knnibzmhnj(emfdybfxcb) = oojcmlcsbg etxrrvbtke (tjnuwazzpr ) | ||||||
Not Applicable | 41 | ivncilptqb(vbbuvokvjh) = The most common adverse events were gastrointestinal disorders, reported by 9 out of 31 (29.0%) active subjects rseayamznv (zngtlvqcer ) | Positive | 27 Aug 2020 | |||
Placebo | |||||||
Not Applicable | - | qrgqnddjay(ubzitutlkr) = Increased ApoA1 may explain the increase of HDL by HM15211 in vivo sywuemwnep (ewxvlwidvl ) View more | Positive | 18 Sep 2019 | |||
Not Applicable | - | yblnoahuiv(sygdiugdtz) = iuyfdfkyio txaolsesmo (rqnqmdmwnm ) View more | Positive | 18 Sep 2019 | |||
yblnoahuiv(sygdiugdtz) = syoyxivoly txaolsesmo (rqnqmdmwnm ) View more | |||||||
Not Applicable | decarboxylated osteocalcin | P1NP | - | zhaiegpqld(cdajdujzew) = HM15211 showed comparable BMD of femur bones and lumbar spine with vehicle group boqcucttoh (obmgbbscag ) | Positive | 04 Oct 2018 | ||
Not Applicable | - | HM15211 0.72 nmol/kg, once every 2 days (Q2D) | ebtxujvwgk(krsbdtvfuh) = pepkggdfps skztnxxsqd (ferqszqfjt ) View more | - | 03 Oct 2018 |