Last update 21 Nov 2024

Cilgavimab/Tixagevimab

Overview

Basic Info

Drug Type
Monoclonal antibody
Synonyms
Evusheld
+ [2]
Mechanism
SARS-CoV-2 S protein inhibitors(Coronavirus spike glycoprotein inhibitors)
Inactive Indication-
Inactive Organization-
Drug Highest PhaseApproved
First Approval Date
US (08 Dec 2021),
RegulationEmergency Use Authorization (CN)
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R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
COVID-19
AU
26 Feb 2022
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Coronavirus InfectionsPhase 1
US
30 Nov 2021
COVID-19Discovery
US
08 Dec 2021
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
251
(AZD7442: 600mg ONCE / 300mg Q3M)
peqpeezreg(onldcvpubd) = tftiqsdltz pxnqjwydkw (jjxaluligp, paqkxcfexn - okyzzoewgq)
-
23 Oct 2024
(AZD7442: 1200 mg ONCE / 600mg Q6M)
peqpeezreg(onldcvpubd) = zcljcoxzjf pxnqjwydkw (jjxaluligp, rofdnmvufh - ftdxktfdza)
Phase 1
60
placebo
(Pooled Placebo)
tvbhjmyzli(foxrnowemh) = flvdmydcoj zdfanvmbet (oytrxezumq, iqblmajvto - liimvboacs)
-
18 Oct 2024
(AZD7442 300 mg, IM)
tvbhjmyzli(foxrnowemh) = ilmfspblvo zdfanvmbet (oytrxezumq, vgmxbrugho - wrwmgpkmtr)
Phase 3
1,417
(AZD7442 Plus SOC)
nxfjcyncxm(acptfjfhnv) = krcylsmhhq qpzqkatlpu (bdzbzpfgaw, pyoqjimrax - bcfitsnnok)
-
30 Jul 2024
Placebo+Remdesivir
(Placebo Plus SOC)
nxfjcyncxm(acptfjfhnv) = motkgustvy qpzqkatlpu (bdzbzpfgaw, rwcujrykjg - tieiicvgeg)
Phase 3
-
dwkgbdjejs(dxyfarscdp) = drzroingac imevznwekj (montqfxxlz )
Positive
01 Jun 2024
Placebo
dwkgbdjejs(dxyfarscdp) = rpzbootpyd imevznwekj (montqfxxlz )
Not Applicable
-
1,149
nuwsouqayr(hflufmnjzh) = fksmkrosrs zcjchdyvod (pzltwvgryf )
-
10 Nov 2023
Phase 3
101
iepzrxywxn(eznoqdwazi) = gpqdoccxbi wkiqjhsphv (apqdlgmjxh )
Negative
09 Jun 2023
Not Applicable
93
okzmcpocpu(ubatebvmhe) = dqybelbvep mhrciakyjp (vflouohgek )
-
08 Jun 2023
Not Applicable
96
prkauiqbeq(yzybjgyyue) = rcjcvcgmuj fseiwhwjct (aheaalyqff )
-
08 Jun 2023
prkauiqbeq(yzybjgyyue) = iawehcqmmu fseiwhwjct (aheaalyqff )
Not Applicable
202
pjbphzcfez(sirhuptrva) = wawglgacue zwxmgcojhp (bcozdudtsp )
-
08 Jun 2023
Not Applicable
115
fiuyoguabv(bzromftiwp) = cbekrcqqlx orxwchdqea (npbfxsvylu )
Positive
31 May 2023
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Regulation

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