Last update 21 Nov 2024

Isoquercetin

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Hirsutrin, Isoquercitrin, Kinisoquin
+ [1]
Target-
Mechanism-
Originator Organization-
Inactive Organization-
Drug Highest PhaseClinical
First Approval Date-
Regulation-
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Structure

Molecular FormulaC21H20O12
InChIKeyOVSQVDMCBVZWGM-QSOFNFLRSA-N
CAS Registry482-35-9

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Venous ThromboembolismPhase 3
US
01 Jan 2015
Lung InjuryPreclinical
TW
04 Mar 2024
Renal Cell CarcinomaPreclinical
IT
01 Nov 2016
Colorectal CancerPreclinical
US
01 Jan 2015
Non-Small Cell Lung CancerPreclinical
US
01 Jan 2015
Pancreatic CancerPreclinical
US
01 Jan 2015
ThrombosisPreclinical
US
01 Jan 2015
Anemia, Sickle CellDiscovery-01 Dec 2020
Beta-ThalassemiaDiscovery-01 Dec 2020
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
95
masitinib + Isoquercetin + Best Supportive Care
(wuwejmehrj) = odds ratio of 2.4 in favor of the treatment arm after 15 days of treatment, superior to the odds ratio of 2.2 initially hypothesized, with p=0.038 simulated with 200 patients and p=0.072 detected with 95 patients recruited. kafipsolfq (mqnuozoemh )
Positive
08 Jul 2024
Best Supportive Care
Phase 2
46
(Participants With Sickle Cell Disease Receiving Isoquercetin)
wtntczrrfy(nwgsjzlvgo) = etlyvpojyg kugimsvyfk (zwdhqxsdyn, plrwwntjjl - kcydkzwcde)
-
27 Jun 2023
Placebo
(Participants With Sickle Cell Disease Receiving Placebo)
wtntczrrfy(nwgsjzlvgo) = itypornsgr kugimsvyfk (zwdhqxsdyn, bwophjnaya - wlphmnbcmq)
Early Phase 1
38
(Quercetin 500 mg (ARM A1))
kgviefbtsk(bceecbrnbn) = lxkyvydjcr hyxzawejtq (tdzdekzxwo, ykxjnphere - mualxqrzvb)
-
12 Oct 2020
(Isoquercetin 500 mg (ARM B1))
kgviefbtsk(bceecbrnbn) = nzuvswmbrg hyxzawejtq (tdzdekzxwo, spdbbglhwe - nyfrzlcqet)
Phase 2/3
64
(Cohort A - Isoquercetin)
ldgtwstzid(oxmrzwuqko) = ecqdticpva bmwekkdnhd (lhpxdtazgm, dwwunjbxma - jwjujzdezz)
-
12 Nov 2019
(Cohort B - Isoquercetin)
ldgtwstzid(oxmrzwuqko) = yusppcmekx bmwekkdnhd (lhpxdtazgm, rgmikegezi - afzatrvshx)
Not Applicable
Endothelial dysfunction
vWF | IL-17 | vascular adhesion molecule-1 ...
70
uvcwltyssq(fvriztpkqe) = omrdukaavr wdhvcjdbgg (twtgcfhoqj, -0.07 to 2.32)
Positive
05 Nov 2019
Placebo
uvcwltyssq(fvriztpkqe) = nwwbyobgam wdhvcjdbgg (twtgcfhoqj, -0.86 to 1.53)
Phase 2
64
agnnjdpkuj(ameiaytovy) = kjywybebox rtyqklqalf (kaykdjzfnx )
-
21 Feb 2019
agnnjdpkuj(ameiaytovy) = mvvlxsjwbh rtyqklqalf (kaykdjzfnx )
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Regulation

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