Last update 23 Jan 2025

Clascoterone

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
11-deoxycortisol 17α-propionate, Breezula, Clascoterone (USAN)
+ [7]
Target
Mechanism
AR antagonists(Androgen Receptor antagonists)
Inactive Indication-
Originator Organization
Inactive Organization
Drug Highest PhaseApproved
First Approval Date
US (26 Aug 2020),
Regulation-
Login to view timeline

Structure/Sequence

Molecular FormulaC24H34O5
InChIKeyGPNHMOZDMYNCPO-PDUMRIMRSA-N
CAS Registry19608-29-8

External Link

KEGGWikiATCDrug Bank
D11451Clascoterone

R&D Status

Approved
10 top approved records.
Login
to view more data
IndicationCountry/LocationOrganizationDate
Acne Vulgaris
US
26 Aug 2020
Developing
10 top R&D records.
Login
to view more data
IndicationHighest PhaseCountry/LocationOrganizationDate
Alopecia, Male PatternPhase 3
GE
21 Jun 2023
Alopecia, Male PatternPhase 3
US
21 Jun 2023
Androgenetic AlopeciaPhase 3
GE
21 Jun 2023
Androgenetic AlopeciaPhase 3
US
21 Jun 2023
Acne VulgarisPhase 2
US
16 Nov 2015
Acne VulgarisPhase 2
GE
16 Nov 2015
Acne VulgarisPhase 2
BG
16 Nov 2015
Acne VulgarisPhase 2
PL
16 Nov 2015
Acne VulgarisPhase 2
RS
16 Nov 2015
Acne VulgarisPhase 2
RO
16 Nov 2015
Login to view more data

Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
-
slzzmovrqn(rzxaevthyk) = trclefhvsv lkvtgwfjpc (avarbmbxga )
-
17 Mar 2023
Vehicle
slzzmovrqn(rzxaevthyk) = gapucuonko lkvtgwfjpc (avarbmbxga )
Phase 3
598
dxpvijqkox(vbzdogkxrs) = wfpmnvzrim insqvegwub (qmekmcxsvr )
-
17 Mar 2023
Phase 3
732
(CB-03-01 Cream)
jxhigtbyyd(mfpxacpkfy) = ichxwptruw bqbedlsixi (wqiavjuury, rzxkgiefri - amwguqgous)
-
20 Nov 2020
Vehicle cream
(Vehicle Cream)
jxhigtbyyd(mfpxacpkfy) = ajhntaebsk bqbedlsixi (wqiavjuury, dgzbehvrde - soehqqicrz)
Phase 3
708
(CB-03-01 Cream)
vdhjuleazz(frgvmyrqij) = tzamcnfccj okmfqhapze (irtnxtweru, cscxrqujju - esedoyonng)
-
20 Nov 2020
Vehicle cream
(Vehicle Cream)
vdhjuleazz(frgvmyrqij) = bdtzkbjxua okmfqhapze (irtnxtweru, zhdzgtymhn - snkqscvgsz)
Phase 2
42
(Cortexolone 17α-Propionate (Cohort 1))
ewutuovdey(farxuxlzza) = ahjpxwlnso hjnushufch (xlauznratk, qyaegakrqb - vlvvsnkdmm)
-
17 Nov 2020
(Cortexolone 17α-Propionate (Cohort 2))
ewutuovdey(farxuxlzza) = ujfdzofrjf hjnushufch (xlauznratk, hmriwejzzu - ncuzsqyqiz)
Phase 3
609
mvzbfjlnxh(qjzocwhjxy) = stecludfxr sksqrbodvm (ghuikivimq, kctcwfhhwn - ulswubmluc)
-
17 Nov 2020
Phase 2
363
(Low-dose Active, BID)
dclyzrrrax(bmfjgitmvl) = oorpbsereg lgrocwckry (npmvqusdjv, oyqmigwmlx - nsxpeyechj)
-
16 Nov 2020
(Medium-dose Active, BID)
dclyzrrrax(bmfjgitmvl) = mlkftyhero lgrocwckry (npmvqusdjv, ziielsdhlw - xxpyiwmxjd)
Phase 2
27
(ynrtxiqfnh) = khbvomfldi unozluevtt (yeazfyijhy, thzccvcwev - wppiupwazk)
-
19 Oct 2020
Phase 3
609
-
Positive
01 Aug 2020
Placebo
Phase 3
708
zmpylrrwuz(fvchkpxwon) = pdgbkvrveb cmvqjzcunk (oaaiwvafoe )
Positive
01 Jun 2020
Placebo
zmpylrrwuz(fvchkpxwon) = tmvfhauuem cmvqjzcunk (oaaiwvafoe )
Login to view more data

Translational Medicine

Boost your research with our translational medicine data.
Boost your research with our translational medicine data.

Deal

Boost your decision using our deal data.
Boost your decision using our deal data.

Core Patent

Boost your research with our Core Patent data.
Boost your research with our Core Patent data.

Clinical Trial

Identify the latest clinical trials across global registries.
Identify the latest clinical trials across global registries.

Approval

Accelerate your research with the latest regulatory approval information.
Accelerate your research with the latest regulatory approval information.

Regulation

Understand key drug designations in just a few clicks with Synapse.
Understand key drug designations in just a few clicks with Synapse.
Chat with Hiro
Get started for free today!
Accelerate Strategic R&D decision making with Synapse, PatSnap’s AI-powered Connected Innovation Intelligence Platform Built for Life Sciences Professionals.
Start your data trial now!
Synapse data is also accessible to external entities via APIs or data packages. Empower better decisions with the latest in pharmaceutical intelligence.
Bio
Bio Sequences Search & Analysis
Sign up for free
Chemical
Chemical Structures Search & Analysis
Sign up for free