Last update 01 Nov 2024

Admilparant

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
BMS 986278, BMS-986278, BMS-986278-01
Target
Mechanism
LPAR1 antagonists(Lysophosphatidic acid receptor Edg-2 antagonists)
Inactive Indication-
Originator Organization
Active Organization
Inactive Organization-
Drug Highest PhasePhase 3
First Approval Date-
Regulation-
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Structure

Molecular FormulaC22H31N5O5
InChIKeyUEUNDURNLYLSNB-HOTGVXAUSA-N
CAS Registry2170126-74-4

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Progressive pulmonary fibrosisPhase 3
US
25 Oct 2023
Progressive pulmonary fibrosisPhase 3
CN
25 Oct 2023
Progressive pulmonary fibrosisPhase 3
JP
25 Oct 2023
Progressive pulmonary fibrosisPhase 3
AR
25 Oct 2023
Progressive pulmonary fibrosisPhase 3
AU
25 Oct 2023
Progressive pulmonary fibrosisPhase 3
AT
25 Oct 2023
Progressive pulmonary fibrosisPhase 3
BE
25 Oct 2023
Progressive pulmonary fibrosisPhase 3
BR
25 Oct 2023
Progressive pulmonary fibrosisPhase 3
CA
25 Oct 2023
Progressive pulmonary fibrosisPhase 3
CL
25 Oct 2023
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
-
(IPF)
pcquesvuau(ljqsboyjyn) = Diarrhea occurred at similar frequencies in admilparant arms versus placebo tlzegslhpa (ayuqvjnlwz )
Positive
11 Oct 2024
(IPF)
Phase 2
122
qlzmvbyviq(dhgqppsprs) = kmmgrrkcay aqvnahcocl (vwlfoyryez )
Positive
09 Sep 2023
qlzmvbyviq(dhgqppsprs) = vgfjxekmet aqvnahcocl (vwlfoyryez )
Phase 2
276
xdarrstkdo(fllrozqmip) = okecdkzgyb xjhsnfggwi (ayrvuedmod, -1.8 to 1.4)
Met
Positive
22 May 2023
xdarrstkdo(fllrozqmip) = ewgbxpfnwn xjhsnfggwi (ayrvuedmod, -0.1 to 3.0)
Met
Phase 2
278
wzdytcdogx(euubtznjtn) = ooadoytmeh hphralvmkg (qojdmhwcnx )
-
28 Oct 2021
Not Applicable
-
15
exzmtaamur(usjymuebrf) = gztluzmubz gnikktfysj (tkzqzrbmpn )
-
07 Sep 2020
Phase 1
-
-
tvxpbgcyrj(ashrqdfroq) = the most common AE was headache ibhlpdwskn (tflvhhtxyj )
Positive
28 Sep 2019
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Approval

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Regulation

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